Ictalurus punctatus (channel catfish): 108256661 Help Entry 108256661         CDS       T04658                                  Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism ipu  Ictalurus punctatus (channel catfish) Pathway ipu03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:ipu00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     108256661  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:ipu03009]     108256661 Ribosome biogenesis [BR:ipu03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     108256661 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 AAA_22 TsaE nSTAND3 ABC_tran Sigma54_activat AAA_14 Sigma54_activ_2 AAA_18 AAA_2 AAA_6 AAA_29 DUF815 Dynein_heavy AAA_25 MDN1_4th bpMoxR AAA_8 PduV-EutP VWA_2 VWA TniB ATPase Motif Other DBs NCBI-GeneID:  108256661 NCBI-ProteinID:  XP_053542579 UniProt:  A0A9F7TME5 LinkDB All DBs Position 2:4148212..4191120 Genome browser AA seq 5532 aa AA seqDB search METLELSLASLATISRHVEKSHGELSKYLTKQIWSQQDRQAILCCLTQLLIEKEYTLLIA RHLRPLVLDLLERNAERIKKDVRLNHDLHERLCVALSKLLSVSPDAQAFAARYFTSAPPV FQRLFFTSEEAASIHYGPRRMKLRDLMGATLRFLQSDCEKFRVLWDWSACISQLLTSDVM VRGYTAQCLALVSHMTDNQKTIFLRKVLSSDEILHLKMKSLEETQQLEVERALVLANQGS VMWQLEKGNKLTKGQMGSGDLSQGITAVCGVILARLTPRQEEQTSLKTLVLVDSTCRNLR RLAMAVASQRPVLLEGPIGCGKTALVEYLAAATGHVKSPNILKVQLGDQTDSKMLLGMYR CTDIPGKFVWQPGSLTQAVSKGYWILLEDIDHAPLDVISVLLPLMENKKLTIPGREDCIQ VAPGFQFFATRRIFYSGGVWHRPQSTHAALLDKYWNKLQIGNMTREELKQVVLDKFPNLA VVVDRLLDIYCQLTGDKHHVAVAAPGPQNPSEDRPTMLEGRGLSLRDLLKWCERIYVNFD SSSSNTAQNVFLEALDCFTAMQSKAESRLKLAEVIGSKLNISKEKAQHFCQMYQPAISIT ELEVTVGRAMLLRKQSDAVRLDVDKQTFAATRPSSVLLEQLAVCVTKGEPVLLVGETGTG KTSTVQYLAGLTGHKLRVINMNQQSDTADLLGGYKPVDHKLILLPLREAFEDLFSQTYSR KQNITFLGHVQTCFRGKRWQDLLKLMDHVCKSALTKELQDKPNAALLQQQWEALALRLSQ TQEQIRARESALVFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSGLLEGSAGSLVL LDRGDTEPLVRHSDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEELESEGDLRVLVSD YLKGLNLNRSTIHGIISFYLAIRKEASSRLVDGTGHKPHYSLRTLCRALKYVATNPCYNV QRSLFEGFCLSFLTQLDRSSHPVVEKLVHQYILGGNIKCLKQPIPEPRSRGCLQIEGYWL CQGDMDPALDPSYILTPSVRLNLRDLARVVAAGIHPVLIQGETSVGKTSLVRWLAAATGN QCVRINNHEHTDIQEYIGCYSSDEHGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEA LNRLLDDNRELFVAETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDEL PSEELETILHQRCSLPPSYCTKLVKVMQNLQSLRRGSSVFAGKHGYITLRDLFRWAERYR LEEQTDSSRDWLQHLADDGYMLLAGRVRKPEEALTIQNVLEKHFKRTVNPDALFSEDQVN TQFSPFVASLAGMPEEFGHVVWTQGMRRLAVLVGRALRFGESVLLVGDTGCGKTTICQLF AALAGLKFFAVNCHLHMETSDFLGGLRPVRHIGTGQADAEDGRLFEWRDGPLVLAMKQEG VFLMDEISLADDSVLERLNSVLETEKSLVLAEKGSSDDDDVELIIAGKKFRLVATMNPGG DFGKKELSPALRNRFTEIWCPQSNSRGDLMKIVQHNLRAGLSLDQHDHQGKDVAEVMLDF IDWLTNQEFGRRCILSVRDILSWVDFLNAVCEKDEDRDESSFMGLEEIEEPEWDQRLDTV TAFIHAACLVYIDGIGSGTTVSAAENVAAARKACLAFLETKLRRITKLDEKMQEALRVYD TSLVREPRWGDDFFGIEPFYVVADPESESRGLLDYALGAGTTAVNTMRILRALKLQRPIL LEGSPGVGKTSLVAALAKASGNQLIRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGPL LAALKAGHWIVLDELNLASQSVLEGLNACFDHRAEIYIPELSIRFQVRHEKTKIFGCQNP