Ipomoea nil (Japanese morning glory): 109180310 Help Entry 109180310         CDS       T04663                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism ini  Ipomoea nil (Japanese morning glory) Brite KEGG Orthology (KO) [BR:ini00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:ini04121]     109180310 Enzymes [BR:ini01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      109180310 Ubiquitin system [BR:ini04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     109180310 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 UBR4 ZZ zf-UBR Motif Other DBs NCBI-GeneID:  109180310 NCBI-ProteinID:  XP_019185358 LinkDB All DBs Position Un AA seq 5089 aa AA seqDB search MAEIAKLLDALSSGDDLSLRIRSDSSLRTGFQQLHAILNNALETIGDGESKLGLEAWDQS QIQAVASLALAVVHSTRSSSAEQVEPIILAVIQLAVEFALCYLEKSIRCNDDILLQSHML QLLEAALIDGAEKELDPSQPCFLNSLVDLLPSVARTDESTKWQEKLRCLLQGGRCLKEEK AVDHLLITLASDWMQPDNLNARIAGQSVRYDFNKLTTLSQHWAVAHLGCIQRIVSICKEL LEVPDLFDDKLNCTDLRKKLSFCVKALKLLGALSKDNPCADFDGKLLKSFASFTEKLTAL FRIGFEFASSSPAAVEGSFESLIMHLLEEFIQLAQAIFCNTTVFQNIQACIAAAILEKLG PEIWRYNNTAANPKPPLAYFPRVVICLLRLILDVRDRTYQLFKGLDMEYRDSQMESPSCK VNSDKVFLLKKYTLEELFKIIFPPQVQWVDNLMHLVSFLHSEGVKLRPKLERSSSTITKV SCTSESENTVCHEEEALFGDLFSEGGRSVGSADGYDQPTVASSSASNLSNMPAQAESELL TFLKNNAFAPEWCHPLYEDGCQKFNSNHISILLSIIHCQACDSDEKTSDASKLGHGQIHE LCIELLHNLLSSRALSDSLEESLVEKILMVQNGAFMYNNQTLALLAHTIIRRVDLAGSHL RSKVYEGFVNYIRDKEKVIWSDHPLLKELLESLPSLFHVEILLMAFHLSSEDEKSAQAKL VFDTLRAIGAPPTCIDSTQLSCWALLVSRLIVVLRHMLFYPRVCPSFLISDFRTKLREAS TAGLQACGGSSNVSSWPLILLDGVMSASIKEAPINNALRNQLIDIAPLPAAICRGDPAVE CFGLHWDEICFSFSLILTFWKGRKPEKVEDLVLERYIFVLCWDIPIMKSTQEHLLLFLRG TMDPDISNTEHFVYFSQAILGHTGEINDCATFSNKFLCLLHQLHDSLVPEEGGELGWDFL RCGSWLSLLLSMLTTGIWAYCKKKSITFVVPMWSEHAPRDAEFLALGESLMSNFLSPNQT AQLVNIISSLLKRYLQFYQKAFLLTFDNGQLFTGGLSPLLLFTHTGFDKCMQDEIFEKMG FKQGQLEPLHELLAKLGVSVDKMSLGIRYKVFWQSMLHGLPCHIQAPSGILLSSILSIMG IMTALDGLLKIVDAGENTCLETQVIRQIVELVLRIKCDRVFEGIHEKCETIYQNLTKDSE GSDYSCLFVIKYIEELLRNVNEREVCDSSIHECLVSKVVDIVNNLKKDPSGSGVFRFFLS VEGVSKDLYGSQRSDLLFLVESLENCTSEAVNIKVFNFFVELLSGDLCIDIKHKLQKKFL GMSLLHLSKWLEKRLLGSMIEGSSGVTCAKGTSVSLRDSTMNFITCILSPSSEFHSEELH SHLFEAMLISLDSAFMLFDSATAKCYFNLVVQLSRGENSIKALLQRIIMLIEKLAGDDNL LQGQKYIVDFLATLLSDSSSNKDVVDKLSVKSAPGQSLGVGSSASRILGSRKNADAMVLS ASQGGSASLECDATSVDEDEDDGTSDGEMGSIDKDEEEDNNSERALASKVCTFTSSGSNF MEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYSRSSRFFCDCGAGGVRGSSCQCLKP RKFTGSNNAPNRGSGNFQSFLPFTGSSDQMPDSDSDDEGIFVDSENSVRIHIPKEVQERM PILLSELDIESHVMGLCSSLLPSIISRRDSNLSRERKISLGEDKVLCYSGDILQLKKAYK SGSLDLKIKTDYSNTKELKSHLASGTLVKSLLSVSTRGRLAVGEGDKVAIFDVGQLIGQP TVAPVMADKANVKPLSKNVVRFEIVHLIFNPLAESYLAVAGYEDCQVLTVNHRGEVNDRL AIELALQGAYIKRVDWVPGSQVQLMVVTNRFVKIYDLSQDNISPMHYSTLPDDMIVDATL