Indicator indicator (greater honeyguide): 128977259
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Entry
128977259 CDS
T11604
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
iin Indicator indicator (greater honeyguide)
Pathway
iin04270
Vascular smooth muscle contraction
iin04350
TGF-beta signaling pathway
iin04510
Focal adhesion
iin04519
Cadherin signaling
iin04520
Adherens junction
iin04530
Tight junction
iin04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
iin00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
128977259 (ROCK1)
09133 Signaling molecules and interaction
04519 Cadherin signaling
128977259 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
128977259 (ROCK1)
04520 Adherens junction
128977259 (ROCK1)
04530 Tight junction
128977259 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
128977259 (ROCK1)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
128977259 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iin01001
]
128977259 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
iin03036
]
128977259 (ROCK1)
Enzymes [BR:
iin01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
128977259 (ROCK1)
Protein kinases [BR:
iin01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
128977259 (ROCK1)
Chromosome and associated proteins [BR:
iin03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
128977259 (ROCK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Cortex-I_coil
Pkinase_C
Par-4_C
APH
DUF1192
Motif
Other DBs
NCBI-GeneID:
128977259
NCBI-ProteinID:
XP_054250737
LinkDB
All DBs
Position
31:complement(11844399..11953985)
Genome browser
AA seq
1358 aa
AA seq
DB search
MSTGESFESRFEKIDVTLKDPKSEVNVDCLLDGLDALVYDLDFPALRKNKNIDNFLNRYK
DTVNKMRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRRVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLGVSAENSNDNRTGC
SVEKSVLENMQKMIYELEEQLHNEMQLKDEMEQKCRSSNIKLDKIMKELDEEGNQRKNLE
STVSQIEKEKIVLQHKINEYQRKIEQENEKRRNMENEVSTLKDQMEDLKKISQHSQITNE
KIAQLQKQLEEANDLLRTESDTAARLRKGNTEMSKSLSQVESLNRELQERCRVLESTKLQ
VEKDYYQLQAALESERRDRSHGSEMIGELQVRITTLQEEVKNIKNNLERVEAERKQAQDL
LNHSEKEKNNLEIDLNYKLKSLQDRLEQEVNEHKVTKARLTDKHQSLEEARSVAMCEMEK
KVKEERAAREKAENQIVQAEKQCSMLDFDLKQSQQKLEHLLEQKERLEDEVRNLSLQLEQ
ETSKRILAQSELKAQAFEADNLKGSEKQLKQEINTLLEAKRLLEFELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIDEKNKEMQRKMQELQNEKETLTTQLDLAETK
AESERLARALLEEQYFELSQESKKAASRHRQEMTDKDSIIRRLEETNSTLTKDVDLITKE
NSEISEKIKKQEEEYKMKKEEEINNIRMHYEKSINTERTLKTQAVNKLAEIMNRKDFKID
RKKANMQDLRKKEKENRKLQLELNQEKEKFNQMVVKYQKELNEMQAQLAEESTYRNELQM
QLDSKESDIEQLRRKILDLQQGMDSSSVASLQADETDGNLPESRLEGWLSVPNKGNIKRH
GWKKQYVVVSSKKILFYNDEKDKDQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKDLEVEAVQPAEKTNFINHKGHEFIPTLYHFPANCEACAKPLWHVFKPP
AALECRRCHVKCHRDHLDKKEELIAPCKVSYDVTSARDMLLLASCQDEQKKWVTHLVKKI
PKTPPSTFVRASPRTLSTRSSANQSFRKVVKNTSGKAS
NT seq
4077 nt
NT seq
+upstream
nt +downstream
nt
atgtcgacgggagaaagttttgagtctcggtttgaaaaaatcgacgtgactttaaaggac
cccaaatccgaagtgaacgtggactgtttgctggatggattagatgctcttgtatatgac
ttggattttcctgccttaagaaaaaacaaaaacattgataacttcttaaacaggtataaa
gacacagtgaataagatgagagacctgcgcatgaaagctgaagattacgaagtggtgaag
gtgattggcagaggagcgtttggggaggtgcagctggtgaggcacaagtcctccaggaga
gtgtatgctatgaagctcctcagcaagtttgagatgatcaaaagatcagattctgcattc
ttctgggaggaaagggatatcatggcctttgctaacagtccctgggttgttcagctgttt
tatgccttccaagacgaccgttacctgtacatggtgatggagtacatgcctggtggggac
ctggtgaacctgatgagcaactacgatgttccggagaagtgggcaaggttttacactgct
gaagttgtgcttgccttagatgcaattcactccatggggtttatacacagagatgtgaag
cctgataatatgctgctagataaagctggtcatttaaaactagcagattttggtacttgt
