Ixodes scapularis (black-legged tick): 8026823 Help Entry 8026823           CDS       T01131                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism isc  Ixodes scapularis (black-legged tick) Brite KEGG Orthology (KO) [BR:isc00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:isc04040]     8026823    04990 Domain-containing proteins not elsewhere classified [BR:isc04990]     8026823 Ion channels [BR:isc04040]  Voltage-gated cation channels   Ryanodine receptor    8026823 Domain-containing proteins not elsewhere classified [BR:isc04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    8026823 SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_6 GET2 Motif Other DBs NCBI-GeneID:  8026823 NCBI-ProteinID:  XP_040073761 LinkDB All DBs Position Unknown AA seq 5156 aa AA seqDB search MGDAEGSSEQDDISFLRTDDMVCLQCIATGTRVCLAAEGFGNRHCYLENIADKNFPPEML SCVLVLEQALSVRALQEMVTAANSDTGKGTQSGHRTLLYGHAVLLRHQNSNMYLACLSSS SYNDKLAFDVGLQDHSQGEACWWTIHPASKQRSEGEKVRVGDDLILVSVATERYLHTAKE GDNAIVNASFHLTHWSVAPFGTGASRTKNVGYVFGGEVLRFFHGGDECLTIPPTWGQDPS QNIIVYEGGAVLNQARSLWRLELVRTKWAGGFVNWGYPLRIHHITTGQYLAFGENREVCL VPRQKATVAATAFCLRQTKDDKKVVLDEKEEEVLGSPLVKYGDTTVFLQHLETGLWLSYK TYETKKRGVGKVEEKQAIMSEEGKMDDGLEFSRAQVEESRTARVIRKCGSLFNKFIVNLD AMQNEGATEESAISTIDQDEMIMCFEDLINYFVQPEDDIEHEEKQNKLKALRNRQDLFQE EGILNLILETIDKINTITTSGYLMTAGGEDAGQNWDAISGFLYQLLAAIIKGNHTNCAQF AQPHRLDWLFSRLSSQQASEGTGMLDVLHCVLIDSPEALNIMKEDHIKVIISLLEKHGRD PKVLDVLCSLCVTGKGVAVRSSQNNICDNLLPGRNLLLQTRLVDHVASMQPNIFVGRVEG AALFRRWYYEAMVDHCEQRSHLEPHLRIGWANTAGYVPYPGGGSKWGGNGLGDDLYSFGF DGACLWTGGRSNAVRNAPAPFIRKGDVVGCIIDLNVPVISFTVNGIKVKGCFRNFNTDGM FYPAISFSAKLSCRFLLGGDQGKLRYGPPDGHSALVEALLPQQVLTVEPCFQFGDVPKGV LFGPAAISDDAVFVPAPVDTSAIALPNYIESVRDKLAENIHEVWSMKKIDAGWRYAEVRD DNRNVHPCLTSFEHLPPAEKKYDTTLALQTLKTILALGYHITVDKPPARIKTIKLPNDPY LQSNGYKPAPLDVGAISLTPKMEELVDLLSENTHNVWAQERIQHGWTYGLVENQPTRRSP HLVPYKTVDDIIKKANRDTASELVRTLLAYGYVLEPPTADSLEGAQSKVSSVKYDQRTYR AERTYAVTDGKWYFEFEVLTLGVMKVGWAGPNFLPSCELGGDDNSWAFDGFKAAKNHAGG SEVYGKQWQIGDVIGCMLDLHDRTISFSLNGELLLDSLGGETAFSDIPCGEGASYVPACT FGIGQKARLVFGHDVNLLRYFTTCGLQEGYQPFCVNMNRNMTFWYNKDEAVFVNVDDAFH PNVEVSRIPAGGECPPALKIIHKLFESVEKVNYEFLRLSLPVTCHDTLIEEIEKEQRWEE IRRRQRRAQAERKSIRHPANLEQHMLRSGFSMSDVKDLQRGYSEDAAEGDEMLHVEHRPP TPLQRRRSVHAGTLTKTQSFDAATTLQVPDGSGSRLRAASSEEALTRIGQPHKGQRSKAT TPEPEGKAKRRGKSPFRFFRSKKDEKEEKEPAPAQPAPAAPKAPTPATLAPPMLTVRAPS VQRLTPAGSQLLCPPVPDRPSGLGGGGIPRTGSSRRPSLAPAPPPADDTGDRLDPSVLDL VDEYFYGLRVFPGQDPSHVYCGWVTTTYKYHDRSFSNAKVRKVAYHGLSEDGLVHQVLER QNCYMVCAGQLATEISHGEAGSRSANQGMYVGCHIDLATGMLTFSADGHITRHRFKMEPG TKLYPAAFFEATSKEVLQFELGHTPTTLPLSAALLHNTSRHLTPQLPPRLKVQCVQPYVW ARVPNVSLRPHALRLSEVRGWSMLCEDPVSMLALHIPEEDRCIDILELIEHERLLNFHAH TLSLYGALCFQGNHRAAHMICSHVDEKQLMYAIQAEYLSGPLRTGFTDLLISLHLEFHAY ARSLTQNEFIVPLGPDIRELYQDPLKAHSFTTLECISIRPEMSFSETREQVDSIADLSTP