FTQGGGRKGLPKSFLNRFTQVYVDQLSSEDMQFIGNSIFPNISEQIISKMVQFSNKLVTE VAVERKWGQKGGPWEFNLRDLFRWCQLMQADQSPAFYNPGQHVGLVYADRMRTEADKAQV LSVFRKVFAEDFEPHLGSRQFHITPLNLQVGSSVLQRSGGAPVVLDPPLSITHQALRPLE SLMKCVKMGWMAILVGPSASGKSSLVHLLALLTGHRLRVMAMNSAMDTTELLGGFEQVDI IRPWQQVLESMDYVVAMVTRRGLMSLDGGVQDTEFLLSTWSTFRRWLKDEGLDTADGTVT FEALNKLEVIIVLLHKLNTKLKVFTDMSKLQMDFTLLKERLAQMEDGWSHGGFEWLDGTL VQALQAGDWLLMDNVNFCSPSVLDRLNALLEPGGSLTINERGVIDGTTPSITPHPNFRLF LTMDPTHGEISRAMRNRGVEIYVPGENEGACWDSLDLKTILHTLGVTGDCVCDLLMTVHS EIKSAIWDSPASSVSSLLHAAALLSGQLQRGVDLPSALLQACGEAYALCQRTSANQKLAQ ELIERQLAVLDSEEWGSGLVCAGVWPDRVPSALQSTEDSCFSSVQRDGQVLLYCLNTLSL HSKRSRPLILTDLQRAMQSGAALETLQFPPEGGSAGDRIRDAQQLLPTAVRILTEGASHS DWVLRTSWLSHLAKSYKHVPEAALIQMEAGNQALKAVFNSKLVGKGKYLTEHLQPHSTDD YRILVDMRWNKQYLDILANTCNFEDEERCMEFMEALYAVANRLIILMDREERAAICSSTG NTSPSNSALRLATAFSKGTVDIAQLPHPVLMHLRSFFDLWDAFVLQAVQTDQPNISDHLM FEILQLLQWRDRFWNVCNSLPADTRGVCVLSLHWQWVHKHLVLRLPQLLMGDGDYEGQQE LHTISSAIQNTLSSSVSVALALKSIQKTLGKPLPFKSESVAECSAQLRVFSKAFDVRDLR LNDRAPSRWKQEVARLRGVAMRTDCKEALLEGWGLVLQANLLLDPQSTGVLERLRTCVDQ QQGYMASFGLLDPVSEAENEQETGYGAGPDRGLLLRLARRAQLWPVLEELAILNQMKVTA DLLHQSVTRRGSKNEEEDLRRSLSNHLRFCMQSTPLNIRLLQPLWFLLSTERPVDELSLV WCELLSETLAALWSGSVTSDPDRWLKWSPLSPEEETKKSFRSLLGPSDTGPGMLSRAVWS RCVLGVLSSSETGGCWDPSGSSFLTSSRVTLGEWRERIGQLQDLNAVLWDNLAMSELADF RLTDRRLQGLVLCRQLHALSDLLSPGLQESYAESCDALIEGEDPVGAAQDIQVALREGLP ENLLPEGFLDTLVTCLTQFSHNRACDGVQLARSGVFWVNMGLLQIQVWVPQTIFDPAVKR AYKLKYAQDELALLQDEWNGRSLSSQLLTGVQLEESSTTDAFQHPRIRYLWIRMRQVKEQ ICELGRKQACRPAEPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQGSGPKSRPGIQ GLLKEEAVWQASQQRFSQRLADEYPLYPDVVVPLRSAILQLQHGMRLLASQVASTLVALP GLPRLVSTLLAFPAPPLSSDLERSQYLCSRTCMDTLRGLERVLPDTEVTCVVPEPVVLLL SALLCLQSHAISTGELGTEAQNLLRHVCQALVNEWDEQERRAREKEQKEASLYRSRSKLH GGGLSEEQQEERDFRRTFPTYHKDFADITTEPSLEQPIIIEDDEECDGETEPNDSAVFRV SGCQKTVVQVHQKLCLAFAQSPWYRPNPPGDRSKEHLSTLVSSYQIAAPLIARFYHLLDC EMDPQLTGCQLLLSSVLQNTVRGSGGPAGLILQSDGPYDFYREPNMCQARLCLPAIEQLA RAVCRRLDDWPDHPALVQITVVIERILAFSLSSPLAKFLNGLEILLSKSQDWENNASRAV SLRSELEPITQLIIQWRKLELNCWSSSLDNALRRHAENSSKHWFSIYQLIERYLQEKRTD DKPDLSRSVIPLVDVKDGGVKELPLPSVSSTLQGFVEGSTLGEFHTRLAMLLAFHCHVLL APKQEGHASLCSLLWNLHKYYTQFSDSIQARITQLRAPIEKELKDFVRISKWNDVSFWAI KQSVEKTHRTLFKFVRKFEEALSGPCAPWMVEQKSGGSTDSVDGQQEHTPLHQLHRALKS ALPGRRRDLQSDGPDEVPSSTEPSSLQARLPSLTRKMRKMCVQLVKKAPLPELSEDLDQF TVEIISNVQALQSLTVDRSLEQERQKAEAKQILLQKQRALADLFKMLAQIGLSYRKGLTW GRIADPEEPLLLQPVEMRTTLAALRTQEPTENLLFTEMIGTWDGCQKYFYRSWARRNAMQ AAMQAAVKELGLGNVERCRGFSSHLFKLLLRQRRRLAKITEHFADLRRLIDAVQDVRSQT ASGEDEQSGLPPQDSLCSWAAKARTLAQQCCVAVQQLSWVLQCCPEGCESREGGQGEATL SHPTPLPAHLQPQACLMRRGEASWAEAVKHVEALQSESTQLKERLNALGHESEQTAIQTR RHLEECSSCVHALGALADRMAVLESLFDLDGSVAPRSQPCLTRGLRGIRTEVGTHVKEFT AWRSQLRPLRASSKRSAAPFRAEFSEELERTINTVLCAVQGLVKRREQEVQKEDSRKESD SEVAEELLKPGHLSRLLEEDLSGDVSCLALAEVTGVTGRLLERLRSYRDTCPARHLGELK EACRNLVRLEPMLHVYSELVRWYVAVCMGAHRSTGKLLSVLAGVFTDLAQKGFCLPQELT GGGDGEGATEFHDYEGGGIGEGEGVKDVSDKIENEEQVEDTFQEGQEKSEEEPDKRDIKE EDNAVEMSEDFDGKMHDGEPRESGDEEDSDEEDEELDKKMGDLGDGPTDTLDERMWGDEE DDDDDDDGSDKEDESGPGMDQGASELVAKDDNTEAGESSKDKKNKDKDDAMDIEDEKEKI