Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101956709
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Entry
101956709 CDS
T10664
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti00270
Cysteine and methionine metabolism
iti00480
Glutathione metabolism
iti01100
Metabolic pathways
iti01240
Biosynthesis of cofactors
iti04216
Ferroptosis
Module
iti_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101956709 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101956709 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101956709 (Gclc)
Enzymes [BR:
iti01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101956709 (Gclc)
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
101956709
NCBI-ProteinID:
XP_005318611
UniProt:
I3LXJ9
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All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETKRYADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSVLEENQALCTITSFPRLGCPGFTLPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPDDEAAKASKPDHIYMDAM
GFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVIS
ASVDDRTREERGLEPLKKNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYQQLLQE
GIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIG
WRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQ
GMFYFRKDICKGGNAVVDGCGKAQSSSEPATEEYTLMSIDTIINGKEGVFPGLIPILNSY
LENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIAHHPDYKQDSIITDEMNYSL
ILKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgcctctgagctgggaggagaccaagcgctacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccatgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataaaaaagtccagttggtcctgtctggagaagatgttcttgaaactttacaagag
aagggggaaagaacaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaaggaacacctgggcagccctatggaggaacgatgtctgagttcaacacagtt
gaggacaacatgagaaaacgccggaaggaggctacttctgtactagaagaaaatcaggct
ctttgcactataacttcatttcccagattaggctgtccggggttcaccctgcctgagtac
aaacccaacccagttgaaggaggagcttccaagtccctcttctttccagatgaagcgata
aacaagcacccccgcttcagtaccttaacaagaaatatccggcataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaacacaccatctccattcatagaaaca
tttccagatgatgaggcagcaaaggcttccaagccagatcatatttacatggatgccatg
ggatttgggatgggaaattgctgtcttcaggtgacattccaagcctgcagcatatctgag
gcaagatacctttatgatcagttggccactatctgtccaattgttatggctttgagtgct
gcatctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatttct
gcatctgtagatgatagaactcgagaggagagaggactggagccactgaagaagaataat
tataggattagtaaatcccgatatgattcaatagacagctacttatctaagtgtggtgag
aagtacaatgacatcgacttgaccatagataaagaaatctaccagcaactgcttcaggaa
ggcattgatcatctcctggcccaacatgttgcccatctctttattagagacccactgact
ctgtttgaggagaaaatacatctggatgatgccaatgagtctgaccattttgagaatatt
cagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagacattgga
tggagagtagaattccgacccatggaggtgcagttaacagactttgagaactctgcctat
gtggtgtttgtggtccttctcaccagggtgatcctatcatacaaattggattttctaatt
ccactgtcaaaggttgatgaaaacatgaaagtagcacagaaacgagatgctgtcctgcag
ggaatgttttatttcaggaaagatatttgcaaaggtggtaatgctgtagtggacgggtgt
ggcaaagcccagagcagctcggagccagctacagaggagtacaccctcatgagcatagac
accatcatcaatgggaaggaaggtgtgtttcctggactcataccgattctgaactcttat
cttgaaaacatggaagtggatgtggataccagatgtagtattctgaactacttaaagcta
attaagaagagagcgtctggtgaactgatgacggttgctagatggatgagagaatttata
gcacaccatcctgactacaagcaagatagcataataactgatgaaatgaactatagcctt
attttgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttactaggacca
gcatttaggaaagtaaaatacagtggaagtaaaactgactcttccaactaa
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