Hymenobacter sp. DG25B: PK28_16530
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Entry
PK28_16530 CDS
T03500
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hyd
Hymenobacter sp. DG25B
Pathway
hyd00300
Lysine biosynthesis
hyd00550
Peptidoglycan biosynthesis
hyd01100
Metabolic pathways
hyd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hyd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PK28_16530
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PK28_16530
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PK28_16530
Enzymes [BR:
hyd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PK28_16530
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AIZ64871
UniProt:
A0A0A7LNC8
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Position
3847819..3849114
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AA seq
431 aa
AA seq
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MSEPTALYSRFLECQSVSTDTRQEQDNTLFFALNGPSFRGRDFAPQALAKGARYAVVDDE
ALAATDARYTYAPDPLLALQELARHHRRQLTIPVLAVTGSNGKTTTKELLHAVLSRRYRV
QYTKGNLNNHIGVPLTLLSIKADLHEFALVEMGANHQGEIDLLCRLAEPTHGLITNIGKA
HLEGFGGLEGVAKGKSEMWRFLAAHAGTAFVNTADAQVAQLAEVVPTRITYPNPADTYPA
ELLSATPNVVLRLFDGSVVEAQINGGYNFLNLAAAAAVGAHFGVPTPDIAQALAGYAPTN
NRSQLLRTQRNELVLDAYNANPSSMAAALASFATRPGDASRKMVVLGDMFELGPESAAEH
RAMGELLSGYSFGTVVLCGPEMAAAQARPEFLHFNTKTEATAWLREHPVQNHQILIKGSR
GMGLETLVELL
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgagtgagcccactgctctttattcccgctttctcgaatgtcaatcggtcagcaccgac
acgcggcaggagcaagataacacgctgttttttgccctgaacggtcccagcttccggggc
cgtgattttgccccgcaggccctggccaaaggcgcccgctacgccgtggtagacgacgaa
gccctggccgccactgacgcgcgctatacttacgcccccgacccgcttttggctttgcag
gagctggcccgccaccaccggcggcagcttaccattccggtgctggccgtaacgggctcc
aacggcaaaactaccaccaaggagctgctgcacgccgtgctgagccgccgctaccgcgta
cagtataccaaaggcaaccttaacaaccacattggggttccgctcacgctgctcagtatt
aaggctgatctgcacgagtttgccctggtagaaatgggcgccaaccaccaaggggaaatt
gacttgctctgccggctggcggaacccacgcacgggctcattaccaacattggcaaagcc
catctggagggcttcggtgggctggaaggcgtggccaaaggcaagagtgaaatgtggcgc
ttcctggccgcccacgccggcaccgccttcgtgaatacggccgatgcgcaggtagcgcag
ctggccgaggtagtacccacgcgcatcacttaccccaaccctgccgatacctacccggcc
gagctgctgagcgctacccccaacgtggtgctgcgcctgtttgatggctcggtagtggaa
gcgcagattaatggtggctacaattttctgaacctggccgccgccgccgccgtgggcgcc
cattttggagtacccaccccggatattgcgcaggctctggccggctacgcgcccaccaac
aaccgctcccagctgctgcgcactcagcgcaacgagctggtgctggatgcctacaatgcc
aaccccagcagcatggccgccgccctggccagctttgccacccgccccggcgatgccagc
cgcaaaatggtagtgctgggcgacatgtttgagctgggcccggaaagcgccgccgagcac
cgcgctatgggtgagctgctgagcggttacagttttggaaccgtagtgctctgcggcccg
gaaatggctgctgcccaggcccggccagagtttctgcacttcaacacgaagacggaagcc
actgcctggctgcgcgaacaccctgtgcagaaccaccagattctgattaaaggctcccgc
ggcatgggtctggaaaccctggtggagctgctgtaa
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