HEQVDEREFDENEADPYHGKQEQKAEAEAMDLPEELNLDQDEQAGQDEEGEGEDEAENPY DIADKPMEVDEGEEGEETMEDQKDSQGEEAGEEQNAEEETGGEQTDREKDSETDERGEDE GEGDEEEKEKGQEEGREEDKAVPADLGQKPKNEERDGVEEEEEEDAQLESAERKEHATDG QTGEENVQSDTAAELAGAASERDQAKEEHGTGSADASQAEGHDSTLVARMSSRTQRQKPT QSFKRKPGRADNERSLGDASERVHKRLRTVESAELREQEHAPDDGPRESDTYEHVRHGEE KYDTQTYDTASAEQQRPTSTKQDDDDDVAMDTEVEKEMQAADTLELKPEKPDSSKASKGM DSGDLDTWKPEEEEAAEKPETKTGHDEEQRRGRSKESTVHTVPELLTQVLKLQVKDPDLL RRDLELQLEAWHRQTPGSPEEESAAAAMWQQYQALTSPLSQQLCEQLRLILEPTQAAKLK GDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRDYQICLAVDDSSSMVDNHSKQLA FESVSVIVNALTLLEVGQVAVCSFGESVQLLHPFQQQFNDQSGARILRLCQFQQKKTRIA QFLETSANMFVAAKHQNPCSANTEMAQLLLIVSDGRGLFLEGKERVAAAVQAARSANVFV IFVVLDNPNSRDSILDIKVPIFKGPGELPEIRSYMDEFPFPFYVILRDVNALPETLSDAL RQWFELITATDR NT seq 16599 nt NT seq  +upstreamnt  +downstreamnt atggagactctggagctgagcctggcatccctggccacgatttccagacacgtcgaaaaa agtcacggcgagctcagcaagtatttaacgaagcagatatggagccagcaggacagacaa gccatcctgtgctgtttgactcagctcctgatagagaaggagtacacgctcctgatcgct cggcacctgcggccgctcgtgctcgacctgctagagaggaacgccgagcgaatcaagaag gacgttcgcctcaaccacgacctccacgagagactgtgtgtggcgctcagcaagctcctc agtgtcagccccgatgctcaggcgtttgcggcgaggtacttcaccagcgcgccgcccgtc tttcagagactcttcttcaccagcgaagaggccgcctctatccactacggccccaggcgc atgaagctgcgtgacctgatgggggccaccctccgcttcctgcagagcgactgcgagaag ttccgcgtgctgtgggactggagcgcctgcatctcgcagctgctcacgagtgacgtcatg gtccgaggttacacagcgcagtgccttgctttggtgtcccacatgaccgacaaccagaaa acaatcttcctgaggaaggttctgtccagtgacgagattctgcatctaaaaatgaagtcg ctagaggaaactcagcagctggaggttgagagagctctggttttagccaatcagggctct gtgatgtggcagttggaaaaaggaaataagctcaccaaggggcagatggggtcaggagac ctgtcgcagggcatcaccgctgtgtgcggtgtgatcttggccagactgacgcctcgacag gaagagcagacgtctttgaaaaccctggtgctggtggattcgacgtgtcgaaacctccgg cggctcgccatggccgtcgcgtcccagaggcccgttcttctggaaggacctatcggatgt gggaaaacggctctggtcgaatatctagcagccgctacgggccacgtcaaatcccccaac atcctcaaggttcagctgggagatcagacagacagcaaaatgttgcttgggatgtacaga tgcacagacatccctggcaagtttgtgtggcagcccggatccctgactcaggccgtatcc aagggttactggatcctcctggaggatatcgatcacgcaccgttggatgtgatatccgtg ctgctgccgctgatggagaacaagaagctgaccattccaggccgggaggactgcattcag gtcgctccaggcttccagttcttcgctacgagacggatcttctacagcggtggagtgtgg caccggccccagagcacccacgctgctctactagacaagtactggaacaagctgcagatt gggaatatgaccagagaggaactcaaacaggtcgtgctagataagttccctaacttggct gtggtggtggatcgattactggacatttattgtcagctgaccggcgacaaacaccacgtc gctgtcgccgctcctggcccacagaacccaagtgaggaccgacccaccatgctggaaggc cgaggactctctctgagggatttgctgaagtggtgtgagagaatatacgtgaacttcgac agctcgtcctcgaacacggcgcagaacgtcttcctggaggccctcgactgcttcaccgcc atgcagtccaaagcagagagccgcctgaagttggccgaggtcatcggcagcaagctgaac atctccaaagagaaggctcagcacttctgtcagatgtaccagcctgccatcagtatcacg gagctggaggtgacggtaggacgcgccatgctgctgcggaagcagagcgacgccgtgcgc ctcgacgtagataagcaaacgttcgcggccacacgtccctcctccgtgcttctggagcag ctggccgtgtgcgtcacgaaaggcgagcccgtgttgttggttggcgagacgggcacaggg aagacctccaccgtgcagtatttagctggattaacaggacacaagctgcgtgtgatcaac atgaaccagcagagcgacaccgctgatctcctgggagggtacaaacccgtggatcataag