Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101956917
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Entry
101956917 CDS
T10664
Symbol
Pdgfra
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01521
EGFR tyrosine kinase inhibitor resistance
iti04010
MAPK signaling pathway
iti04014
Ras signaling pathway
iti04015
Rap1 signaling pathway
iti04020
Calcium signaling pathway
iti04072
Phospholipase D signaling pathway
iti04144
Endocytosis
iti04151
PI3K-Akt signaling pathway
iti04510
Focal adhesion
iti04540
Gap junction
iti04630
JAK-STAT signaling pathway
iti04810
Regulation of actin cytoskeleton
iti05163
Human cytomegalovirus infection
iti05200
Pathways in cancer
iti05206
MicroRNAs in cancer
iti05214
Glioma
iti05215
Prostate cancer
iti05218
Melanoma
iti05230
Central carbon metabolism in cancer
iti05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101956917 (Pdgfra)
04014 Ras signaling pathway
101956917 (Pdgfra)
04015 Rap1 signaling pathway
101956917 (Pdgfra)
04630 JAK-STAT signaling pathway
101956917 (Pdgfra)
04020 Calcium signaling pathway
101956917 (Pdgfra)
04072 Phospholipase D signaling pathway
101956917 (Pdgfra)
04151 PI3K-Akt signaling pathway
101956917 (Pdgfra)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101956917 (Pdgfra)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101956917 (Pdgfra)
04540 Gap junction
101956917 (Pdgfra)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101956917 (Pdgfra)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101956917 (Pdgfra)
05206 MicroRNAs in cancer
101956917 (Pdgfra)
05230 Central carbon metabolism in cancer
101956917 (Pdgfra)
05231 Choline metabolism in cancer
101956917 (Pdgfra)
09162 Cancer: specific types
05214 Glioma
101956917 (Pdgfra)
05218 Melanoma
101956917 (Pdgfra)
05215 Prostate cancer
101956917 (Pdgfra)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101956917 (Pdgfra)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101956917 (Pdgfra)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101956917 (Pdgfra)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
iti04090
]
101956917 (Pdgfra)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101956917 (Pdgfra)
Protein kinases [BR:
iti01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
101956917 (Pdgfra)
CD molecules [BR:
iti04090
]
Proteins
101956917 (Pdgfra)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101956917
NCBI-ProteinID:
XP_005320067
UniProt:
I3MH41
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSHQAFLVFGCLLTGPGLILCQLSLPSILPNENEKVVQLNASFSLRCFGESEVSWQYP
MSEEENPNVEIIDEENNSGLFVTVLEVASASAAHTGLYTCYYNHTQTEESEIEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVILRNSEGLVPASYDSKQGFNG
TFSVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGVTMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFVEIKPTFGQLEAVNLHEVRHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSSGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTVLANNVSNIITEIYPRG
KSTVEGRVTFAKVEETIAVRCLAKNLLGSGNRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatcaggccttcctggtcttcggctgtctcctcacagggccgggccta
atcctctgccagctttcattaccctccatccttccaaatgagaatgaaaaggttgtgcag
ctgaatgcatccttttctctgcggtgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcatagatgaagagaacaacagtggcctt
tttgtgacagtgctggaagtggccagtgcctcggcggcccacactggcttgtacacttgc
tattacaaccacactcagacagaagaaagcgagattgaaggcaggcacatttacatctat
gtgccagacccggatgtggcctttgtgcctctagggatgacagattatttagtcatcgtg
gaagatgatgattctgccatcataccctgccgtaccacagacccggagactcctgtgatc
ttacgcaacagtgagggactggtgcctgcctcttatgacagcaaacagggcttcaatggg
accttcagtgtggggccctacatctgtgaggccaccgtaaaagggaagaagttccagacc
ataccctttaacgtttatgctttgaaagcaacatcagaactggatctagaaatggaggct
ctgaaaactgtgtataagtcaggagaaacgatcgtggttacctgcgctgtttttaacaat
gaggtggtcgacctgcagtggacttaccctggagaagtgaaaggcaaaggagtcacgatg
ctggaggaaatcaaagtcccatccatcaaattggtgtacacattgacggtccctgaggcc
acggtgaaagacagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gaaatgaagaaagtcaccatttctgtccatgagaaagggtttgttgaaatcaaacccacc
tttggccagctggaagctgtcaacctgcatgaagtcagacattttgtggtggacgtgcag
gcctacccccctcccaggatatcttggctgaaggacaacctgactctgattgaaaatctc
actgagatcaccactgatgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagatagtggccattatactataatagttcaaaatgaagat
gatgtgaagagctatacttttgaactattaactcaagttccatcctctattctggatttg
gtcgacgaccatcatggctccagcggaggacagactgtgaggtgcacggctgagggcaca
cctcttcccgacattgagtggatgatctgcaaggatattaaaaaatgtaataatgaaacg
tcatggacagtcttagccaacaatgtctcaaatatcatcacggagatctaccctcgaggc
aagagtaccgtggagggccgagtgacatttgccaaagtagaggagaccattgcagttcga
tgcctggctaagaatctccttggttctgggaaccgagagctgaagctggtggctcccacc
ctgcgttctgagcttacggtggcagccgcagtcctggtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaaacagaaaccaaggtatgaaattcgctggagg
gtcattgaatcaatcagccccgatggacatgaatatatttatgtggacccgatgcagcta
ccttatgactcgagatgggaatttccaagagatggactagtgcttggtcgcatcttggga
tctggtgcatttgggaaagtggttgaaggaacagcctatggattaagccggtcccagcct
gttatgaaagtagcagtgaagatgctcaaaccgactgccaggtccagtgaaaaacaagct
ctcatgtctgagctgaagataatgactcacctggggccacatttaaacatcgtcaacttg
ctgggagcctgtactaagtcaggccccatctacatcatcactgagtactgtttctatggg
gatctggtcaactatttgcataagaatagggatagcttcctgagccgccacccagagaag
ccaaagaaagagctggacatctttggattgaaccctgctgatgagagcacacgcagttac
gtgattctatcttttgagaacaatggtgattacatggacatgaagcaagccgacactaca
cagtacgtccccatgttggaaagaaaagaggtctccaagtattcggacatccagagatca
ctgtacgatcgcccggcctcgtataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgacaactcagaaggccttactttgttggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttccaaaaattgtgtccaccgggatctggct
gctcgcaatgtcctcctagcacaagggaagattgtgaagatctgtgactttggcctggcc
agggacatcatgcacgattccaactacgtgtcgaaaggcagtaccttccttcctgtgaag
tggatggctcccgagagcatctttgacaacctctacaccacgctgagcgatgtctggtct
tatgggattctgctctgggagatcttttctcttggtggcacaccctaccctggcatgatg
gtggattctaccttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gccaccagtgaagtctatgagatcatggtgcagtgctggaacagtgagccagagaagaga
ccctccttctaccacctgagcgagatagtggagaatcttctgcctggacaatataaaaag
agttatgaaaaaattcacctggacttcctgaagagtgaccatcccgctgtggcacgcatg
cgtgtggactcggacaacgcatacattggtgtcacctacaaaaatgaggaagacaagctg
aaggactgggaaggtggcctggatgagcagagactgagcgcagacagtggctacatcatc
cctctgcctgacattgaccctgttcctgaggaggaagacctgggcaagaggaacagacac
agctcacagacctctgaagagagtgccattgagacaggttccagcagctccaccttcatc
aagagagaggacgagaccattgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtggaggacagcttcctgtaa
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