YFPVDALKQFVIEALADAVKKDSRPNRDPIGGSNENLFVPLLKLADKLLLVGLLDDEDLQ WLLYLLDPETFDPNYRNAGNGGALGLIDMQVAEGVKLQICYILHHLCDLQMRHRVEAIVS FSDDYVGNLQTDQLRRYIEIKQSDLPSSVAAKKTREFRCSPKEQMRAILGFKHLEEENWD QCPCGEGLREVLSSMHADQLSRLKVATAAEEEAPEKEADGDRSLRQRLMHLVSLVRASEE ESGGGEERVTLPEEIFTKKVVHIVVKWAEQSEFENREVIRQMFRLLLRIYSSVSELMNAL ENTYVISHMSKSDIISVLSHLGKVRALLPVQMSSQEEEVMRKSLWALVNNRIFFQHPDLI RILRVNENVMDVMINTLGKRAQTQSSGQAPPAAAPAPASTPGQAAEAPHANKDTSHEMVV SCCRFLCYFCRTSRQNQKAMFDHLDFLLENSNILLSRPSLRGSTPLDVAYSSLMENSELA LALREHYLEKIAAYMSRCGLQSNLELIDRGYPDVGWDPVEGERYLDFLRFCVWVNGESVE ENANLVIRLLIRRPECLGPALRGEGPGLLDAIREAVRMSEHIVAERQQQAQAQGAAADEE ESEDDIDMGAAILNFYCTLVDLLGRCAPEAATIAQGKNECVRARAILRSLVPLDDLLGAL SLRFTLQTPRKGESGKTKSDLPPGLQPNHKQSIVMFLERVYGLENQDIFFRLLEDGFLPD LRAATMLDRTDNTESDMALALNRYIGNSVLPMLIQYYSYFSNAENYASLLDATLHTVYRL SKVKILTKGQREKVSDFLVALTREMQPSMLLRLLRKLTVDVSVITEYTTVALRLLTLHYE RCKSYYSASGGQGAYGTASEEERRLTMLLFTNIFDSLSKMEYDPELFSKALPCLTAISCA LPPDYSLTEGQDDDWCKQGTHTSGPYVPEPVNTSGIQLSQDLHNIVQRFSEHFHDAWATR KMERGWQYGERWNDDVKTHPRLKPYNLLTDYEKERYRDPIRELLKALLAFGWKLELTDSS QRSAAPIAAQAPSPMAYMPTPVDMSTLTLNKDMMTMSERLGENTHDIWAKKMKEELEAVG GGIHPQLVPYDLLTDREKYKNRDRAQEFLKFLQYEGYRLSSKMTRRRERGGAPSEEPMSP AVGAAQGLERRFASLLLEKLLQYLDVAAINLKVLRPSIPFSRRNSFKASSRDVKFFSKVV LPLMEKCFVAHRAFFLMSPTATSTVGTATIREKEMVASLFCKLGGLLRAKFSVFGNQSKI TVSCLQVLIRATDARTIVKNCPDFVKTSMMTYFNNAADDLAQTLLNLEQGRYSHLRGTTM KTSSSLNYVQFVLLPVLTAVFDHLAANEFGSDLLLDDIQVACYKILNSLYTLGTRTDLHG GRSFVKAELERHRPAYGNCLGAFAATFPVAFLEPSHNKHNPHCIHGKAQEHSLEAQAVMA TLESSMPTLDDLMGQVEKFVTANGKYSEQPYIIEVMLPMLCSYLPFWWSQGPDNVNPTTG NHVTMVTSDHLTNLLRNILNLLRKTVSVEGSPWMITFAGHAGQIVINSSEELLRDPILPL MEKIQHSADLVFHKEECMRSYLKSSTDDTSQAEGQLQEEFTLLVRDIYAFFPLLIKYVDL QRNHWLKNNVKEAELVYTRVAHVFNIWNKSQYFRREEANFISQHEIDNMALIMPSSGRGR ASVQTTDASQSQKKEKKKKRDGKRDKDKELAASLVVACLKRLLPVGLNLFAGREQELVQH AKEKFLNKDQDVDIFDYVKLQLTLPDKIDPSDAMSWQHYLYSKLGSQRSSGSQIVPAQVS HDQLVERIMDMAKVLYGLHMIDHPQGSMKGVYRSVVSTQRKRAVIACFRMISLHSLPRHR AINIFLKIYKELWLEDENVGQEELIDHLTTTFEDSEKETSTEEAEEKPDPLVQLVVAFSR TATTEHSGVIPEDPLYMQYAFIFSQSCGGAEEEEEEEEGDDDAGPSIHEQELEKQRLLFH QARLASRGVAEMALLYISACKGAQGPMVMETLKLGISLLKGGNQEVQVRMLQHLKEKRDV GFFTSIAGLMNSCSVLDLDAFERTQKAEGLGVGSEGTAGEKNMHDADFTCALFRFLQLLC EGHNLEFQNYLRTQAGNTTTVNVVISTVDYLLRLQESVMDFYWHYSSKEVIDQPGKDNFC RAITVAKQVFNTLTEFIQGPCSLNQQALAHSRLWDAVGGFLFLFAHMQDKLSKNSSQLDL LKELLELQQEMIIMMLSMLEGNVMNGTIGKQMVDTLVESASNVEMILRFFDMFLKLKELT SSSSFQEIDSNNSGWITPKDFQKAMEQQKIYNPDEIAFLMSCCEPNIDDLIDYREFTERF HNPAKDIGFNVAVLLTNLSEHMPNDPRLHRFLETASSVLNYFEPFLGRIEIMGGSKRIER VYFEIKESTIDQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMQHASSIS NEDTEEPPAKAEPYTFLGAEESRPPGPMEPLKQGFWLLRDAIGALLSVLRPSYLKRQFQA LRRKSLGELLMGLFRFSFFGFFYVIWLGLHCSKSLVGIIIRLMGGQPLAGDTLPEEDISK GALLLPQRPLAALEGIPSQMGSLPADAETPTHARVSGHEANKLDEDGDLKHNAPKAPMSP