Hydrogenophaga sp. PBC: Q5W_03850
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Entry
Q5W_03850 CDS
T04491
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hyb
Hydrogenophaga sp. PBC
Pathway
hyb00790
Folate biosynthesis
hyb01100
Metabolic pathways
hyb01240
Biosynthesis of cofactors
Module
hyb_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
hyb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Q5W_03850
Enzymes [BR:
hyb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Q5W_03850
6.3.2.17 tetrahydrofolate synthase
Q5W_03850
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AOS78174
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Position
783396..784742
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AA seq
448 aa
AA seq
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MLEIPVPDHPVSLADWLAHAERLHPQAIDMGLERVQTVARRMGLQLNCPVITVAGTNGKG
STCAMLESIYTQSGYRTGVYTSPHLVHFEERCRIGGEVVSAEELVPAMAEVDVARRGQGG
EPEVSLTYFEFTTLAILRVIARAAVDVAILEVGLGGRLDAVNILDADCAVITSIDLDHMA
LLGPDRESIGREKAGIMRTGRPVVVSDPAVPQSVIDHAREIDADLWRVGADFHVAGDQQQ
WGWATHPSRGGRRYSGLAYPALRGANQLLNAAGVLAAIETLRGRLPVTAQAVRTGFVLVE
LPGRFQILPGRPTLVLDVAHNPHSVAALAVNLDAMGFYPRTHAVFGAMADKDLNTMLARI
APLIDHWYLTDLPLPRASRAADLRPLIEALPGAIPRETSTHASPREALAAALSAVDPADR
IVVFGSFYTVGGVLQDGLPKLAAPHLAA
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgcttgagatccccgttcccgaccatcccgtgtcgctggccgactggctcgcccacgcc
gagcgcctgcacccgcaggccatcgacatgggcctggagcgcgtgcagaccgtggcgcgg
cgcatgggcctgcaactgaattgcccggtgatcaccgtggccggcaccaacggcaagggc
agcacctgcgccatgctggagtccatctacacgcaatcggggtaccgcaccggcgtgtac
acctcgccgcacctggtgcatttcgaggaacgctgccgcatcggcggcgaggtggtgtcg
gccgaggagttggtgcccgccatggccgaggtggacgtggcgcggcgcggccagggcggc
gagcccgaggtgagcctgacctacttcgagttcaccacgctggccatcctgcgcgtcatc
gcgcgcgcggcggtggacgtggccatcctcgaggtcggcctgggcggccggctcgacgcg
gtcaacatcctcgacgccgactgcgccgtcatcaccagcatcgacctcgaccacatggcc
ctgctgggccccgaccgcgaaagcatcggccgcgagaaggccggcatcatgcgcaccggt
cgccccgtggtagtgagcgacccggcggtgccgcagagcgtgatcgaccacgcccgcgag
atcgacgccgacctctggcgcgtgggcgccgatttccacgtcgcgggcgaccagcagcag
tgggggtgggccacgcacccctcgcgcggcgggcgacgctacagcggcctggcctacccg
gcgctgcgcggcgccaaccagttgctcaacgcggccggcgtgctcgccgccatcgaaacc
ctgcgggggcgcctgcccgtcacggcccaggcggtgcgaaccggcttcgtgctggtggag
ctgcccgggcgtttccagatcctgcccgggcggcctacgctggtgctcgacgtggcgcac
aacccgcactcggtggccgcgctcgcggtcaatctcgacgccatgggcttctacccgcgc
acgcacgccgtgttcggcgccatggccgacaaggacctgaacaccatgctggcgcgcatc
gcgccactgatcgaccactggtacctcaccgatctgcctttgccgcgcgcgagccgggcc
gcggatctgcggcccctcatcgaggccctgcccggcgccattccgcgcgaaaccagcacc
catgcgagcccgcgtgaggcattggccgcggccctgagcgcggtggaccccgctgataga
atcgtggtctttggctcgttctacaccgtcggtggtgtgctgcaggacggattgccgaaa
ctcgcggccccgcacctcgccgcctga
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