VMASQGRMYLIVLSEHGCLYRLELSMKGNVGAKPLKEVMQIDGRDMQPKGSSLYFSSIHR LLFLSFQDGTTLVGRVNPDATSLTEISAVLDNEADSKLRPAGLHRWKELFGDGALFVCFS SLKSNAVLAVSIGEHQVTAQNMRHSVGSTSPVVGIAAYKPLSKDKIHCLVLHDDGSLQIY SHVPAGTDTGISAITDKVKKLGPGILNSKAYGGAKPEFPLDFFEKTICITQDVKLSSEAI KNGDSEGVKQTLASEDGFLESPSSGGFKITVSNSNSDIVMVGLRLHVGNTSANHIPSEVT VFQRVIKLDEGMRSWYDIPFTVAESLLADEEFTIGVGPTFSGSALPRIDSLEVYGQAKDE FGWKEKMNDVLDMEARMLGSSSWAAGSGRKSRATQSAPLQEQVMADGLKVLSSIYALCQP QGCSKVEDVKLELSKLKCKQLLEAVFESDREPLLQSAACRVLRAVFPKREIYHQVKDTMR LTGVVKSAAMLSSKLGIGGTTAGWIIEEFTSQMCAVSKIALRRRSNLASFIEMNGSEVVD GLMQVLWGILYIEQPDTQTMNNIVVSSVELIYCYAECLALHGKDGGRSSVAPAVSLFKKL LFSTNEAVQTSSSLAISSRLLQVPFPKQTMLGTDDADNPSSVPSRADPSTAASGNTQVMV EEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFDLCETCYEVLDAARLPPPHSRDHPMT AIPIEVETFGDGNEIHFTTDDLSDSGLLPVASDVCAQSSAPSIHELEPNESGEFSASLLD PVTISASKRAVNSLLLSELLEQLKGWMETTSGVQAIPVMQLFYRLASAVGGPFADGSEPE SIDLEKLIKWFLEEINISKPLAAKNRIPFGEVTILVFMFFTLMLRNWHQPGSDGSATKSG STTESQDKSVSQVLASTSMPASSTLDGQEKNDFISHLLRACGTLRHQPFVNYLMDILQQL VSVFKSPSVNTDASYGLNAASGCGALLIIRREVPAGNFSPFFSDSYAKSHRADIFADYHR LLLENTFRLLYSMIRPEKHEKGGEKEKFHKVSLSKDLKLDGYQDVLCSYINNPHTTFVRR YARRLFLHLCGSKTHYYSVRDSWQFSNDLKKLYKHVNKSGGFESTISYERNAKIVKSLST MAEVALSRPRNWQKYCLRHADVLPFLVNVVFYFGEECVIQTLKLLNLAFYTGKDNNHTSQ KTEGGDIGGAASKTGVQPLESKKKKKGEDSESSSEKTHFDMEAVVDVLVGKGGDILRQFI DCFLLEWNSSSVRMEAKCVLFGIWHHGDQSFKEALLTALLQKIKFLPMYGQNITEYTELL TFLLGKVPENSSKQQCAEIVDKCLTNDVIRCIFDTLHSQNELLANHPNSRIYNTLSGLVE FDGYYLESEPCVACSSPEVPYSRMKLESLKSETKFTDNRIIVKCTGSYTIQSVIMNVHDA RKSKSVKVLNLYYNNRPVADLSELKNNWSLWKRAKSCHLAFNQTELKVDFPIPITACNFM IELDSFYENLQALSLEPLQCPRCSRPVTEKHGICSNCHENAYQCRQCRNINYENLDSFLC NECGYSKYGRFEFNFMAKPSFTFDSMENDEDMKRGLAAIEAESENAHRRYQQLLGFKKPL HKIVSSIGENEMDSQQKDSVQQMMVSLPGPSCKINRKIALLGVLYGEKCKAAFDSVSKSV QTLQGLRRVLMNYLHQKQSGNATATSRFVVSRSPNSCYGCASTFVTQCVEILQVLSKHPT SKKQLVAAGILSELFENNIHQGPKTARVQARAALCAFSEGDVNAVAELNTLMQKKVMYCL EHHRSIDIALATREELSLLSDVCSLADEFWESRLRVVFQLLFSSIKIGAKHPAISEHVIL PCLRIISQACTPPKPDAAEKEHGIGKPAQGTQVKEENSGNVSGSSSLVNGSKLVTESSEK SWSNSQKMQDIQLLSYSEWEKGASYLDFVRRQYKVSQAAKGSQRSRSQSQRQDYLALKYA LRWKRCACKSARSDMSSFELGSWVSELILSACSQSIRSEMCMLISLLCGQSSMRRYRLLN LLMSLLPATLSAGENAAEYFELLFKMIDSEDACLFLTVRGCLKTICKLITQELSNVESLE RSLHVDISQGFILHKLIELLGKFLDVPNIRSRFMRDHLLSEVLEALIVIRGLVVQKTKLI NDCNKLLKDLLDSLLLESNENKRQFIQACISGLQIHGDESKGRTSMFILEQLCNLISPSK PEPTYHLILNKAHTQEEFIRGSMTKNPYSSTEIGPLMRDVKNKICQQLDLLGLIEDDYGM ELLVAGNIISLDLSIAQVYELVWKKSSSQSSNTVAGTTLISSTAAASARDCPPMTVTYRL QGLDGEATEPMIKELDEDREETQDPEVEFAIAGAVRECGGLEILLGMVQRLQDDFKSNQE QLVAVLNLLMLCCKIRENRKALLRLGALGLLLETARRAFLVDAMESAEGILLIVESLTLE ANESDGISITPGVLTVSSEERGGGEQAKKIVLLFLERLSHPSGLKKSNKQQRNTEMVARI LPYLTYGEPAAMEVLIQHFEPFLQNWIEFDRLQRLYEDNEKDDSIAQQASKQKFTLENFV RVSESLKTSSCGERLKDIILEKGITGAAVRHLKESFPITGQVGFKSTAEWAVGLKLPSVP