ctcatcctgttgcccctgcgcgaggcgtttgaggatctgttctctcagacgtactcccgc aagcagaacataaccttcctgggtcacgtgcagacctgcttccgagggaaacgctggcag gacctgctcaagctcatggaccacgtgtgcaagtcggccctcaccaaggagctgcaggac aagcctaatgctgcgttgctgcagcagcagtgggaggcactcgctctgagactcagccag acgcaggagcagatccgagctcgggaatcggcactggtgtttgccttcgtcgagggtacc ctggcgcaggcagtcaagaagggagagtggatcctgctcgatgagatcaacctggccgca gccgaaaccctagagtgtctgagcgggctgctagagggcagcgccgggtctctggtgctg ctcgaccgaggagatacagaacccctggtgcgccactccgacttccgcctgttcgcctgc atgaacccggccaccgacgtaggcaagaggaacctgcccctgggaatccgcaacaggttt accgagctgtacgtagaagagctggagagcgagggcgatctacgcgtcctggtctcggat tacctcaaaggccttaacttgaacagaagtaccatccatggaatcatcagtttttatttg gccattcgcaaggaggcgagctcgcgcttggtggacggcactggccacaagcctcactac agtttacgcacactgtgccgtgctctcaagtacgtcgccactaacccctgctacaacgtc caacggtctctcttcgagggtttttgcttaagctttctaacacagctggaccgtagttcc catcccgtcgtggagaaattagtgcaccagtacattctgggaggaaacatcaagtgtctt aaacagccaatcccggagccccgctcccgtggctgtctgcagatcgagggctactggttg tgtcagggtgacatggacccagcactggacccgagctacatcctcactccttctgtgcgc ctcaacctccgagacctggcccgcgttgtggctgccggcatccacccagtgctgatccag ggtgagacgtcggtagggaaaaccagcctggtccggtggctagcggctgccacggggaac cagtgcgtgaggatcaacaaccacgagcacacagacatccaggagtacatcggctgctac tcatccgacgagcacgggaagctcgtcttcaaagaaggcgtcctgatcgatgccatgcgg aagggctattggatcatcctggacgaactgaacctcgcccccaccgacgtcctcgaagcc ctgaacaggctgctagatgacaacagggaactcttcgtcgccgagacacaggaagtagtg aaggcacatccgagattcatgctctttgctacccagaatcccccaggtctctacggtggc agaaaggtcttgtcgagggcgttcaggaatcgctttgtggagctgcattttgacgagtta cccagcgaagagctggagaccatccttcaccagcgctgcagccttcctccatcttactgc accaaactggtcaaagtcatgcagaaccttcagtctttgcggcgtggatccagcgtgttc gccgggaagcacggttacatcaccctcagagatttgttccgatgggccgagcgctataga ctggaagagcagaccgactcgtcacgtgactggctgcaacatctagccgacgacgggtac atgctgctggcgggccgggtccgtaagccagaggaggctttaaccatccagaacgttctg gaaaagcactttaagaggacggtaaacccagatgcactgttctctgaggatcaggtcaac acccagttcagtccgtttgtggccagccttgctggcatgcctgaggagtttggtcatgtg gtttggacccaaggcatgaggaggcttgccgtgctggtgggtcgtgcgctccgttttgga gagtccgtcctgctggtgggcgacaccgggtgtggtaagaccacaatatgccagctgttt gctgctctggctggactgaagtttttcgctgtgaattgccacctgcacatggagacgtcc gacttcttgggcggtttacggccggtccggcacatcggaacgggccaggcggatgctgaa gatggccgtttgtttgaatggcgcgatggacctctggtgcttgctatgaaacaggaagga gtgtttttgatggatgagatctcactggctgacgactccgtgttggagagactcaatagc gtattggagacggagaaatctctggtcctggcagagaaaggcagcagtgatgacgacgac gtcgagctcatcatcgccgggaagaaatttcgactggttgcgactatgaaccccggtgga gatttcggcaagaaagagctttccccagcattgaggaacaggttcactgagatctggtgt cctcagtctaacagccgcggtgatctgatgaagatcgtccagcacaacttgcgagcaggg ctttctttagaccagcacgaccaccaaggcaaggacgtcgccgaggtcatgttggacttc atagactggctgaccaatcaggagtttgggaggcgatgcatcctaagcgtaagggacatc ctgtcttgggtggacttcctgaatgccgtgtgcgagaaggacgaggatcgagatgagagc agcttcatgggtctggaggagatagaggagccggagtgggaccagaggctggacacggtc actgccttcatccacgccgcctgcctcgtttacatcgacggcatcggatcagggacaaca gtctcggcagcagagaacgtcgcggcggcgaggaaggcgtgtctggcttttctggagacg