Intrasporangium calvum: Intca_0660
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Entry
Intca_0660 CDS
T01385
Name
(GenBank) Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ica
Intrasporangium calvum
Pathway
ica00860
Porphyrin metabolism
ica01100
Metabolic pathways
ica01110
Biosynthesis of secondary metabolites
ica01120
Microbial metabolism in diverse environments
ica01240
Biosynthesis of cofactors
Module
ica_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ica_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ica00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Intca_0660
Enzymes [BR:
ica01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Intca_0660
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Intca_0660
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Succ_DH_flav_C
Motif
Other DBs
NCBI-ProteinID:
ADU47205
UniProt:
E6SAF5
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Position
718556..720202
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AA seq
548 aa
AA seq
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MTRTRQPSEQTATIPTVPTMPARVAFVGSGPGDPGLLTVRARDLLAAADVVVLDGLMREE
AVLGHAREDVQIIDAAHGENGQELTHAVRAKLVVKAAKSVSNGGLVVRLMDGDPATFNGL
VEEARACRKAGITFDVVPGVSAATAVATYAGVPLTSKGTSSVHVLNADQSGHDLTRYCTD
DDTLVILGSPRSIGLALTGLLECGRPAEAQVALVEQGTTVRQTSFTTTLGAAEAALDRLT
GQISAAVVSPNVAMRDEFSWFETKPLFGWKVLVPRTQAQAGSMIDRLAAYGAVADVVPTI
SVEPPRTPQQMEKAVRGLVTGRYEWIGFTSTNAVRAVRERFEELGLDARAFAGLKVAAVG
GVTADALREWGINPDLVPSGEQSAAGLLEVWPEFDEVLDPINRVLLPRADIATETLVAGL
RDIGWEVDDVTAYRTVRAAPPAQHVRDAIKGGDYDAVLFTSSSTVRNLVGIAGKPHPATV
VACIGPATAKTAEEHGLRVDVLAPEASALSLVDALAGHGVGLAVAAAETGQALQRPSDKR
PASRRRAR
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
gtgactcgcacacgccagccgtcagagcagacggcgacgatccccacggtcccgaccatg
ccggcgcgcgtcgccttcgtcgggtccgggccaggcgacccagggctgctgacggtccgc
gcccgcgacctcctcgccgcggccgacgtcgtcgtgctcgacggcctgatgcgcgaggag
gcggtcctcgggcacgcccgcgaggacgtgcagatcatcgacgccgcacacggcgagaac
ggtcaggagctgacgcacgcggtccgggccaagctcgtcgtcaaggccgccaagtcggtc
tccaacggcggcctcgtggtgcgcctcatggacggtgacccggcgacgttcaacggcctc
gtcgaggaggcgcgcgcctgtcgcaaggccggcatcacgttcgacgtcgtccccggtgtc
tcggccgcgaccgccgtggcgacctacgccggggtgccgctcacctccaagggcacctcg
tcggtccacgtcctcaacgcggaccagtccgggcacgacctgacccgctactgcaccgac
gacgacaccctcgtcatcctcggctcgccgcggtcgatcggcctggccctgaccggcctg
ctcgagtgtggtcgccccgcagaggcgcaggtggcgctcgtcgagcagggcaccaccgtt
cgccagacctccttcaccaccacgctcggcgccgccgaggcggcgctcgaccgcttgacc
ggtcagatctcggccgccgtcgtgtccccgaacgtcgcgatgcgtgacgagttctcctgg
ttcgagacgaagccgctcttcgggtggaaggtcctggttccccgcacccaggcccaggcc
gggtcgatgatcgaccggctcgccgcctacggcgcggtcgcggacgtcgtgccgacgatc
tcggtcgagccgccccggacgcctcagcagatggagaaggccgtccgcggcctcgtcacc
ggacgttacgagtggatcggcttcacctcgacgaacgccgttcgtgccgtgcgtgagcgg
ttcgaggagctcgggctcgacgcccgtgccttcgccgggctcaaggtcgccgccgtcggt
ggcgtcaccgccgacgccctgcgcgagtggggcatcaaccccgacctcgtgccgagcggc
gagcagtcggctgccggcctcctcgaggtgtggccggagttcgacgaggtgctcgacccg
atcaaccgggtgctcctgccgcgggccgacatcgccaccgagacgctcgtcgccggcctg
cgggacatcggctgggaggtcgacgacgtcaccgcctaccggaccgtccgtgcggcgccg
cccgcccagcacgtgcgcgacgcgatcaagggcggcgactacgacgcggtgctcttcacc
tcgagctccacggtccgcaacctcgtcggcatcgccggcaagccgcaccccgccaccgtc
gtcgcgtgcatcggcccggccacggccaagaccgcggaggagcacggcctgcgggtcgac
gtcctcgcccccgaggcatcggccctcagcctcgtcgacgccctcgccgggcacggggtg
ggtctggcggtggccgctgcggagaccggccaggcgctgcagcgccccagtgacaagcgg
cccgcgtcccgacgccgggcccgctga
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