QASTDLADQDQVGDEEHAKGAPGVKSPDGELPDGLTADGQISHLDGDIKLKDMEQLQGSM DAKRALPGPEAMPPSPLLMPPMASPEAAKPSETPPVAAIDLSEYSQKIVSFLARNFYNMK YIALVLAFFINFILLFYKVTTGEEDADAGSGSDDEAEPASTVGNGLADLLSNATEAVASG SDSEDEDLEEWVIIEEKFFYLEPVIRFMALFHSLVSFCMLIAYYHLKVPLAIFKREKEVA RAMEFDGLYISEEPAEDDIRTRWDKLVISTKSFPVNYWDKFVKKRVRQKYSETYDPEALS NVLGMDKSGSFSQEQEESGGLIPFITNADWKYQIWKSGVTITDNSFLYNLWYFLFSVMGN LNYFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFSFFRKFY IQEEDDQVDPKCHSMLSCFVFHLYKGVRAGGGIGDEIGPPDGDDYEVYRIIFDITFFFFV IVILLAIIQGLIIDAFGELRDQLQSVVDDMESNCFICGIGKDYFDRVPHGFDTHVQKEHN LANYMFFLMHLINKPDTEYTGQETFVWELYQKRCWDFFPVGDCFRKQYEDELMGAG NT seq 15471 nt NT seq  +upstreamnt  +downstreamnt atgggggacgccgaaggctcgtccgagcaggatgacatctccttcctgcgaacggacgac atggtgtgcctgcagtgcatcgccaccggcacgcgggtctgcctggcggcggagggcttc ggcaatcgccactgctacctggagaacatcgccgacaagaacttccctccggagatgctg tcctgcgtgctggtcctcgagcaggcgctgtccgttcgcgccctccaggagatggtcaca gccgcaaactccgacacgggcaaaggcacccaatccggccaccgaaccctcctctatgga cacgcagtgctgctcaggcatcaaaacagcaacatgtacctggcctgtctttcaagcagc tcgtacaacgacaagctcgcctttgacgtggggctccaagatcattcgcagggggaagcg tgctggtggaccatccacccggcgtccaagcagagatccgagggcgaaaaggtgcgggtc ggagatgacctcatcctcgtcagcgtggccacggagcgctacctgcatacagctaaagaa ggcgacaacgctatcgtcaacgccagtttccacctaacccactggtctgttgcgccgttc gggaccggcgctagcaggacgaagaacgtcgggtatgtgttcggaggagaggtgcttcgg tttttccacggaggcgacgagtgcctcaccattccaccaacatggggacaggacccgagc cagaacatcatcgtgtacgagggcggcgccgtgctcaatcaagcccgctcgctctggagg ctggagctcgtgcgcaccaagtgggcaggcggcttcgtgaactggggctacccactgcgg attcaccacatcaccacggggcagtatttggctttcggtgaaaaccgggaggtgtgcctg gtgccgcgccagaaggccaccgtggccgccacagcgttctgcctccgacagaccaaggac gacaagaaagtggtgctggacgagaaggaggaagaggtgctaggctcgcccctcgtcaag tacggcgacacaaccgtcttcctgcagcacctagagactgggctgtggctctcatacaag acctacgagacgaaaaagaggggcgtgggcaaagtggaagaaaaacaggcaatcatgtcc gaggagggcaagatggacgacggcctggagttcagccgcgcccaagtcgaagagtcgcgc accgccagggttatccgcaaatgtggctccctcttcaacaaattcatcgtgaatttggac gctatgcagaatgaaggcgccacagaagagtctgcaatcagcacgatagaccaagacgaa atgatcatgtgcttcgaagacttgatcaactacttcgtgcaacccgaagacgatatcgaa cacgaagagaaacagaacaagttgaaggccttacggaataggcaggaccttttccaggaa gagggcatcctcaacttgattctggagacgatcgacaagatcaacaccatcaccacgtcg ggctacctgatgaccgccggaggggaggacgccggccagaactgggacgccatctcgggc ttcctctaccagctgctcgcggccataatcaaggggaaccacaccaactgcgcccagttc gcccagcctcatcgcctggactggcttttcagccgtctcagcagccagcaggcctccgaa ggcacagggatgctggacgttcttcactgcgtgctcatcgacagtcccgaggccctgaac atcatgaaggaagaccacatcaaggtcatcatctccctcctcgagaagcacggccgcgac cccaaggtgctggacgtgctctgctctctgtgcgtgaccggaaagggcgtggcagtgcgc agcagccagaacaacatttgcgacaacctactgcctggacgcaacctactgctacagacg aggctggttgaccacgtggccagcatgcagcccaacatattcgtggggcgggtggagggg gcggccctgttccggcgctggtactacgaggccatggtggaccactgcgagcagcggagc