Hydrogenovibrio thermophilus: EPV75_04530
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Entry
EPV75_04530 CDS
T05808
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
htr
Hydrogenovibrio thermophilus
Pathway
htr00290
Valine, leucine and isoleucine biosynthesis
htr00660
C5-Branched dibasic acid metabolism
htr01100
Metabolic pathways
htr01110
Biosynthesis of secondary metabolites
htr01210
2-Oxocarboxylic acid metabolism
htr01230
Biosynthesis of amino acids
Module
htr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
htr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
EPV75_04530 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EPV75_04530 (leuC)
Enzymes [BR:
htr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
EPV75_04530 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
EPV75_04530 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QAB14987
UniProt:
A0A410H242
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Position
980753..982177
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AA seq
474 aa
AA seq
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MSAKTLYDKLWDSHVVRQEEDGTALIYIDRQLLHEVTSPQAFEGLRLANRKPWRVNANLA
TPDHNVPTTPYKTVDDIADPISRIQVQTLDANTKHFGITEFGIGDIRQGIVHVVGPEEGM
TLPGITLVCGDSHTATHGALGALAHGVGTSEVEHVLATQCLIQKKMKNMLIKVDGQLQPG
VTPKDVVLAIIGKIGTAGGNGHAIEFGGQVFRDMSIEGRMTVCNMAIEAGARVGLVAVDD
KTIEYVKGRPMAPKDDQWEMAVQAWQDLKSDDDAVFDKVVEIDGASIEPQVSWGTSPEMV
LDVNGKVPNPANESDEVKASGIRRALEYMGLEADMAITDIPVDYVFIGSCTNSRIEDFRE
AAAVLKGRKVAASVEQAIVVPGSGLVKQQAEAEGLDKIFIEAGFEWRNPGCSMCLAMNAD
KLPSGKHCASTSNRNFEGRQGAGGRTHLVSPQMAAAAAVAGHFVDVRDMMKEAV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgtctgccaagaccttatacgataaattgtgggacagccatgtcgtccgtcaggaagaa
gacgggacggcgttgatttacattgaccgtcagttgttgcatgaagtgacttcgcctcaa
gcgtttgagggcctgcgtctcgccaatcgtaaaccttggcgcgtcaacgccaacttggcg
acgccggatcataacgtgccgaccacgccgtataaaacggtggacgacatcgccgatccg
atttcgcggattcaggtacagacattggatgccaataccaaacatttcgggattaccgaa
ttcggtatcggcgacattcgccagggcatcgtgcacgtagtcgggccggaagaagggatg
actttgccgggcatcacgttggtgtgcggtgactctcatacggcgacgcacggagcttta
ggtgctttggcacatggtgtggggacatcggaagtggagcacgtgctggccacgcaatgc
ttgattcaaaagaaaatgaaaaacatgttgatcaaggtggacggtcaattgcagccgggg
gtcacaccgaaagatgtggtcttggcgattatcggcaaaatcggtaccgccggcggcaac
ggtcatgctatcgaattcggcggacaggtgttccgggatatgtcgatcgaagggcgtatg
accgtgtgtaacatggcgattgaagccggtgcgcgtgttggtttggtggcggtggatgat
aagaccatcgaatatgtaaaaggccgcccgatggcaccgaaagacgaccagtgggaaatg
gccgttcaggcctggcaagatttgaaatccgacgatgatgccgtgttcgataaggtggtg
gaaatcgacggtgccagcatcgaaccacaagtgtcttggggaacgtcgccggaaatggtc
ttggacgtcaatggcaaagtgccgaatccagccaacgagtccgacgaagtcaaagccagc
ggcattcgccgcgcgttggaatacatgggtctggaagccgatatggcgattaccgatatt
ccggtggattatgtcttcatcggttcctgtaccaactcgcgcatcgaggattttcgtgaa
gcggcggcggtgttgaaaggccgtaaagtagccgcttcggttgagcaagcgatcgtggtg
ccggggtccggtctggtcaaacaacaagccgaagccgaagggttggataagattttcatc
gaggccggtttcgagtggcgtaacccgggctgctcaatgtgtttggcgatgaacgccgat
aaactgccgagcggtaagcactgtgcctccacgtcgaaccgtaacttcgaagggcgtcag
ggcgctggcgggcgcacgcatttggtcagtccgcaaatggccgctgccgcagcggtggcc
gggcattttgtggacgtacgtgacatgatgaaagaagcggtttaa
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