LILSMLRGLSMGHLATQRCIDEGGILHLLHALEGVAGENEIGARAENLLDTLSDKEGKGD GFLAEKVCQLRHATRDEMRRRALKKREQLLKGLGMRQELASDGGERIVVAQPVLEGLEDV EEEEDGLACMVCREGYRLRPTDLLGVYTYSKRVNLGVGTSSNARGDCVYTTVSHFNIIHF QCHQEAKRADAALKNPKKEWDGAALRNNETLCNNLFPLRGASVPIGQYIRYVDQYWEYLN ILGRADGSRLRLLTYDIVLMLARFATGASFSTDSRGGGKESNARFLPFMIQMARHLLDHD SSQRHTMAKSISTYLASPTSESKSPTTSGTPPSAAAAGTEETVQFMMVSSLLSESYESWL QHRFAFLQRGIYHAYMQRTHGRSMQRFSPNLSGSTSGSSSETSGSNDLLSIIQPMLVYTG LIEQLQCFFKVKKSSSTATTQTQGTSKDMEGEDESKKLEAWEMVMKERLLNVKEMVGFSK ELLSWLDDMISAADLQEAFDILGVLSDVLSGGVTSCEDFVRAAIDSGKN NT seq 15270 nt NT seq  +upstreamnt  +downstreamnt atggccgagatcgccaagcttctcgatgctctctcctccggagacgatctgtctctgagg attcgttccgattcctccctcaggacaggcttccagcaactccacgcgatcctcaacaac gccctcgagacgatcggtgatggggagagtaagctagggctcgaagcatgggaccagtct cagattcaagccgtcgcttcgttggctctcgccgtcgttcactccactcgatcttcttct gctgagcaagtggaacctataattctggccgttattcaattagcggttgagtttgcactg tgttatctggagaaatcaatccgttgcaatgacgatatactactccagagtcacatgttg caactgctggaagcagcacttattgatggggcagagaaagagttggatccttcacagcca tgctttctaaatagtcttgtggatctgttgccatcagttgctagaaccgatgaaagtact aagtggcaggagaaacttagatgcttgcttcaagggggaagatgcttaaaggaagagaag gctgttgatcaccttctaatcacattagcctctgattggatgcaacctgacaatttgaat gcaaggatagctgggcagtctgttcggtatgattttaacaagttgaccactctgtctcag cactgggctgttgctcatctgggatgtattcagcgtattgtttccatctgcaaagagctt ttagaagttccagatttgtttgatgataaattgaactgcacagatttgaggaagaaattg tctttttgtgttaaagcattgaaattactgggagctctctcaaaagataatccatgcgct gactttgatggcaaattgttgaaatcctttgcttcgttcactgaaaagttgacagccttg ttcaggataggttttgaatttgcaagcagcagccctgctgctgttgagggtagttttgag agtctcataatgcatttgttggaagagttcattcaacttgcacaggcaattttttgtaat actactgtgtttcagaacatccaagcatgtatagcagcggctattttggaaaaattgggt ccagaaatatggaggtacaacaatactgctgccaatcccaagcctcctttggcttacttc cctcgagttgttatttgtcttttgagactgattttagatgttagggatcgaacatatcag ctatttaagggtttagacatggaatatagagactctcaaatggagtctccatcatgcaag gtaaattcagacaaggtatttctgctgaagaagtacacacttgaggagctattcaaaata atattcccccctcaagttcaatgggtagataatctgatgcatctcgtttctttccttcac tctgaaggtgtcaaattgagaccaaaactggaaaggtcatcttccaccataacaaaagtg tcttgtacatctgaatcagaaaacactgtttgccatgaagaagaagccctctttggtgac cttttttcagaaggtggtcgctcagtgggttctgcagatggatatgatcaacctactgtt gcatctagttctgcttccaacttgagcaatatgccggctcaagctgaaagtgaactgctc acttttcttaagaataatgcctttgctcctgaatggtgtcatcctttgtatgaagatggg tgccaaaaattcaatagcaaccacataagtattttgctatctataattcattgccaagcc tgtgattctgatgaaaaaacttctgatgcctctaaacttgggcatggacaaattcatgaa ctgtgcattgagctgctgcataatctcctctcctctcgtgctttgtctgattcacttgaa gaatcccttgttgagaaaatcctgatggttcagaatggtgcatttatgtacaacaaccaa acactggccttacttgcccacacaattatacgtcgggtggatttggcaggtagtcacttg aggtccaaagtttatgaaggttttgtcaattatattcgtgacaaggaaaaagtgatctgg tcagaccatcctctgcttaaggagcttttggagagtcttccttctttgtttcatgttgag