cacctggagccgcacctgcgcatcgggtgggccaacacggcgggctacgtgccctacccg gggggcggctccaagtggggcggcaacggcctcggggacgacctctactccttcggcttc gacggggcctgcctctggaccggtggccgcagcaacgccgtccgcaacgctccggcgccc ttcatccgcaagggcgacgtggttggctgcatcattgacctcaacgtacccgtgattagc ttcaccgtcaacggcatcaaggtgaagggctgctttcgcaacttcaacaccgacggcatg ttctacccggccatcagcttctccgcaaagctcagttgtcgcttcctgctgggcggagac cagggcaagctgcgctacggtcccccggacggccactcagccctggtggaggccctcctg ccgcagcaggtgctgaccgtggagccctgctttcagtttggagacgtgcccaagggggtc ctcttcggccccgccgccatctcggacgacgccgtcttcgtgccggcacccgtcgacacg tcggcaattgccctgcccaactacattgagtcggtgagggacaagctggcagaaaacatc cacgaggtgtggtcgatgaagaagattgacgctggctggagatacgcagaggtccgggac gacaaccgcaacgtgcatccgtgcttgacgtccttcgagcatcttccgccggccgagaag aagtacgacaccacgctggccctgcagacgctcaaaaccatcctggccctaggataccat attacagtggataaaccaccggcccgcatcaaaaccatcaagcttccgaatgacccatac ctgcagtcgaacgggtacaagcccgcccccctggatgtgggcgccatcagcctaaccccc aagatggaagaactggtcgacctgctctcggagaacacccacaacgtctgggcgcaggag cgcatccagcacggctggacctacggactcgtggagaatcagccaacaaggcgaagtcca cacttggtgccctacaagacagttgatgacatcatcaagaaggccaacagggacacagcc agtgagctggtgcgtaccctcctggcctatggctacgtgctggaacctccgactgcagac agcctcgaaggggcgcagagcaaggtctcgtccgtgaagtacgaccagcgaacctatcgg gcggagagaacctacgcagtgactgacgggaaatggtattttgagttcgaagtgctcacc ctcggtgtcatgaaggttggctgggctggccccaacttcctgccttcctgcgaacttggg ggagacgacaactcatgggcattcgatggcttcaaggctgccaagaaccacgccggcggc tccgaggtgtacgggaagcagtggcagatcggggatgtcattggctgcatgctggacctc cacgaccgcaccatcagcttctctctcaacggagagctgctccttgactcattgggtgga gagactgccttctcagacattccctgcggcgaaggcgcgtcctacgtgccagcgtgcacc ttcggtattggtcaaaaggcgaggctggtgtttggccacgacgtcaacctgctgcgctac ttcaccacctgcggccttcaagagggctatcaaccattctgcgtcaacatgaatcgcaac atgaccttctggtacaacaaggatgaggccgtctttgtcaacgtggacgatgcattccat ccgaatgttgaagtcagccgaattcctgcaggaggggaatgccctcctgccttgaagatc atccacaagttgtttgagtccgtggagaaggtcaactacgagtttctcaggctcagtctg ccggtgacatgccacgacacacttatcgaggaaattgaaaaggagcaacgctgggaagag atccgccgcaggcagaggagagcacaggcggagaggaagagcattcgtcacccagccaac ttggagcagcacatgcttcgcagtggtttcagcatgtctgacgtgaaagatcttcagcgc ggctattccgaggacgcggccgaaggggacgagatgctgcacgtggagcaccgtccgccg actccgctgcagcgccgacgctccgtgcacgccgggacactcaccaagacgcagtccttc gacgcagccaccaccctgcaggtgcccgacggctcggggagtcgcctgagggcagcgtcg agcgaggaggctctgacccggatcggacagccgcacaagggacagcgcagcaaggccacc acaccggagcccgaaggcaaagccaagcgccggggcaagtctcccttccgcttctttcgg agcaagaaggacgagaaggaggagaaggagcctgcgccagcccagcccgcccccgccgcc cccaaggcgcccacgccggccacactcgcgccgcccatgctcacggtgcgagccccgtcc gtgcagcgactcacaccagccggcagccagctgctgtgtcctccggtgccggaccgaccc agcggcctgggcgggggcggaatcccgcgcaccggcagctctcgacgcccctccttggcc ccggccccgcctcccgcggacgacaccggggaccggctggaccccagcgtacttgacctt gtggacgagtacttctacggactgcgcgtcttccccgggcaggaccctagtcacgtttac