aagctacgcaggatcactaagctagacgagaagatgcaggaggctctgagggtttacgac accagcctggtcagagagccacgctggggggacgacttcttcggcatcgagcccttctac gtcgtggccgatcccgagagcgaaagccgcggtctgttagactacgccctcggtgcaggc acgacagcggtgaataccatgaggatcttgcgtgcgctaaagctccagagacccatcctg ctggagggttcacccggagtgggcaagaccagtctcgtggccgcgcttgccaaggcctct gggaaccagctcatcagaatcaacctctctgagcagacagatgttacagacttgtttgga actgaccttccagtggagggcggtaaaggaggagagtttgcttggcgtgacggtcctctc cttgctgctctaaaggccggacattggatcgtactagatgagctgaacctggcctctcag tcggtgttggagggtctgaacgcctgcttcgatcaccgagcagaaatctacatcccggaa ctgagcatacgtttccaggtccggcatgagaaaaccaagatctttggctgccagaacccc ttcacacaaggaggcggtcgcaaaggcctgcccaagtccttcctcaacaggtttactcag gtgtacgtggaccagctcagcagtgaagatatgcagttcattggtaactccatctttcca aacatcagtgagcagatcatctctaaaatggttcagttcagcaacaagcttgtgaccgag gtggcagtagagagaaaatggggtcagaaaggaggaccgtgggagttcaacctgcgagac ctgttccgttggtgtcagctgatgcaagccgaccaatcaccagccttctataacccgggc cagcacgttggactggtgtacgcggaccggatgcgaacggaagcagataaggctcaggtg ctgtctgtcttcaggaaggtgttcgctgaagatttcgagcctcacttaggctccaggcag ttccatatcactcctctaaatctgcaggtgggctcgtcagtccttcagcgcagcggcgga gcccctgtggtcttggatcctcctctgtcgatcactcatcaagctctgcggccgctggag tccttaatgaaatgcgtgaagatgggctggatggctatactggtgggccccagcgccagt gggaagagcagtctggtgcacctgcttgccttgctgaccggacacaggctcagggtgatg gctatgaacagcgccatggacactaccgaactgctgggcgggtttgaacaggtggatatc atccgaccatggcagcaggtcttggagagcatggactacgtggtggccatggtgacacgg cgcgggctgatgtctctggacggaggggtccaggacacagagttccttctgagcacctgg agcacgttccgccgctggctgaaggacgagggactcgacacggctgacggcacggtgacg ttcgaggccctgaacaagctagaggtcatcatcgtgctgctacacaaactcaacaccaag ctcaaggtcttcacagacatgtcgaagctgcagatggacttcacccttctgaaggagcgc ttggcgcagatggaggacggttggagtcacggcggtttcgaatggctggatggcacgttg gtccaggcactgcaggccggagactggctactcatggacaacgtcaacttctgcagccca tctgtgctggatcgtctgaacgctcttctggagcctggagggtctttgaccatcaatgag cgcggggtcatagacggcacaacgccgagcatcacaccgcaccctaacttcaggctattc ctcaccatggaccccacgcatggggagatctcccgtgccatgaggaaccgcggcgtggag atctacgtcccgggagagaacgagggagcgtgttgggactcgctggacctgaagacgatc ttgcacactctgggcgtgaccggagattgcgtgtgcgacctgctgatgaccgttcattcc gagatcaagtcggccatctgggattcgccggcgtcctccgtgtcatctctgctgcatgcg gcggcgctgttgtccggtcagctgcagagaggtgtagacctgcccagcgccctcctgcag gcatgtggggaagcgtacgccctctgtcagcgcacctctgccaaccaaaagctcgctcag gagctgatagagaggcagttggcggtgttagactcggaagaatggggtagtggactggtg tgtgcaggcgtgtggccggatcgagtgccttctgcgctgcagtccacagaagattcgtgc ttttcaagcgtccagagggacggccaggtcctcctctactgtctgaacacgctcagcctg cacagcaagaggagtcgcccgctgatcctgactgacctgcagagggcgatgcagagcggt gcagctctggaaaccctgcagtttcctccagaaggcggcagtgcaggtgacaggatcagg gacgcccagcagctcctccccacggcggtgcggatcctgaccgagggagcctcccacagc gactgggtcctgcgtacaagctggctctcgcacctcgccaaaagctacaaacacgtacca gaagccgcgctgatacagatggaggcgggaaatcaggctctcaaagcggtcttcaacagc aagctcgtcggcaagggcaaatacctgaccgagcaccttcaaccccacagcacggatgac tacaggatcctggtagacatgcgctggaacaaacagtacctggacatcctggcgaacacc tgtaacttcgaggacgaggagcggtgtatggagtttatggaagctctgtacgccgtcgcc aacaggctcataatactgatggaccgagaggagagagcagctatatgcagcagcacagga