Hydrogenophaga sp. PBC: Q5W_16610
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Entry
Q5W_16610 CDS
T04491
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hyb
Hydrogenophaga sp. PBC
Pathway
hyb00300
Lysine biosynthesis
hyb00550
Peptidoglycan biosynthesis
hyb01100
Metabolic pathways
hyb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hyb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Q5W_16610
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Q5W_16610
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Q5W_16610
Enzymes [BR:
hyb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Q5W_16610
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
OHCU_decarbox
DUF5713
Motif
Other DBs
NCBI-ProteinID:
AOS80476
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Position
complement(3502715..3504142)
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AA seq
475 aa
AA seq
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MKTLAELLPTLPGARAVGRIAAPIERVHSDTRSLRAGDLFVALKGERFDAHEFLPQAAAT
GAVAALAQRGLAEAGLPGVEVPDTRAALLQLAQAWRAQFTLPLIAVTGSNGKTTVTQMVA
SILRAHASEAAHATQGNFNNDIGVPLTLLRLNAAHRCSVVELGMNHPGEIAQLAAIAAPT
VALVNNAQREHQEFMSSVEAVARENGTVITALGAEGVAVFPSDDVHTRIWQALAGARRTI
TFSDPDPQAAVRALAAEWQDNAWALHFASPLGEGQVQLRIAGRHNVRNALAAVACAVAAD
VPLDAIVAGLNAFEPVGGRSRAITVRVDARVVTLIDDTYNANPDSVRAAIDVLAALPGPH
LLVLGDMGEVGDQGLAFHLEVLRHAYARGIDEVRVSGTAMCEAAEAMRAANEPAPRCVPE
VEALATDVAAELATGVVASVLVKGSRFMRMERVVRAVRALDPTQAVNDKDSSHAA
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgaagaccctggccgaactcctgcccacgctgcccggcgcgcgcgccgtcggccgcatc
gccgcgcccatcgagcgcgtgcattccgacacccgcagcctgcgcgcgggcgatctgttc
gtcgcactcaagggcgagcgtttcgacgcgcacgagttcctgccgcaggcggccgccacc
ggtgccgtggccgcgctcgcgcagcgcggcctggccgaggccggcctgcccggcgtggag
gtgcccgacacgcgtgccgcgctgctgcagctcgcgcaggcctggcgcgcgcagttcacg
ctgcccttgatcgccgtgaccggcagcaacggcaagaccacggtcacccagatggtcgcg
agtatcctgcgcgcccacgcgagcgaggccgctcacgccacgcagggcaacttcaacaac
gacatcggcgtgccgctcacgttgctgcggctgaacgccgcgcaccgttgttcggtggtg
gagctgggcatgaaccacccgggcgagatcgcccagctcgccgccatcgccgcacccacc
gtggccctggtcaacaacgcccagcgcgagcaccaggagttcatgagctcggtggaggcc
gtggcgcgagagaacggcaccgtcatcaccgcgctgggcgccgagggcgtggccgtgttc
cccagcgacgacgtgcacacccgcatctggcaggccctggccggcgcgcgccgcacgatc
accttcagcgaccccgatccgcaagccgccgtgcgtgccctcgccgccgagtggcaggac
aacgcctgggcgctgcacttcgcctcgcccctgggcgagggtcaggtgcaactgcgcatc
gccggccgccacaacgtgcgcaacgcgctggcggccgtggcctgcgcggtggccgccgac
gtgccgctcgacgccatcgtggcgggcctgaacgccttcgagcccgtgggtgggcgctcg
cgcgcgatcacggtgcgggtcgacgcccgcgtggtcacgctgatcgacgacacctacaac
gccaaccccgactccgtgcgcgccgccatcgacgtgctggccgcgttgcccggcccgcac
ctgctggtgctgggtgacatgggcgaggtgggcgaccagggcctggccttccacctggag
gtgctgcgccacgcctacgcgcgcggcatcgacgaggtgcgcgtgagtggcacggccatg
tgcgaagccgccgaggccatgcgcgcggccaacgagcccgcgccgcgctgcgtgcccgag
gtggaggcgctggccaccgacgtcgccgccgagctggccaccggcgtggtcgccagcgtg
ctcgtgaagggctcgcgcttcatgcgcatggagcgcgtggtgcgggcggttcgcgcgctc
gacccgactcaggccgtcaacgacaaggattcgtctcatgctgcctag
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