tgcggctgggtgacgaccacgtacaagtaccacgaccggagcttcagcaacgccaaagtg cgcaaggtggcctaccacgggctcagcgaggacggactcgtgcaccaagttctggagcgg cagaactgctacatggtctgcgccggtcagctagctacagagattagccatggtgaagcc ggcagtcgatctgccaaccagggcatgtatgtaggttgtcacatcgatctcgccactggc atgctcacgttcagcgctgatggccacataacccggcaccgcttcaagatggagcccggc accaagctgtaccctgcggccttcttcgaggcgaccagcaaggaggtgcttcagttcgag ctgggccacacccctaccactctgcccctgtctgcggctctgctgcacaacaccagcaga catctcacccctcagctgccacccaggctgaaggtgcagtgcgtgcaaccgtacgtgtgg gcccgcgtgcccaacgtgtcgctgcggccgcacgccctgcggctctccgaggtgcgtggc tggagcatgctctgcgaggaccccgtgtccatgctggccctccacatccccgaagaggac cgctgcatagacatcctcgaactcatcgagcacgagcgcctactcaacttccacgcgcac acgctgtccctgtacggggcgctgtgcttccagggcaaccaccgggcggcccacatgatc tgctcccacgtggacgagaagcagctcatgtacgccatccaggccgagtacctgtcgggg cctctgcgcacgggcttcaccgacctgctcatttccctgcacctcgagttccacgcctac gccaggagcctcacccagaacgagttcattgtgcccttgggcccggacataagagaactg taccaggaccccctcaaggcccactcgttcaccacgctggagtgcatctccatacggccg gagatgtccttctcggagaccagagagcaagtggactccatcgcagacctgagcactccc tacttcccagtggacgccctgaaacagtttgttatcgaagcgctggccgacgccgtcaag aaggacagccgcccgaacagagaccccattggcggaagcaacgagaacttgtttgtgccc ctgctgaagctcgcagacaagcttctgctggtgggtctgctcgacgacgaggacttgcag tggctgctctatctgctcgaccccgaaactttcgaccccaactaccggaacgccggcaat ggcggcgccctggggctgatagacatgcaggtggccgagggggtgaagctgcagatctgc tacatcctgcaccacctgtgcgacctacagatgcgccaccgcgtggaggccatcgtgtcc ttctcggatgactacgtgggaaacttgcagacggatcaactacgccggtacattgaaatc aagcagtctgaccttccatcgtctgtcgctgccaagaaaaccagggaatttcgctgctca cccaaggaacagatgcgagccatcctggggttcaagcacctggaggaggagaactgggac cagtgcccgtgtggggagggcctgcgagaggtgctgagcagcatgcacgcggaccagctg agcaggctcaaggtggccacggccgccgaggaggaggcgcccgagaaggaggccgacggg gaccggtccctgcgccagcgcctcatgcacctcgtcagcctcgtcagggcctccgaggag gagtccggaggcggagaggaacgcgtcactctgcccgaagagatcttcacgaagaaggtg gtccacattgtggtgaagtgggcagagcagtccgagtttgagaaccgggaggtgatccgg cagatgttccgcctgctgctgcgcatctacagctcggtgtcggagctgatgaacgcccta gagaacacgtacgtcatcagccacatgagcaagtcagacatcatcagcgtgctcagccac ctgggcaaggtgagggccctgctgcccgttcagatgtcttcgcaagaagaggaggtgatg cgcaaaagtctctgggccctggtgaacaaccgcatcttcttccaacacccggacctgatc cggattctgagggttaacgagaacgtgatggacgtgatgatcaacaccctgggcaagcgc gcccagacccagtcctcggggcaggcgccgcccgctgccgccccggcccccgcctccacc ccggggcaggccgccgaggcaccccacgccaacaaggacacctcccacgagatggtggtg tcgtgctgccgcttcctgtgctacttttgtcgcaccagtcgccagaaccagaaggccatg ttcgaccacctggacttcctcctagagaacagcaacattctgctctcccgaccgtcgctg cgaggctcgacgccgttggacgtggcgtacagctcgctgatggaaaactcggagctggcc ctggccctgcgagagcactacctggaaaagattgcggcgtatatgtcgcgctgcgggctc cagtccaacctggagctcatcgacaggggctacccggacgtgggctgggaccccgtggaa ggggagcgctacctcgacttcctgcgcttctgcgtctgggtcaacggggagagcgttgag gagaatgcgaacctggtgatccgcctgctcatccggcgtcccgaatgtctcggccccgcg