attcttctaatggcatttcatttatcatctgaagatgaaaagtctgcacaggcaaaatta gtatttgatacccttagagctattggtgctcctcctacttgtattgatagcacacagttg tcatgttgggcattacttgtttcacgtttgatcgtggtcctccgtcatatgctattttac cctcgtgtttgcccttcatttttgatttcagacttcagaaccaagttgagggaagcctcc acagcagggttacaggcttgtggtggctcttctaatgtttcatcttggcctttgattttg ttggatggcgtaatgagtgcttcaattaaagaagcacctatcaacaatgctttgcggaat caactaattgatattgcacctcttcctgctgctatatgtagaggtgatccagcagttgaa tgttttggtttgcattgggatgaaatatgtttctctttctccttgatactaacattctgg aaaggtagaaaaccagaaaaggtggaggatctagttcttgaaagatatatatttgtgctt tgttgggatattccaatcatgaaatctacacaagagcatctgctgcttttcttacgtggc acaatggatcctgacatctcaaatactgagcattttgtgtatttcagtcaagccattttg ggtcatactggtgaaatcaatgattgtgctactttttctaataagtttttgtgcttactt catcagttgcatgattctcttgtaccagaggaaggtggggaactgggttgggatttcttg aggtgtggatcttggttgtcattgttactgtccatgctcaccactggcatctgggcttac tgcaagaaaaagtccatcacatttgttgtccctatgtggtcagagcatgcacctcgagat gcagaatttttggctttaggtgaaagccttatgtcaaattttttaagtcccaatcaaact gcacagcttgtaaatattatttcatctttgttgaagagatacttgcaattttatcagaag gctttccttttgacatttgataatggacaacttttcacgggtgggctgtcaccactcttg cttttcactcatactggctttgataagtgcatgcaagatgagatctttgaaaagatggga tttaaacaaggccaattggagcctcttcacgaactcctggccaagttgggtgtaagtgtt gacaaaatgtctttggggattcgatataaggttttctggcaatctatgttgcatgggttg ccttgtcatattcaagcccctagtggaatcctcctctcctctattcttagtatcatgggt atcatgactgctcttgatggattgctgaaaattgttgatgctggagaaaatacctgtttg gagacacaggttatccgtcagatagttgaattggtattacgaatcaagtgtgacagggtt tttgaagggattcatgagaagtgtgaaactatttatcaaaacctgaccaaagactctgag ggatctgattatagctgtttatttgtgataaaatacattgaagaacttttaaggaatgtc aatgagagagaagtttgtgatagtagtatccatgaatgcttggtttccaaggttgtagac attgttaacaacctgaagaaagatccttcaggaagtggggttttcaggtttttcctatct gtggagggtgtctctaaggatctctatggctcacaacgtagtgatttattgttcctggtt gagtcactggagaattgcacctctgaagctgtcaatataaaggttttcaacttttttgtt gagctcttatctggggacttgtgtattgacattaaacacaaattacagaagaaattcctt ggtatgagtttgcttcacctgtcaaaatggcttgaaaagaggctcctaggatccatgatt gaagggtcaagtggtgttacatgtgcaaaaggaacttcggtctctttaagagattcaacc atgaatttcattacttgcatcctttccccgtcttctgaatttcattctgaagaactacac agtcacttatttgaagctatgctaatttcacttgacagtgcctttatgctgtttgattcc gctactgcaaaatgttatttcaatttggtagttcagctttccagaggggagaattcaatc aaggcactcctgcagcggatcataatgctgatagagaaactggctggtgatgacaatctg cttcaggggcagaaatatattgttgactttctggcaactcttctaagtgatagcagctct aacaaagatgtggttgataaattgtctgtgaagtctgctcctggccaaagtttgggggtg ggatcttcagcctctagaatcctaggttccaggaagaatgctgatgctatggtcctttct gccagtcaaggtgggtcagcatccctcgagtgtgatgcaacttctgtggatgaagatgag gatgatggaacatctgatggggaaatgggtagcattgacaaggatgaagaggaagataac aacagtgagagagctcttgcctcaaaagtttgcacgtttacttccagcggcagtaatttt atggaacaacattggtacttctgctacacgtgtgatctgacagtctccaaaggctgctgt