atgaagatgaacaaggaaggcatggtacgatgtgacacggccgtgggcacaccagactac
atctctcctgaggtgctgaagtcccagggcggcgatggttactatgggcgagagtgtgac
tggtggtcagttggagtcttcttgtatgagatgcttgtaggtgatacacctttctatgca
gattctttggttggcacctacagtaagattatgaaccataagaactccctgactttccct
gacgacaatgacatttccaaagaggcaaaaaacctcatctgtgcctttttaactgatagg
gaagtgaggctgggccgcaacggtgtggaagagatcaagcggcatctgttcttcaaaaat
gaccagtgggcttgggagaccctcagagacactgtagcaccagttgtgcctgacttgagc
agtgacattgacactagtaactttgatgatctggaagaagacaaaggagaggaagaaacc
tttcccataccaaaagcattcgtgggcaaccagcttccttttgttggctttacctactac
agcaaccgtcggtatttaggggtgtctgcagagaactccaacgacaacaggacaggctgc
agtgtggagaagagtgtgctggaaaatatgcagaagatgatctatgagttggaagaacaa
ctacataatgaaatgcagttgaaagatgaaatggagcagaagtgcagatcttcaaacatc
aagctagacaagataatgaaagaactggatgaagagggaaatcaaagaaagaacttggag
tcaacagtgtctcagattgagaaggaaaagattgtgctgcagcataagataaatgagtac
caaaggaagatagaacaagagaatgaaaagagacggaacatggaaaacgaagtgtccaca
ctaaaagatcagatggaagacctgaaaaaaatcagtcagcattcacagatcacaaatgag
aagatagcacagctacaaaaacaactggaagaagcaaacgatttgctgaggacagaatcg
gatactgcagcaaggttgagaaagggtaacacagagatgagcaagtcactgagccaggta
gaatcactcaacagagaactgcaggaaaggtgcagagttctagaaagcacaaaactgcag
gtggagaaagattattaccaactgcaagcagctttggagtcagaacgacgggacagaagc
catggatctgaaatgattggagaactacaggtgcggatcaccactttgcaagaagaagtg
aaaaacattaaaaataacctggagagggtggaagcagaaagaaaacaagcacaggatttg
ctgaatcactcagaaaaggaaaagaataatttagagatagatctgaactacaaactcaaa
tcattacaagaccgcttagagcaggaagtgaacgaacacaaagtgaccaaagctcggtta
acagacaaacatcagtcactagaggaggccagatcagtggcaatgtgtgaaatggaaaaa
aaagtaaaggaagaaagggcagcaagagaaaaggcagaaaatcaaatagtacaagctgaa
aagcagtgttccatgctggacttcgacctgaagcaatcccagcagaaactggagcacctt
ctggagcaaaaggagagactggaagatgaagtaaggaacctgagccttcagctggagcaa
gagacgagcaagaggatcctggcacagagtgaattgaaggcacaggcttttgaggcagat
aacctgaagggttctgagaagcagctgaaacaggaaatcaacacactgctggaagcaaag
agattgctggagtttgagttggctcagcttgctaaacaatacagaggaaatgaaggtcag
atgcgtgagctccaggaccagctggaagctgagcagtatttttcgacactttacaaaact
caggttaaggaactgaaagaggaaattgatgaaaagaataaagaaatgcaaagaaaaatg
caggaactgcaaaatgaaaaggaaacactgacgacccagctggatttagctgaaaccaaa
gctgagtctgagcggctggcacgagccctccttgaagagcagtactttgaactgagccag
gagagcaaaaaagcagcatcaagacacagacaagaaatgactgataaggacagcatcata
agaaggctggaagaaactaacagcacattaaccaaagatgttgatttaataacaaaggaa
aattcagagatcagtgaaaaaatcaagaagcaggaggaggaatacaaaatgaaaaaggag
gaggaaatcaataacattaggatgcattatgagaagagcattaacactgaaaggactctg
aagacccaggctgtcaataaactggctgagataatgaatcggaaggacttcaaaatagac
aggaagaaagctaacatgcaagatctgaggaagaaagagaaagaaaacagaaagctccag
ttggagcttaatcaagaaaaagagaaattcaatcagatggtagtgaagtaccaaaaggag
ctcaatgaaatgcaagcacaactggcagaggagtcaacatacaggaatgagctccagatg
cagctggatagcaaagagagcgacatagagcagctgcgaaggaagatcttggacctgcag
caaggaatggattccagcagtgtggccagcctgcaggccgatgagaccgacgggaacctg
ccagaatccagactggaaggctggctttcagtaccaaacaaaggcaacataaagcggcac
ggctggaagaaacagtacgttgtggtgagcagcaagaagattctgttctacaatgatgag
aaggacaaggaccagtctaatccatctatggtactagatatagataagctgttccacgtc
cgccccgtgactcaaggagatgtgtacagagctgaaacagaggagatccccaaaatattc
cagatcctctacgctaacgagggggagtgcaggaaggacctggaggtggaagcagtgcag
ccagcagagaagaccaatttcatcaatcacaaaggccatgagttcattccaacactgtac
cacttcccagccaactgtgaggcctgtgccaaacctctctggcatgtcttcaagccccct
gctgccctggaatgccgaaggtgccacgtgaagtgccacagagaccacctggataagaag
gaggagctgattgcaccctgcaaagtgagctacgatgtgacttcagcaagagatatgctg
ttactggcctcctgtcaagatgaacagaagaagtgggtgactcatttagtaaagaagatc
cccaagacaccaccatctacttttgttcgtgcttctcccaggactctgtctacaagatcc
tcagcaaatcagtcattccgaaaagttgttaaaaatacttctggaaaagctagctaa
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integrated database retrieval system