ctgcgtggggaaggcccagggttgctcgacgccatccgagaggcggtccgcatgtcggag catattgtggcggagcgacagcagcaggcgcaggcccagggtgcagcggctgacgaggag gagtcggaagacgacattgacatgggagcggctatcttgaacttctactgcactctggtg gacttgctgggccgatgtgcacctgaggcggccaccatcgcgcagggcaagaacgaatgc gtgcgcgctagggccatcctgcgctccctggtgcctctggacgacctgctcggggccctt agcctgcggttcaccctgcagactccgcgcaagggggagtcaggcaagacgaaaagcgac ctgccccctggactgcaaccgaaccacaagcagtctatcgtcatgtttctggagagagtg tacgggctggagaatcaggacatattcttccgtctgctggaggacggcttcttgcccgac cttcgggccgccaccatgttggaccggacggacaacacagagagcgacatggccctggcg ctgaaccggtacatcggcaactcggtgctgcccatgctgatccagtactacagctacttc agcaacgcggagaactacgccagcctgctggacgccacgctccacaccgtgtaccggctt tccaaggtcaagatactcaccaagggacagcgggagaaggtctccgatttcctcgtggcc cttacaagagaaatgcagccgagcatgctcctgaggctacttcgaaagctgacggtagat gtttccgtcatcaccgagtacacaactgtcgctcttaggctgctgacattgcactacgag cgctgcaagagctactacagtgccagcggagggcagggagcctacgggacggcgtcggaa gaggagaggaggctcaccatgctcctcttcaccaacatcttcgactccctctcaaaaatg gagtacgaccccgagctgttcagcaaggccctgccgtgcctgacggcaatttcttgcgcc cttccgcccgactactcgctcactgagggccaggatgacgactggtgcaagcagggcacc cacacctcaggcccctacgtgccggagccggtcaacaccagcgggattcagctgagccag gacttgcacaatattgtgcagaggttttcggaacacttccacgacgcgtgggctactcgt aagatggaacgtggctggcagtacggagaacgctggaacgacgacgtgaaaacacaccca agactgaagccctacaaccttcttactgactatgaaaaagagcggtaccgggaccccatc cgagagctgctcaaggcgctgctggctttcggctggaagctggagctgacggactcctcg cagcgctccgctgctcccatcgctgcccaagcgccatctccgatggcctacatgccaacc cccgtggatatgtccaccctgacgttgaacaaagacatgatgaccatgtcggaacgtctt ggagagaatacccatgacatctgggcgaaaaaaatgaaagaggagttggaggccgttggg ggtggtatccacccacagcttgtgccgtatgacctgctgacggatcgtgagaagtacaag aaccgcgacagggctcaggagttcctcaagttccttcagtacgagggataccgcctctcc agcaagatgacccggcggcgcgagcgtggcggtgcccccagcgaggagcccatgtcgccc gcggtaggcgcggcgcagggcctggagcggcgcttcgccagcctgcttctggagaagctg ctgcagtacctggacgtggccgccatcaacctgaaggtgcttcgccccagcatccccttc agccgcaggaacagcttcaaggcctccagcagggacgtcaagttcttcagcaaggtggtt ctcccgctgatggaaaagtgcttcgtggcccaccgtgcctttttcctcatgtcacccacg gccacctcgaccgtgggcacggccaccatacgagaaaaggagatggtcgccagtctcttt tgcaagctgggtggtcttctgagggccaagttcagcgtgttcgggaatcaatccaagatc acagtctcctgtctccaggtgctgattcgagccaccgacgccaggaccatcgtgaagaac tgcccggacttcgttaagacgtcgatgatgacgtacttcaacaacgcggcggacgacctg gcccagacgctgttgaacctagagcaggggcgctacagccacctgcggggcaccaccatg aagacctcctcgtcgctaaactacgtccagttcgtgctgctgcccgtgctcaccgccgtc ttcgatcacctggccgccaacgagttcggcagcgatctcctgctggacgacattcaagtg gcatgctacaagattctaaacagtctgtacaccctgggcaccaggactgatctgcacggg ggaaggagctttgtgaaggccgaactggagcggcaccgaccggcgtacggcaactgcctg ggggcgtttgctgccacttttcctgttgcctttctggagccgtcacacaacaagcacaac cctcactgtatccacggcaaggcccaggaacactctctcgaggcacaggctgtgatggcc acactggagtcgagcatgcctactttggacgacctgatgggacaggtggagaagtttgtg