tctgtgtgtgcaaaagtttgccatcgtggtcatcgtgtagtctattctcgctctagtcgc tttttctgtgactgtggagcaggaggtgtacgtggtagcagctgtcagtgcttgaagcct cgaaaatttactggcagtaataatgctccaaatcgtggttctggcaacttccagtctttt ttgccttttacaggaagcagcgatcaaatgcctgatagtgattcagatgatgagggtatt tttgtggactcagagaattcagttaggatacacattccaaaagaggtccaagagaggatg ccaatcttattgagtgaactagacattgaatctcatgtaatgggactctgctcttcattg ttgccttctattataagcagaagagattccaacctgtcaagagagagaaaaatcagcttg ggtgaagataaagtgctttgttacagtggagatattttgcaattgaagaaagcctacaaa agtggatctctagacttgaagataaagacagattattccaataccaaggagctgaaatcc catctagctagtggtactcttgttaaatcattactcagtgtcagtacccgaggccgactt gctgttggagaaggtgacaaggtagctatatttgatgttgggcagcttattggacaaccc actgttgcacctgtgatggctgacaaggccaatgtgaaacccctttctaagaatgttgtc cgctttgagattgtgcatctcattttcaatccattagcagagagttaccttgctgttgct ggctatgaggactgccaggttcttactgtaaatcatcgaggtgaagtgaatgatcgttta gctattgaacttgctctgcaaggtgcatatattaaacgtgtggactgggttcctggatct caggttcagctcatggttgtcaccaacagatttgttaaaatatatgatttatcccaggat aacattagtcctatgcactactcaacattgcctgatgacatgattgttgatgcaaccctt gtcatggcttcccaaggtaggatgtatcttattgtcctgtcagagcatggttgcttatat aggttagaattgtcaatgaaaggaaatgttggggccaagccattgaaagaagtaatgcaa atagatggcagagacatgcaaccaaaaggctcttcattatatttttcatcaattcatagg ttactttttctgtcatttcaagatggtaccactttggttggccgagtaaatccggatgca acatccttgactgagatatctgctgtattggataatgaagctgacagcaaactccggcca gcaggattgcaccgttggaaagagttatttggtgatggtgctttatttgtatgcttttca agtttgaaatcaaatgctgtccttgctgtttccataggcgaacatcaagtcactgcacag aacatgcgacattcagtgggctctacatctcctgtagttggtattgctgcttacaagcct ttatcaaaagacaaaatacattgtcttgttttgcatgatgatggaagccttcagatatac tcacatgttccagccggtacagacactggcattagtgcaattactgataaggttaaaaag ttgggccctggtatccttaacagtaaagcatatggtggtgcgaaacccgaattcccactg gatttttttgagaagaccatatgcattacacaagatgtcaaactaagcagtgaggcaatc aagaatggtgactctgaaggagtaaaacagacactagcttctgaagatgggttcttggag agccctagttctggtggatttaagatcactgtttctaattcaaattccgacattgtgatg gttggtctacgcttgcatgtgggtaacacatcagcaaaccatataccctctgaagtcaca gttttccagagagtaataaaattagacgagggaatgaggtcttggtatgatattccgttc acagtggccgaatcactgcttgctgatgaggagttcacaattggtgttggacctacattc agtggatctgcattaccacgtatcgattcattagaagtttatggccaagctaaggatgaa tttggatggaaagagaagatgaatgatgttctagacatggaagctcgtatgcttggctct agctcatgggctgctggatcaggtaggaagtctcgcgcaacacagtctgctcctcttcag gaacaggtaatggctgatggcctcaaggttttatcaagtatttatgcattgtgccaacca caagggtgctcaaaagttgaggatgttaagctggagcttagcaaactcaagtgcaagcag ttgctggaagctgtgtttgagagtgacagagaacctttgttacagtctgctgcctgtcgt gtcctgcgggctgtctttccaaaaagggagatctatcaccaagttaaggacacaatgcgt cttacaggagttgttaaatctgctgcgatgctttcttcaaagctgggaattggggggact actgctggatggattattgaggaatttacttcgcagatgtgtgctgtttccaagattgct cttcgtcgtcgctcaaacttggctagcttcattgagatgaatggttcggaagtggttgat