Iamia sp. SCSIO 61187: HC251_14945
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Entry
HC251_14945 CDS
T07394
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
iam
Iamia sp. SCSIO 61187
Pathway
iam00300
Lysine biosynthesis
iam00550
Peptidoglycan biosynthesis
iam01100
Metabolic pathways
iam01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
iam00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HC251_14945
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HC251_14945
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HC251_14945
Enzymes [BR:
iam01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HC251_14945
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QYG93593
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Position
complement(3144962..3146296)
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AA seq
444 aa
AA seq
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MRLTLTDLATATGGSVAGDAATVVDGLGIDSRALPPGAGFVALVAERDGHDFVAGAVAAG
AVAVVASRPVGDVGVPVLLVPDTAAALLAIGRLARSRLPDRVVGITGSVGKTSTKDMLAS
LLAARWTTAASARSFNNEIGVPLTLVAAPADTGAAVIEMGARGPGHIALLCTIARPTAAI
VTAVADAHLEMFGSIDEVARAKGELVEALPSDGVAVLNADDPRVAAMAGRTSASVLTYGV
GKGSTADVVATDVELDDLLRPRLVLRSPWGVIPVRLRVHGAHQAANAVAAAACALALGVD
LDDVVEALGAAAISGMRMQVDRAPSGLVVVNDAYNANPTSTRAALDALAALPVTGRKVAV
LGLMAELGPDADELHRGVAAAAADRGIEVVSVAAPAYGAATAVDDPADAVGCLRGLAAGD
AVLIKGSRVAGLEAVAESLLAAEA
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
gtgcggctcaccctcaccgacctggccaccgccaccggcggctccgtggcgggcgacgcc
gcgaccgtggtggacggtctcggcatcgactcccgggcccttccgcccggcgccggcttc
gtcgccctggtcgccgagcgcgacgggcacgacttcgtcgccggggcggtcgccgcggga
gcggtggcggtggtcgcctcccgaccggtgggcgatgtgggcgtccccgtcctgctggtg
cccgacaccgccgctgccctcctcgccatcggccgcctggcccgcagccgcctgcccgat
cgggtcgtgggcatcaccgggtcggtcggcaagacctcgaccaaggacatgctcgccagc
ctgctggccgcccggtggacgacggcggccagcgcccgctcgttcaacaacgagatcggc
gtgcccctgacgctcgtggccgcgccggccgacaccggtgccgccgtcatcgagatgggc
gcccggggcccgggccacatcgctctgctgtgcacgatcgcccgcccgacagcggcgatc
gtcaccgccgtcgccgacgcccacctcgagatgttcgggtcgatcgacgaggtggcccgg
gccaagggcgagctggtcgaggccctgccgtccgacggcgtcgccgtcttgaacgccgac
gaccctcgcgtcgcggcgatggccgggcggacctcggcgtcggtcctgacctacggggtg
gggaaggggtcgacggccgacgtggtcgccaccgacgtggagctcgacgacctgctccgt
ccccggctggtgctgcgctcgccgtggggcgtgatccccgtccggctccgggtccacggc
gcccaccaggcggccaacgccgtcgccgccgcagcctgcgccctggccctcggcgtcgac
ctcgacgacgtggtcgaggccctcggggccgccgccatctccgggatgcgcatgcaggtc
gatcgggcgccgtcgggcctggtcgtggtgaacgacgcctacaacgccaacccgacctcg
acccgggccgccctcgacgccctggccgccctgccggtcaccgggcgcaaggtggcggtg
ctggggctgatggccgagctggggcccgacgccgacgagctccaccggggcgtcgccgcc
gccgccgccgaccggggcatcgaggtggtgagcgtggccgcgcccgcctacggggcggcg
accgcggtcgacgacccggccgacgcggtggggtgcctccgggggctggccgccggagat
gccgtgctgatcaaggggagccgggtcgccggcctggaggcggtggccgagtccctcctc
gccgccgaggcctga
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