actgccaacgggaagtactctgaacaaccctacatcattgaggtgatgcttcccatgctg tgcagctacttgccattttggtggagccaaggaccagacaatgttaatccgaccactggg aatcacgtgacgatggtgacaagcgaccacttgacgaacctgctcagaaacatcctgaac ctgctgagaaagacggtctcggtcgaaggttcaccctggatgatcacctttgcaggccac gccggacaaatagtgatcaactcctcggaggaacttttgcgtgatccgatcctgccgctc atggagaagatccaacacagcgctgacctggtgttccacaaggaggagtgcatgcgaagc tacctcaagtccagcactgacgacacttcacaggcagaagggcagctgcaagaggagttt actcttctcgtcagggacatctatgcattctttccacttctaattaaatatgtggacctc caaagaaaccattggttgaagaataatgtcaaagaagcggagctagtgtacactcgtgtg gcacacgtgttcaacatctggaacaagtcacagtatttccggagggaggaggcgaacttc atctcccagcacgagatcgacaacatggccctgatcatgccgtcctcgggccgcggaagg gccagcgtgcagaccacggacgccagccaaagtcagaagaaggagaagaaaaaaaagcgg gatggcaagagggacaaggacaaagagttggcggccagcctggtggtagcatgcctcaag cgtctgcttcccgtgggcctcaacctgtttgcgggacgcgagcaggagctcgtccagcac gccaaagagaagttcctcaacaaagaccaagacgttgacatcttcgattatgtgaagctt caacttactcttccggacaaaattgaccccagcgatgccatgagctggcagcactacctg tacagcaagctcggcagccagcgttcctcgggcagtcagattgtcccggcacaggtgtca catgaccagctagtcgaacgcatcatggacatggccaaggttctctacggccttcacatg atcgaccacccacaaggctccatgaagggggtgtaccgcagtgtagtttctacgcaacgg aagcgagccgtgattgcctgcttccgcatgatttctctgcacagccttcccaggcaccgc gccatcaatatcttcctgaagatctacaaagagctctggctagaagacgagaatgtggga caagaggagctcatagaccaccttacaacaaccttcgaggattcggagaaggagacttcg acggaggaagccgaagagaagccggatcccctggtgcagctggtcgtggccttctcccga acggccaccacggagcacagtggcgtaataccggaagatcctttgtacatgcagtatgcc ttcatattcagtcagagctgtgggggagcggaagaggaggaggaggaagaggagggggac gacgatgctggaccttccattcacgagcaagagctggagaagcagcgcctgctcttccac caggcgcgtctggccagccggggagtggcggagatggccctgctgtacatctctgcctgc aagggcgctcaaggtcccatggtgatggagacgttgaaacttggaatctcacttctcaag ggaggaaaccaggaagtgcaagtgcgcatgctgcagcacctgaaagagaagagagatgtc gggttcttcacttccattgcgggtctcatgaattcttgcagtgtgctggacctggacgcg tttgagcgcactcagaaggcggagggcctgggcgtgggctcggaaggcacggcgggagag aagaacatgcacgacgccgacttcacctgcgccctcttccgatttcttcaactcctctgc gaggggcacaacctggaatttcagaactacctcaggacgcaggccggcaacaccacaaca gtgaatgttgttatcagcaccgttgattacttgctcaggttgcaggaatctgtcatggac ttctactggcattactcaagtaaagaagttattgaccaacctggcaaggacaacttttgc cgggccataactgtagcaaaacaagttttcaacactctcactgagtttatacagggtccc tgctccttgaaccagcaggccttggcacacagtcgtctctgggacgcagtcggcggcttc ctcttcctcttcgcccacatgcaggacaagctctccaagaattccagtcagttggacttg ctcaaagagcttctggaactacagcaggaaatgatcattatgatgctcagcatgctggaa ggaaacgtcatgaatggcaccattggaaagcaaatggtagacacacttgtggaatcggca tcaaacgtggagatgattctacgcttctttgacatgttcttgaaactcaaggaactgacc tcatccagctcattccaggaaatagattccaataactctggctggattactcccaaagat tttcagaaagcaatggagcaacagaagatatacaatccagatgagattgcctttttgatg agctgttgcgagccaaacattgatgatttgatcgactaccgggagttcaccgagcgtttc cacaaccccgccaaggatatcggatttaatgtggctgtactattgacaaacctttctgaa