Idiomarina loihiensis L2TR: IL0177
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Entry
IL0177 CDS
T00218
Symbol
acoA
Name
(GenBank) Probable oxoisovalerate dehydrogenase alpha and beta subunits
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
ilo
Idiomarina loihiensis L2TR
Pathway
ilo00280
Valine, leucine and isoleucine degradation
ilo00640
Propanoate metabolism
ilo00785
Lipoic acid metabolism
ilo01100
Metabolic pathways
ilo01110
Biosynthesis of secondary metabolites
ilo01210
2-Oxocarboxylic acid metabolism
Module
ilo_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ilo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
IL0177 (acoA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
IL0177 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IL0177 (acoA)
Enzymes [BR:
ilo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
IL0177 (acoA)
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Gene cluster
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AAV81020
UniProt:
Q5QWJ1
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Position
complement(189718..191904)
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AA seq
728 aa
AA seq
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MRCDIEGWQQDFIERLAQEDLPAPQSQHSNLNDSDLFALFHSQVLSRFIDIESRRLQRQG
KSFYTIGSAGHEGNAAVAAALRVTDPAFLHYRSGAFFLQRAKQLEGSNSLYDLMLSFCAS
SEDPISGGRHKVLGSLALNIPPQTSTIASHLPKAMGTAYAIGLSKRLKQAGQWPDDAIVL
CNFGDASANHSTAVGALNATGWSAYQGMPMPILYVCEDNGIGISTSTPRGWTAHQLQNYP
AIRYYYADGANVSETYAVARQAAEYIRRTRKPAILHLKTQRFFGHAGADAEVAYRSNESI
EQSFETDVLLQSAAQVIERELCTGIQLSEKAQCWLQRIRRVGTEASARPRLECAESVMAS
IVPKTLADDTQPLTSTQQQAVFAFDKRNFKKPQPLGKMINWALHEILARYQNTVVFGEDV
GKKGGVYHVTHHLFDHFGANRVVNTLLDEQSILGLAMGMAQQGFLPIPEIQFLAYVHNAE
DQIRGEAATLPFFSNGQYHNGMVIRIAGLAYQKGFGGHFHNDNSFAVFRDIPGVIVMCPS
NGHDAVLMMRQAVQLAHCQKRLVIFLEPIALYMTRDLLAEGDKGWLHEFPSATAPLPALG
EPSRYGEGDELVIITYGNGYYLSRQACSELALEKRIRILDLRYLVPLDIEKIVAAVGSAK
HILVVDECRNRGSLSEELVTALYEHRRDWQRVDRITAKDSFIPLGSAAYKVLPGKEDIIH
YLQEHLGQ
NT seq
2187 nt
NT seq
+upstream
nt +downstream
nt
atgcgttgcgatattgagggctggcaacaggactttattgagcgactggcgcaggaagat
ttacctgcgcctcaatcgcagcactcaaatttaaacgactcagatctattcgcacttttt
cacagccaggttctgagccgcttcattgatatcgaatcgcgtcgcctgcagcgccagggc
aaaagcttttataccattggcagcgctggacatgagggcaacgctgcagttgcagcggct
ttacgggtaaccgatccggcttttctgcactatcgcagcggggcattctttctacagcgt
gccaagcagttagaaggctcgaactcgctatatgacctcatgctgtcgttttgtgcctcc
agtgaagaccctatttcaggcggtcgccacaaggttttaggcagcctggcactgaatata
ccaccgcaaacttcaaccattgcttcgcacttacccaaagctatgggtaccgcctacgcc
attggactcagtaaacgcttaaagcaagctggccagtggccggatgatgccattgtgctt
tgtaactttggcgacgcctcagcaaaccactccaccgccgtaggggctctaaatgccacc
ggctggagcgcttatcagggcatgccgatgcctattctctatgtgtgtgaagacaacggc
attggtatttctacctcgactcccagaggatggacagctcatcagcttcagaattaccca
gcaatacgctactactatgcagacggcgctaatgtcagtgaaacttacgcagtagcccgt
caggcagctgagtatatcaggcgtacgcgaaagcccgctattttacatttgaagactcag
cgcttctttggtcatgccggtgccgatgcagaagttgcctatcgcagcaatgaatcgata
gaacaaagttttgaaactgacgtgcttttgcaaagtgcagcgcaagttattgagcgagaa
ctttgtaccggcattcaactctcggaaaaagcacaatgctggttacagcgcattcgtcgg
gtgggcactgaggcctctgcccgacccaggctcgaatgcgcagagtcggtcatggcttcc
attgtgccaaaaactctggccgacgatactcagccgctaaccagcacccagcaacaggcg
gtatttgcgtttgataagcgcaactttaagaagcctcaacccttaggcaaaatgattaac
tgggcattgcacgaaatattggcgcgataccagaacaccgtggtatttggtgaagatgtt
ggcaaaaaaggtggggtataccacgtgactcaccacttgttcgatcactttggcgcaaat
cgtgtggtgaataccttactagacgagcaaagcattcttggcttagccatgggcatggcg
cagcaaggctttctgcccataccagaaatacagttcctggcttacgtacataatgccgaa
gaccaaattcggggcgaagccgccactctaccctttttctctaatggtcagtaccacaac
ggtatggtcattcgtattgccggtctggcctaccagaaaggctttggcggacattttcac
aatgacaattccttcgccgtatttcgcgatattccgggcgttattgtgatgtgtccatca
aacggacacgacgccgtgctcatgatgagacaagcggttcagcttgctcactgccaaaaa
cgcttagtgatttttctggagcctattgcgctttatatgacccgcgacttgctcgcagag
ggcgacaaaggctggctgcatgagtttccgtcagctaccgcgccgttaccggctctcggc
gagccttcccgttatggcgaaggcgatgagctggttatcatcacctatggcaacggttat
tacttaagtcggcaggcgtgcagcgaactcgcgcttgaaaagcgaatccgcattcttgat
ttgcgctatttagtcccactggatattgagaaaattgtggcggccgttggctctgcgaaa
cacattctggttgtcgacgaatgccgtaaccgcggttcgttaagtgaagagctggtaacc
gctctgtacgaacatcggcgtgactggcagcgtgttgaccgtattaccgccaaagacagt
tttattcctctgggctctgccgcttataaagttctgcctggaaaagaagacattatccac
tatttacaggagcatttaggccaatga
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