aatacatcacccagtaacagtgcgctaagattggccactgccttttctaaagggacggta gatattgcgcagctgccccatccggtcctgatgcacctgcgctctttcttcgacctgtgg gacgccttcgttctgcaggccgtgcagacggaccagccgaacatctcggaccacctcatg ttcgagatcttgcagctgctccagtggcgagaccgtttctggaatgtgtgtaactccttg ccggcggacacacgcggagtgtgtgtgctctccctgcactggcagtgggtccacaaacac ctggtactacggctgccccagctcctgatgggcgacggagactacgaagggcagcaagag ctacacaccatctcctcagcgatccagaacacactctccagctctgtgtctgtggcactg gcactaaagagcatccagaaaaccctgggaaagcctcttccgtttaagtcagagagcgtg gccgaatgctccgcccagctccgcgtcttcagcaaggctttcgatgtcagggacttgcgc ctgaacgacagagcgccgtcgcggtggaaacaggaagtggcccggctgcggggcgttgcc atgagaacagactgcaaggaagccctgcttgaaggctggggtctggtcctgcaggctaac cttcttcttgatccgcagagtaccggtgtcctggagagattacgtacctgtgtggatcag cagcagggatacatggcgtcctttggcctgctggatccggtctccgaagccgagaacgag caggagacgggatacggcgcaggaccggaccgtgggctgttactgcggctggctcgcagg gctcagctctggcctgtgctggaggaactcgccatcctcaaccagatgaaagtgactgcg gatctgctacaccagtctgtcacacgcagagggagtaaaaatgaggaggaagacctccga agatccctgtccaaccacctgcgcttctgcatgcagtccacccccttgaacatccgtctg ctccagccactgtggttcctcctcagcacagagcggcctgtagacgagctgtcgttggtg tggtgtgagctgctttccgagacgctggcagcgctctggagtggcagcgtgacctccgat cctgatcgctggctcaaatggagccctctgagtcctgaggaagagacgaagaagagcttc cgatcgctgctggggccctctgatacgggtcccggcatgttgagccgagccgtgtggtcc cggtgcgtgctgggggttttgagcagcagtgaaacgggcgggtgctgggacccatcgggc tcgtccttcctgacctcgtcgcgagtaacgctgggcgagtggagagagcggatcgggcaa ctccaggacctcaacgcagtgctgtgggacaacctggccatgtccgaactcgccgacttt agattaacagaccgcaggttgcagggcctggtcctgtgccggcagctgcacgcgctctct gacctgctgtctccagggttacaggagagctacgcagaatcctgcgacgctctcatcgaa ggcgaggaccccgtcggtgcggcgcaggacattcaggtcgccctgcgagaaggcctgccc gaaaaccttctcccagaaggcttcctggacacattggtgacttgcttgacccagttttcg cacaaccgggcgtgcgacggtgtccagctggcccgctccggggtgttctgggtgaacatg ggcctgctgcagatccaagtttgggttccacagacgatatttgacccagcagtaaagcgg gcctacaaactcaaatacgcacaagacgagcttgccttacttcaagatgaatggaatggg cggagtctgtcatctcagctgctcacaggggtgcagcttgaagagagcagcaccacggat gccttccaacatccccgaatcaggtacctgtggatccgcatgcgacaggttaaagaacag atctgcgagctcgggcgtaaacaggcatgccggcccgctgagccccagtacggacgcctg taccaggagctccagcactacctgtgcagcatcgggcagccagcagcagtgggcgacctg ctgtcacacctgctcaaggccctgcagggctccggccccaaatcccgcccaggcatccaa ggcctgttaaaggaggaggccgtgtggcaggcatcacagcagcgtttctcccagcgcctg gccgacgagtacccgctgtacccggacgtcgtggtgcccttgcgctccgctatcctgcag ctgcagcacggtatgcgtctgctggcctcacaagtggcgtctacgttggtcgcgctccca ggtctcccgcgcctcgtctccacgctgctggcttttcctgcaccgccgctgagctctgat ctagagcgctcccagtacctgtgctcccggacatgcatggacactcttcgaggactggag agggtccttcctgacaccgaggtgacctgcgtggtcccggagcctgtcgtgttactgctc agcgccctgctgtgtctgcagagccacgcaataagtacaggagagcttgggacagaggca cagaatctgctcagacacgtgtgtcaggcactggtgaacgagtgggatgagcaggagagg agagcgagggagaaagagcagaaggaggccagtttgtatcgcagtcgctctaaactacac ggaggaggcctcagcgaggagcagcaggaggagcgtgatttcaggcgcaccttccccacg taccacaaagattttgctgacatcacaacagaacccagtctggagcagccaatcattatc gaggatgatgaagaatgtgacggggagacggagcctaacgacagcgccgtcttcagagtg