cacatgccgaacgacccaaggcttcaccgtttcctggagaccgctagcagcgtgttgaac tattttgagccattcttgggacgcattgagattatgggtggcagcaaaaggattgaaaga gtttactttgaaatcaaggagtccacaattgaccaatgggaaaaacctcaaataaaggaa tcaaagcgggccttcttctatagcattgtcaccgagggaggagacaaggagaaactagaa gcatttgtgaacttctgcgaagatgcaatatttgagatgcagcatgcaagcagcatatcc aacgaagacaccgaggaacctccagcgaaggccgaaccttacacgtttctgggagcagag gagtcgaggcctccgggtccgatggagccactgaagcagggcttctggctgctgcgggac gctataggggcactgctgtcggtactgcggccctcctacctgaagcgccagttccaggcg cttcgtcgaaagagcctgggagaactcctcatgggcctgttccgcttctccttcttcggc ttcttctacgtcatctggctgggcctccactgctccaagagcctagtgggaatcatcatc cgcctgatgggaggccaaccgctggccggggacactctgccagaagaggacatttccaag ggggcgctgctgctgccccagaggccccttgccgccctggaaggcatcccgagccagatg ggctctctcccggcggacgcagagaccccgacgcacgcgagggtatccggtcacgaagcc aacaagctggatgaggacggcgatctcaagcacaacgcccccaaagcacctatgagccct caggcaagcacagacctggctgaccaggaccaagtgggagacgaggaacacgccaaggga gcacccggagtcaagtcaccagatggtgaacttcccgacggtctgactgccgacggacag ataagccatctggatggagatatcaagctgaaagacatggagcagctccaaggaagcatg gatgccaagcgtgcgctgccgggccccgaggccatgcccccgtcccccctgctgatgccc cccatggcctcccctgaggcagctaagccctccgaaaccccccctgtggccgccatcgac ctcagcgagtacagccagaagattgtgagtttcctggcccgcaatttctacaacatgaag tacattgccctggtcttggcattctttatcaactttattctgctgttttataaggtgact acgggtgaggaagatgccgacgcaggcagtggcagtgacgacgaagcagagcccgcctcg accgtcggcaatggcctggccgacctgttgagcaacgcgacggaggccgtggcctctggt tcagacagcgaggacgaagacctggaggagtgggtcatcattgaggagaagttcttctac ctagaaccggtcatccgcttcatggccttattccactccctggtctccttctgcatgctc atcgcatactaccacctcaaggttcccttggccatcttcaagcgagaaaaggaagtagca cgtgccatggagtttgacggcctctacatcagcgaggaaccggccgaagacgatatacgc acccgctgggacaagctggtcatcagcaccaagtcctttcctgtgaactactgggacaaa tttgtcaagaaacgggtgcgacagaagtactctgaaacgtacgacccagaggccctgagc aacgtcctgggcatggacaaaagtggctccttctcgcaggaacaggaagagtccggaggc ctgattcccttcattacaaatgcagactggaaataccagatctggaaatccggagtcaca atcaccgacaactcgttcctgtacaacctgtggtacttcctgttttcggtgatgggcaac ctgaactacttcttttttgcggcacacctgctcgacgtggccgtgggcttcaagaccctg cgcaccatcctgcagtcggtcacccacaacgggaagcagctggtgctaacggtgatgctt ctcaccatcatcgtctacatctacactgtgattgcattcagcttcttcaggaagttctac atacaggaggaagacgatcaagtcgaccccaagtgccacagcatgctctcgtgtttcgtg ttccacctgtacaagggtgtacgagccggtggtggcattggtgacgaaatcggcccgcct gacggcgacgactacgaagtctaccgcataattttcgacatcaccttcttcttctttgtc atcgtcattctgctcgcaatcatccaaggtctcatcattgacgcctttggcgagctgaga gaccaacttcagagcgttgtcgatgacatggagtcaaactgcttcatctgtggaatcggc aaagactactttgacagagtcccgcacggcttcgacacccatgtacaaaaggagcacaat ctggccaactacatgtttttcttgatgcatctgatcaacaaacctgacacggagtacacc ggtcaagagacgttcgtgtgggagctgtaccagaagcgctgctgggacttcttccccgtg ggcgactgcttcaggaagcagtacgaggacgagctgatgggcgccggttaa

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