gggcttatgcaagttttgtggggaattttgtacatagagcagcccgacacgcaaactatg aataatatagttgtatcttccgtagaactgatctactgttatgctgagtgtctagcattg catgggaaagatggaggcagaagttctgttgcacctgcagtttcattgtttaagaagctc ctgttttcaaccaatgaggctgtacaaacatccagcagtttggctatatcttcgagattg ttacaggttcctttcccaaagcagaccatgttaggtacagatgatgctgacaacccttca tctgttccaagtcgagctgatccttccactgcagccagtgggaatactcaagtcatggtc gaagaagattccattacttcatcagtccaatactgttgtgatggctgttccactgttcct atcctcaggcgaagatggcactgtactgtttgtcctgattttgatttatgtgagacatgt tatgaagtacttgatgcagccagacttcctccaccacactctagagatcaccctatgaca gcaattccaattgaagtggaaacatttggggatggcaatgaaattcatttcactactgat gatttaagtgactctggtctgttgcctgttgcatctgatgtttgtgcgcagagttctgct ccatctatccatgagttggaaccaaatgaatctggagagttttcagcgtcactacttgac cctgtaacgatttctgcatcgaaaagggctgttaactcactgcttctttctgagctcctt gaacaactgaaaggatggatggaaactacctctggagttcaggctattcctgttatgcag cttttctacagattggcatctgctgtgggtggaccgtttgctgacggttcagagcctgaa agtatagatttggagaaattaataaaatggtttttggaggagataaatatcagcaaacct cttgcagccaaaaacaggataccttttggagaagttacgattctagtatttatgtttttc actttaatgttgcgaaactggcaccagccaggaagtgatggctctgctactaaatctggg agtacaactgaatcacaagacaaaagtgtgtcacaagttttggcttctacatcaatgcct gcctcatcaacattggatgggcaagagaaaaatgatttcatttctcatctccttcgagct tgtggaacccttaggcatcaaccatttgttaattatttgatggatattctgcagcagctg gtcagtgtttttaagtcaccatctgttaacactgatgcatcttatggtctgaatgctgct tctggatgcggtgcattattaataatacggagagaggtaccagcgggtaatttctcacca ttcttttctgactcctatgccaaatcacatcgtgcagatatatttgcagactaccataga ctcttgctggaaaatactttccgacttctttacagtatgatacgaccagaaaagcatgag aagggtggggagaaagagaagttccacaaagtgtctctgagcaaggatttgaagctggat ggatatcaggatgtcctctgcagctacatcaataatcctcatacaacttttgttagaagg tatgcaaggaggcttttcttgcatctatgtggtagtaagacacactactacagtgttaga gactcttggcagttctcgaacgatttgaagaagctctataagcatgtaaacaaatctggt ggctttgaaagtactatctcatatgagaggaatgccaagatagttaagtccctatccacc atggctgaagttgctttatctcgacctcgaaactggcagaagtactgtttaaggcatgct gatgttctacctttccttgtgaatgtggttttctattttggggaggaatgtgtaattcag acattaaaacttctgaatttggccttctatactggaaaggataataatcacacttcgcaa aaaactgaaggaggggatataggtggagctgcaagcaagacaggtgtacaaccacttgaa tctaagaagaagaagaagggagaagatagtgagtccagttctgaaaaaactcactttgat atggaagcagtggtggatgtccttgttggcaagggtggtgatatattgaggcagtttatt gactgttttttattggaatggaattcaagctctgtgcgtatggaagccaaatgtgtcttg tttggtatctggcatcatggagatcagtctttcaaagaggcattgttaacagcacttctg cagaaaataaaatttttgcccatgtatggacagaacatcactgaatatactgaacttctc accttcttgttggggaaggtaccggagaacagttcaaagcaacaatgtgctgaaattgtt gacaaatgcttgaccaatgatgtaattaggtgtatatttgacacacttcactcccaaaat gagctgttggctaatcatcctaattcgcgaatatacaacactttaagtggtctggtggaa tttgatggttactatcttgagagtgagccttgtgttgcctgcagctcccctgaggtgccg tatagcaggatgaaactagaaagcttgaaatccgaaacgaagttcactgacaatcggatc