Haloferax volcanii DS2: HVO_1088
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Entry
HVO_1088 CDS
T01200
Symbol
folCP
Name
(GenBank) folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase
KO
K24102
dihydrofolate synthase / dihydropteroate synthase [EC:
6.3.2.12
2.5.1.15
]
Organism
hvo
Haloferax volcanii DS2
Pathway
hvo00790
Folate biosynthesis
hvo01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hvo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HVO_1088 (folCP)
Enzymes [BR:
hvo01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
HVO_1088 (folCP)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HVO_1088 (folCP)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
Mur_ligase_C
Mur_ligase_M
DUF6211
Motif
Other DBs
NCBI-ProteinID:
ADE02963
UniProt:
D4GW05
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All DBs
Position
993598..996114
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AA seq
838 aa
AA seq
DB search
MEYHEAVNFLFDLRRFQVKPGTESIRRLLSHLGDPHEGVSFVQVAGSNGKGSTARMVDAM
LRESGAHVGLYTSPHFDDVRERVRVDGRKIPKSALSAFVAEAKPYLVERAADGEPLTFFE
TVTALALWYFDRAGVDVAVLEVGMGGELDATSAVDPVASAVTNVSLEHTAVLGDTVAEIA
KTKAAVAPADAPLVTGTTGEALSVIREEAGDVLTVGDADADSDADVRVSYGGRVNHQEAA
VTVETDAETLDVRIPLLGAYQARNAGIAVSLARQVRPDIDAEAIHRGLRNAHWPGRFEVM
GTEPTVVLDGAHNPDACAQVATVLDEFDYDDLHLVYGAMHDKDHGEMVGALPEVASVVTC
KADISRGEDPEILSSVFERLNGPAVETGGAVAAALDRARARADPDDCVLVVGSLYVVAEA
RTTWTRAVVPKTHRTLDDARRTLDRANVADAAERSERARRAVNRTVHTRVQRRQARVLRE
ELLSVGGDCAVSGHEFGGELVDVVLTGTLDQFERLTAALEDPPYALAGVAAEIRETLDIE
AADAGEDDERGAGDASDAGHDDYPWNDGTAVMGILNVTPNSFHDGGEFYDIDDAVEQARA
MVDAGVDIIDVGGESTRPGADEVPVDEEIRRVAPVIEAIADLDVLVSVDTRKAAVGAAAL
DAGADILNDVTGLEDPEMRFLAAERGAPVIVMHSIDAPVDPSREVDYDDVVEDVIDELTE
LVLLAEKAGIPRRNLIVDPGLGFGKSKAENFELLGRTDEFAALGCPILVGHSHKSMFSLV
GEEPGDNLAATVAGTAIAADRGADIVRVHDVPENVAAVNVALASRDPNRFEADAERED
NT seq
2517 nt
NT seq
+upstream
nt +downstream
nt
atggagtaccacgaggcggtgaacttccttttcgacctccggcggtttcaggtcaagccg
gggaccgagtcgattcggcggttgctctctcacctcggcgacccccacgaaggcgtgtcg
ttcgtgcaggtcgcggggtcgaacggaaagggaagcaccgcccggatggtcgacgcgatg
ctgcgcgagtcgggcgcgcacgtcggcctctacacctcgccgcacttcgacgacgtgcgg
gagcgcgtccgcgtcgacggccggaagattccgaagtccgcgctgtcggcgttcgtggcc
gaagccaagccgtacctcgtcgagcgggccgccgacggcgagccgctgaccttcttcgag
accgtgaccgcgctcgcgctgtggtacttcgaccgcgcgggcgtcgacgtggcggtgctc
gaagtcgggatgggcggcgaactcgacgcgacgagcgccgtcgaccccgtcgccagcgcc
gtcaccaacgtctcgctcgaacacaccgcggtcctcggcgacacggtcgcggaaatcgcg
aagacgaaagccgccgtcgcgcccgccgacgcgccgctcgtgaccgggacgaccggcgag
gcgctgtcggtcatccgcgaggaggccggcgacgtgttgaccgtcggggacgccgacgcc
gactcggacgcggacgttcgcgtctcctacggcggccgcgtcaaccaccaggaggccgcc
gtcaccgtcgagaccgacgccgagacgctcgacgttcgcatcccgcttttgggcgcgtat
caggcacggaacgccggcatcgccgtctcgctcgcccggcaggttcgcccggatatcgac
gcggaggcgattcaccgcggcctccgaaacgcccactggccgggtcggttcgaggtcatg
ggtacggagccgacggtcgtcctcgacggcgcgcacaaccccgacgcctgcgcgcaggtc
gccaccgtcctcgatgagttcgactacgacgacctccatctcgtctacggcgcgatgcac
gacaaggaccacggcgagatggtcggggcgctcccggaggtggcgtccgtcgtcacctgc
aaggcggacatctcgcggggcgaggaccccgagatactgtcgtccgtcttcgagcgactc
aacggccccgcagtcgagaccggcggcgcggtcgccgcggcgctcgaccgggcgcgcgcc
cgcgccgaccccgacgactgcgtgctcgtcgtcggctcgctgtacgtcgtcgccgaggcg
cggaccacgtggacgcgggcggtcgtcccgaagactcaccgcacactcgacgacgcccga
cggaccctcgaccgcgcgaacgtcgctgacgccgccgaacggagcgaacgcgcgaggcgg
gcggtcaacagaacggtccacacgcgcgtccagcgccggcaggcgcgggtgctccgcgag
gaactgctgtccgtcggcggcgactgcgccgtctcgggccacgagttcggcggcgaactc
gtcgacgtggtcctgaccgggacgctcgaccagttcgagcgcctgacggcggccctcgaa
gacccaccgtacgcgctcgcgggggtcgcagccgagattcgcgagacgctcgacatcgag
gcggctgacgccggcgaagacgacgagcgcggcgcgggcgacgcgagcgacgccggccat
gacgactacccgtggaacgacggcacggccgtcatgggcatcctgaacgtgacgccgaac
agtttccacgacggcggggagttctacgatatcgacgacgccgtcgagcaggcgcgggcg
atggtcgacgccggcgtcgacatcatcgacgtgggcggcgagagcacccgccccggcgcg
gacgaggtcccggtcgacgaggagattcgccgcgtcgcgcccgtcatcgaggccatcgcc
gacctcgacgtgctcgtgtccgtggacacccgcaaggccgcggtcggcgcggccgccctc
gacgccggcgcggacatcctcaacgacgtgaccggcctcgaagaccccgagatgcgcttc
ctcgcggccgagcgaggcgcgccggtcatcgtgatgcacagcatcgacgccccggtcgac
ccgtctcgcgaagtcgactacgacgacgtggtcgaggacgtcatcgacgaactgaccgag
ctggtgttgctcgccgagaaggcgggcatcccgcggcggaacctcatcgtcgaccccggt
ctcggcttcgggaagtcgaaggccgagaacttcgaacttctcgggcgcaccgacgagttc
gccgcgctcggctgtccgattctcgtcggccactcccacaagtcgatgttctcgctcgtc
ggcgaggagcccggcgacaacctcgcggcgaccgtcgcgggcacggcaatcgccgccgac
cgcggggccgacatcgtccgcgtccacgacgtgccggagaacgtcgcggccgtgaacgtc
gcgctcgcctcccgggacccgaaccggttcgaagccgacgccgagcgcgaagactga
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