tccggctgccagaagaccgtcgttcaggtgcatcagaaactgtgcctggccttcgcacaa tcgccgtggtaccgtccgaatccaccgggcgatcggagcaaagaacacctcagcacgttg gtctcgtcttatcagatcgccgcacctttaatagctcgcttctatcatcttctggactgt gaaatggatcctcagctgacgggctgtcagcttctgctcagttccgtgctacagaacacg gtccggggctccggaggtccggccgggttaatcctccagagcgacggaccgtacgacttc taccgcgagccaaacatgtgccaggctcggctgtgccttcctgccatcgagcagctagcc cgcgcagtctgccggcgtctagacgactggcctgatcacccggcgctggtgcagatcact gtggtgatcgagaggatactagcattcagtctgtccagcccactggccaagttccttaac gggctggagatcctgctcagcaaatcacaggactgggagaataacgccagtcgcgctgtg tctttgaggagcgagttggagcccatcacacagctcatcatccagtggaggaaactggag cttaactgttggtctagcagtctggataacgctctgaggcggcacgcggagaactcgagc aagcactggttctccatctaccagctgatcgagagatatctacaggagaaacggaccgac gacaaacccgatttgtcccgttctgtcatcccgctcgtagacgtgaaggacggaggtgtg aaggagttgcccctgccctcggtttcatccacactgcagggcttcgtggagggatccaca ctgggcgagtttcacacgcgcttggccatgctgctcgccttccactgccacgtcctattg gctcccaaacaagaaggacacgcctcgctgtgtagtttgctgtggaacctccacaagtac tacacacagttctctgacagcatccaggccagaatcacgcagctgagagcgcccatcgaa aaagaactcaaggactttgtgaggatctccaagtggaatgatgtgagtttttgggctatc aaacagtctgtggagaaaacacacaggaccctgttcaagttcgtgaggaagttcgaggag gcgttgtccgggccgtgcgctccctggatggtggagcagaaaagcggcggcagcacggac agcgtggacgggcagcaagagcacacgccgctgcaccagctccaccgcgcactcaagagc gccctccctggacgacgcagagacctacagagcgacggtccagacgaggtcccgtccagc acggagccctcgtcgctgcaggctcgtctcccctcgctcacaaggaagatgcggaagatg tgcgtgcagctggtgaagaaggcgccgctgcccgaactgtcagaagacctcgaccagttc acagtggagataattagcaacgttcaggcactgcagagcctgacggtggaccgctctcta gagcaggagaggcaaaaagctgaagcgaaacagatcctgctgcagaaacagcgagctctg gctgacctctttaagatgctggcgcagatcggtctctcgtatcgtaaaggcctgacgtgg ggtcgtatagcagatccggaagaaccgctcttactgcagcctgtagagatgagaacaaca ctggctgcactgagaacacaggaacccacagaaaacctgctgtttactgagatgattggc acatgggacggctgtcagaaatatttctaccgctcctgggccagacgtaacgccatgcaa gctgcaatgcaggcagctgtaaaggagctcggtttgggtaacgtggagcgatgccggggc ttctcctctcacctgttcaaactgctgctcaggcaaaggcgccgcctggccaaaataacg gaacacttcgcggatctcagaagattgatcgacgccgtgcaggacgtccggtctcagacg gcctcgggagaggacgagcagagcgggcttccccctcaggactctctctgcagctgggcg gcgaaggcgcggacgctggcgcagcagtgctgcgtggccgtgcagcagctctcctgggtg ctgcagtgctgtcccgaggggtgcgagtccagagagggcgggcagggcgaggccacgctg agccaccctacacctctgccagctcacctccaacctcaggcgtgcctaatgaggcggggc gaggcgagctgggcggaggccgtgaagcacgtagaggctttgcagagcgagagcacgcag ctgaaagagaggcttaacgccctggggcatgaatctgaacaaacagcgatccaaaccagg aggcacttggaggagtgcagctcatgcgtgcacgctttaggagcactggcagaccggatg gcggtcctggagagcctcttcgacctcgatggcagcgtcgcacctcgttcgcagccgtgt ctcacacgaggcctgcgcggcatccggacggaggtgggaacccacgtcaaggagttcacc gcctggagatcacaactgcgaccactccgagcatcatccaaacgttccgccgcgccgttc cgggccgagttctccgaggagctggagagaaccataaacacggttctgtgtgccgtgcaa ggactggtgaagaggagagaacaggaagtgcagaaagaggacagcaggaaagagagcgat tccgaggtggccgaggagcttttgaagcctggacacctgagccggttactggaggaggac cttagtggagacgtgtcgtgtctcgccctggctgaggtcactggggtcacggggaggttg ctggagaggctgcgatcctacagagacacgtgtccggcacggcacttaggggagctgaag gaggcctgcaggaatctggttcgcctggagcccatgctgcatgtgtactcggagctggta