atagtgaaatgtactggtagctatacaattcagagtgtgatcatgaatgtccatgacgct cgcaagtccaagtcagtgaaagtcctgaacctttattacaacaacaggcctgtggctgac ctttcagagttgaaaaataattggtcattgtggaagcgtgcaaagagctgtcatcttgcc tttaatcagacagagctaaaagtggattttccaataccaatcactgcatgtaatttcatg attgagctggactctttctatgaaaatcttcaagctttatcccttgagcctctgcagtgt cctcgttgcagtcgacctgttactgaaaagcatggtatttgcagtaattgtcatgagaat gcatatcagtgcagacagtgccgtaatatcaattatgaaaatcttgattcatttttatgc aatgaatgtggatacagcaaatatggtagatttgaattcaattttatggcaaagccaagt ttcacttttgatagcatggaaaatgatgaagatatgaagaggggcttggcagcaatagag gcggaatctgaaaatgctcataggaggtatcagcagctcttaggtttcaagaaacctttg cacaagatagtatcaagtattggcgagaatgagatggactcgcaacagaaggattctgtt cagcaaatgatggtctctttacctggaccttcctgtaagataaaccgtaaaattgctctt cttggtgtcttgtatggtgagaaatgcaaagcagcatttgattctgtgagcaaaagtgtt cagactttacaaggtttgcggcgggttttaatgaactacttgcatcaaaaacaatctggg aatgctactgcaacctccagatttgttgtttcaaggtcaccaaacagttgctatggatgt gcttctacttttgtcactcaatgtgtggaaatactacaggtactatcaaagcacccaaca tccaagaagcaacttgttgcagcaggtattttgtcagagctctttgaaaataacattcat cagggccctaaaacagctcgtgtccaagcaagggctgccctttgtgccttctcagaaggt gatgtgaatgcagtagctgagttgaacacactaatgcagaaaaaggtcatgtactgtctt gagcatcatcgttccattgacattgctttggccacaagagaagagttgtcactattatct gatgtgtgttctttggcagatgaattttgggaatcaagactgagagttgtcttccagtta ttattttcttctataaaaataggggctaaacatcctgctatatctgagcatgttattctt ccatgcctacggattatatcccaggcatgcactcctccaaagcctgatgcagctgagaaa gagcatgggataggaaaacctgctcagggtacacaagtgaaagaagaaaacagtggaaat gtttctggatctagtagccttgtcaatggaagcaaacttgtaacagaatcatctgagaag agttggagtaattctcaaaaaatgcaagatatacagttgctaagttattcggaatgggaa aaaggtgcttcgtatcttgattttgtaaggcggcaatataaggtgtctcaggcagcaaaa ggcagtcaaagatctcgatctcaatctcaaaggcaggattacttggccttgaagtatgct ctaagatggaaacgatgtgcttgtaaatcagctcgaagtgatatgtcatcttttgagctt ggttcctgggtttcagaacttatattgagtgcatgttcacagtctataaggtctgaaatg tgcatgctgattagtttgctgtgtggccaaagttcaatgagacggtatcgcttgctgaac ctgcttatgtctctgctcccagcaactctttctgctggtgaaaatgctgctgaatatttt gaattactttttaagatgatagactcagaagatgcttgccttttcttgactgttcgtgga tgtttgaaaacaatatgcaagttgataacccaagaactgagtaatgttgaatccttagag aggagtttgcatgttgacatatcacagggcttcattcttcacaagcttatagagctcctt ggcaaatttttggatgttcctaatatcagatccagatttatgagagatcatttattgtct gaggtccttgaagctttaattgtcattagagggttggttgtgcagaagacaaagctgatt aatgactgtaataaacttctgaaagatcttttagatagtcttctgcttgagagtaacgaa aataaacgtcagttcattcaagcatgcatctctggtcttcaaattcatggagatgagagt aaaggaagaacttctatgtttatattggagcagctctgcaacttgatcagcccatcaaaa ccggaacctacttatcacttgatcttgaacaaggcacatacacaagaagaatttatcagg ggatcgatgaccaaaaatccttattcgagtactgagattggccccctgatgcgtgatgtt aaaaacaagatttgccaacagttggatctcttgggtcttattgaagatgactatggcatg gagctgctagtagctggaaatataatatctcttgatttgagcattgcccaagtttatgag ctagtgtggaagaagtccagcagtcagtcttcaaacacagtagctgggacaacattgatt tcttctactgctgctgcatctgccagagattgtcctccaatgacagtgacttaccggtta cagggtctagatggtgaagccactgaacccatgattaaagaactggatgaagacagagag gaaacccaggatccagaggtagagtttgccatagctggtgcagtccgggaatgtggtgga cttgaaatccttttagggatggtccagcgtttgcaagatgatttcaagtctaaccaagag cagctagttgcagttcttaatctactcatgctatgctgcaagataagagaaaacagaaaa gcactgctaaggctgggagctttgggattactacttgaaacagcacggcgtgctttcctt gtggatgccatggagtcagctgagggcatcctattgattgtggagagtttaacattagaa gcaaatgaaagtgatggcattagcattactccaggcgtccttacagtttcaagtgaagaa agaggtggcggtgaacaggccaaaaaaatagttctcctattcctggagagattatctcat ccatctggacttaaaaaatcaaacaaacagcaaaggaacacagagatggttgcaagaatt ttgccttatttgacctatggagaacctgcagcaatggaagtgcttatccagcattttgaa ccatttttacagaattggattgaatttgataggctgcaaaggctttatgaagacaatgaa aaggatgatagtattgctcagcaagcttccaaacagaaatttacgctggaaaattttgta agagtttcagaatcactcaaaacaagttcctgtggggaaaggctgaaagatatcatattg gagaaggggattactggagctgctgttagacatctaaaagagagctttccaattactgga caggtgggctttaaatctactgcagagtgggctgttggcttaaaactgccatctgttcca cttatattgtccatgctaaggggtttgtcaatgggacatttggcaactcagagatgtatt gatgaagggggaattttacatttgctccatgctttggagggtgtggctggtgaaaatgag attggtgcaagggctgaaaacttgttggacacgctttctgataaagagggaaaaggggat ggcttcttggctgagaaggtttgtcagttaagacatgcaacacgagatgagatgaggcgt cgtgctctaaagaagagggaacagttacttaagggacttgggatgcgacaagaactggct tcagatggtggtgagcgaattgtggttgctcaaccagtcttggaaggcttagaagatgtg gaggaagaggaggatgggttagcttgcatggtgtgccgtgaagggtaccgcttgcgtcct actgacttactgggtgtttacacatatagtaaaagggtgaaccttggtgttggaacttca tcaaatgctcgtggagactgtgtttacacaacggttagccattttaacattatacacttc caatgccatcaggaagctaaaagagcagatgctgcactaaagaatccgaaaaaggagtgg gatggcgcagcacttagaaacaatgagaccctttgcaacaatcttttcccattaaggggg gcatcagtcccaattgggcagtatatacgttatgtggaccagtactgggaatacctcaat attctggggcgtgctgatggaagtcggctccgactcttaacctatgacattgttctgatg cttgctcgatttgcaacgggtgcttcatttagtacagatagcagaggtgggggaaaggaa agtaatgctcggtttttgcctttcatgatacaaatggctcgtcaccttttggaccacgat tcttctcagcggcataccatggccaagtctatctcaacttatttggcttctccaacttca gaatccaaaagccctacaacatctggaactccaccttctgctgctgctgctggaacagaa gaaactgtccagttcatgatggttagctcgcttctttcagaatcgtatgaatcatggttg cagcatcgttttgccttcttgcagcgtggaatataccatgcatatatgcagcgcactcat ggtcgctccatgcagcgtttctcacctaatctctctggtagtacaagtggaagttctagt gaaactagtggatcaaacgacttgctgtcaatcatccaaccaatgcttgtatataccggt ttgattgaacaactacagtgtttcttcaaggtaaagaaatcatccagtacagccacaacc caaacccagggaacctccaaagacatggagggggaggatgagagcaaaaagttggaagct tgggagatggtgatgaaagagagactcttaaatgtaaaggagatggtgggcttctccaag gaattgttgtcatggcttgacgacatgatttctgctgcagatttacaggaagcattcgac atcctcggtgttctgagtgacgtgctttctggtggtgtcacaagctgtgaggattttgtg cgtgctgcaattgattctggtaaaaactga

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