cgctggtacgtggccgtgtgtatgggcgctcaccgcagcacgggcaaactgctgtccgtc ctcgccggcgtcttcaccgacctcgctcagaagggattctgtttgccccaggagttaacg ggcggaggtgacggagaaggagctacggagttccacgactacgagggcggcgggatcgga gagggcgagggcgtcaaagatgtcagcgacaagatcgaaaacgaagagcaggtcgaggac acgtttcaggaagggcaggaaaagagcgaagaggagccagacaagcgggatattaaagaa gaagacaacgccgtcgagatgtccgaggacttcgacgggaaaatgcacgacggggagcca cgagaatcaggtgacgaggaggactctgatgaagaagatgaggagctggataagaaaatg ggagacttgggagatgggccaactgacaccctggatgaaaggatgtggggtgacgaggaa gacgacgacgacgatgatgacggcagtgacaaggaggacgagtccgggccgggaatggac cagggagcgtccgagctggtcgccaaagatgacaacacggaagccggggagtcgagtaaa gacaagaaaaacaaggacaaagacgatgcgatggacattgaagatgagaaggagaaaatc catgagcaggtagatgagcgcgagttcgacgagaacgaggcggacccctaccacggtaag caggagcagaaagccgaggcagaggccatggaccttccggaagagctcaacctggatcag gatgaacaggcaggacaggatgaggagggagaaggagaagacgaggccgagaacccgtac gacatagcggacaaacccatggaggtggacgagggagaggaaggcgaggagacgatggaa gaccagaaggactctcaaggtgaagaagcaggagaggaacagaatgcggaggaagagact ggaggggaacaaaccgaccgagagaaagactctgagacagatgagagaggagaagatgaa ggagaaggggatgaggaagagaaggagaagggacaggaagaaggtagagaggaggacaag gccgtccctgctgatctgggccagaaaccaaagaacgaagagcgggacggggtggaggag gaggaggaggaggatgcccagctggagtctgccgagagaaaggagcacgcgacggacggg cagaccggcgaggagaacgttcagagcgacacagcggccgagctggcaggagccgcgtcc gaaagagaccaggccaaagaggaacacggcaccgggtcggccgacgccagtcaggccgag gggcacgactccacgctggtggccaggatgagctctcggacgcagagacagaaaccgaca cagagttttaagcggaagccgggccgggcggataacgagcgttctctgggcgacgccagc gagcgtgtgcacaagcgtttgcgtacggtggagagcgcagagctgagagagcaggaacac gctcccgacgacggcccgcgggagtcggacacgtacgagcacgtcagacacggggaggag aagtacgacacgcagacatacgacacagcgagtgcagagcagcagagaccgacttccacg aagcaagacgacgacgacgacgttgctatggatacagaggtggagaaagagatgcaggca gcggacactctagagctgaagccggagaagccggacagctccaaagcctccaaaggtatg gacagcggagatctggacacctggaagcctgaagaggaagaagcagcggagaaaccggag acgaagacgggtcacgatgaagagcagaggagggggaggagcaaagagtccaccgtacac actgtgccggagttactgacgcaagtgctcaagctccaggttaaagatccagacctacta agaagagatttagagctgcagttggaagcgtggcacaggcagactccgggatctccggaa gaggagagcgcagcggcggcgatgtggcagcagtatcaagcgctcacctcgcctctgtcg cagcagctgtgcgagcagcttcgcctcatcctggagcccacgcaggccgccaagctcaaa ggagattaccgcacgggaaagcggctgaacatgcgcaaggtcatcccctacatcgccagc cagttccggaaagacaagatctggttgaggaggacgaagcccagcaagagagactatcag atctgcttggctgtggacgactcgtccagcatggtggacaatcactccaaacagttggcg ttcgagtcggtctccgtgattgtgaacgccctcaccctgctggaggtgggacaagtggca gtgtgcagcttcggtgagagcgtccagctgctccacccattccagcagcagtttaacgac caatcaggagctcgaatcctgcggctctgccagttccagcaaaagaagacgagaatagct caatttttggagacttcagccaacatgtttgtagcggccaaacatcaaaatccctgctct gcaaatacagagatggcgcagttgttgctgatcgtctccgacggcaggggcttgttcctg gaggggaaggagagagtagcggcggcggttcaggccgctcgcagcgccaacgtcttcgtc atatttgtagtgctggataaccccaactccagagactccatattggatatcaaagtgccc atcttcaagggaccgggcgaactgcccgagatccgctcctacatggacgagttcccgttt ccgttctacgtgatcctgcgcgacgtgaacgccctgcctgagacgctgagcgacgctctg aggcagtggttcgagctcatcactgccaccgaccggtaa

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