Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101960744
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Entry
101960744 CDS
T10664
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01521
EGFR tyrosine kinase inhibitor resistance
iti01522
Endocrine resistance
iti04010
MAPK signaling pathway
iti04014
Ras signaling pathway
iti04015
Rap1 signaling pathway
iti04066
HIF-1 signaling pathway
iti04068
FoxO signaling pathway
iti04081
Hormone signaling
iti04114
Oocyte meiosis
iti04140
Autophagy - animal
iti04144
Endocytosis
iti04150
mTOR signaling pathway
iti04151
PI3K-Akt signaling pathway
iti04152
AMPK signaling pathway
iti04211
Longevity regulating pathway
iti04213
Longevity regulating pathway - multiple species
iti04510
Focal adhesion
iti04520
Adherens junction
iti04550
Signaling pathways regulating pluripotency of stem cells
iti04730
Long-term depression
iti04913
Ovarian steroidogenesis
iti04914
Progesterone-mediated oocyte maturation
iti05200
Pathways in cancer
iti05202
Transcriptional misregulation in cancer
iti05205
Proteoglycans in cancer
iti05214
Glioma
iti05215
Prostate cancer
iti05218
Melanoma
iti05224
Breast cancer
iti05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101960744 (Igf1r)
04014 Ras signaling pathway
101960744 (Igf1r)
04015 Rap1 signaling pathway
101960744 (Igf1r)
04066 HIF-1 signaling pathway
101960744 (Igf1r)
04068 FoxO signaling pathway
101960744 (Igf1r)
04151 PI3K-Akt signaling pathway
101960744 (Igf1r)
04152 AMPK signaling pathway
101960744 (Igf1r)
04150 mTOR signaling pathway
101960744 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
101960744 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101960744 (Igf1r)
04140 Autophagy - animal
101960744 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
101960744 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101960744 (Igf1r)
04520 Adherens junction
101960744 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
101960744 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101960744 (Igf1r)
04914 Progesterone-mediated oocyte maturation
101960744 (Igf1r)
09156 Nervous system
04730 Long-term depression
101960744 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
101960744 (Igf1r)
04213 Longevity regulating pathway - multiple species
101960744 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101960744 (Igf1r)
05202 Transcriptional misregulation in cancer
101960744 (Igf1r)
05205 Proteoglycans in cancer
101960744 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101960744 (Igf1r)
05214 Glioma
101960744 (Igf1r)
05218 Melanoma
101960744 (Igf1r)
05215 Prostate cancer
101960744 (Igf1r)
05224 Breast cancer
101960744 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101960744 (Igf1r)
01522 Endocrine resistance
101960744 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101960744 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
iti04090
]
101960744 (Igf1r)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101960744 (Igf1r)
Protein kinases [BR:
iti01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101960744 (Igf1r)
CD molecules [BR:
iti04090
]
Proteins
101960744 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
101960744
NCBI-ProteinID:
XP_005320151
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHQECLGSCH
APDNDTACVACRHYFYEGVCVPACPPDTYRFEGWRCVKRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTVMDTYNMTDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EARPENSIFLKWAEPENPNGLILMYEIKYGSQIEDQRECVSRQDYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKTTYENFIHLIIALPVAILLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYIPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERRPYAHMNGGRTDERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgttcctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtggcccgggcattgacatacgc
aacgactatcagcagctgaagcgcctagagaactgcacggtgatagagggctacctccac
atcctgctcatctccaaggctgaggactaccgcagctaccgtttccccaagctcacagtc
atcactgaatacttgctgctgttccgagtggctggcctagagagcctcggagacctcttc
ccgaacctcacagtcatccgcggctggaaacttttttacaactacgccctggtcatcttt
gagatgactaatctcaaggatattgggctttataacctgaggaacattactaggggtgcc
atcaggattgaaaaaaatgctgatctctgttacctctctacagtggactggtctttgatc
ctagatgcagtgtctaataattatattgtggggaacaagcccccaaaggaatgtggggac
ctgtgtccagggaccttggaggagaagccattgtgtgagaagaccaccatcaataatgag
tacaactaccgctgttggaccacaaatcgctgccagaaaatgtgcccgagcgtgtgcgga
aagcgagcttgcaccgagaacaatgaatgctgccaccaggaatgcctgggcagctgccac
gcacccgacaatgacacagcctgtgtcgcctgccggcactacttctatgagggcgtgtgt
gtgcctgcctgcccgcccgacacctacaggttcgagggatggcgctgcgtgaagcgcgac
ttctgtgccaacatcctcagcgctgagagcagtgactctgagggctttgtcatccatgac
ggcgagtgcatgcaggagtgcccctcaggcttcatccgcaacggcacccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaagtctgtgaagaagagaagaaaacaaagact
attgattctgttacttctgctcagatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgacgaggcaataacattgcctcagaactggagaacttcatggggctc
atcgaggtggtgaccggctatgtgaagatccgccattctcatgccttggtctccttgtcc
tttcttaagaaccttcgtcagatcttaggggaggagcaactggaagggaactattccttc
tatgtcttggataaccagaacttgcagcagctatgggactgggaccaccgcaacctgacc
atcaaatctgggaaaatgtacttcgctttcaatcccaaactgtgtgtttctgaaatttac
cgcatggaggaagtaacagggacaaaagggcgccaaagcaaaggagacataaacaccaga
aacaatggagaaagagcctcctgtgaaagtgatgtcctacatttcacatccactaccacg
tggaagaaccgcattatcataacctggcaccggtaccggcccccggactacagggatctc
atcagcttcactgtttactacaaggaggcaccctttaaaaatgtcacagaatatgatggg
caggatgcctgtggctccaatagctggaacatggtggacgtggaccttcctcccaacaaa
gatgtggaacctggcattttactgcatgggctgaagccctggactcaatacgcagtctat
gtcaaggccgtgaccctcaccatggtggagaatgaccacattcgtggggccaagagtgaa
atcttgtacattcgtaccaatgcttcagttccttccattcccctggatgtcctttcagca
tcgaactcctcttctcagctgattgtgaaatggaaccccccatctctgcccaacggtaac
ctgagttactacattgtgagatggcagcgacagcctcaggacggctacctgtaccggcat
aattactgttccaaagacaaaatccccatcaggaagtatgctgatggcaccattgatgtc
gaagaggtaacagagaatcctaagactgaagtgtgtggtggtgagaaagggccttgctgc
gcttgccctaaaactgaagctgagaagcaagctgagaaggaggaggctgaataccgcaaa
gtctttgagaatttcctgcataactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacagtgatg
gacacctacaatatgacagatccagaagaacttgagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtcatctctaacctccggccttttactttgtaccgc
attgatattcacagctgtaatcatgaggctgagaagctgggctgtagtgcctctaacttt
gtctttgccagaaccatgcctgcagaaggagcagatgacattcctggcccagttacctgg
gaggcaaggcctgagaactccatctttttaaagtgggcagaacctgagaaccccaatgga
ttgattctaatgtatgaaataaaatacggatcacaaattgaggatcagcgagaatgtgtg
tccagacaagattacagaaaatatggaggggccaagctcaaccggctaaacccagggaat
tatactgcccggattcaggctacctctctctctgggaatgggtcatggacagatcctgtg
ttcttctatgtcccagccaaaacaacgtatgagaatttcatccatctgatcatcgctctg
ccggtcgccatcctgttgatcgtgggagggctggtgataatgctgtatgtcttccataga
aagaggaataacagcaggctggggaatggagtgctatatgcctctgtaaacccagagtac
ttcagcgcagccgatgtgtacattcctgacgagtgggaggtcgctcgagagaaaattacc
atgagccgggagctggggcaggggtccttcgggatggtctatgaaggagttgccaagggt
gtggttaaagatgaacctgaaaccagggtggccatcaagacagtgaacgaggctgccagc
atgcgtgaaaggattgagtttctgaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtggtgtcccagggccagccaacgctggtcatcatggaa
ctgatgacacggggggatctcaaaagttatctcagatctctgaggccagaaatagagaat
aacccagtccttgcacctccaagcctaagcaagatgatccagatggctggagagattgca
gatggtatggcatatctcaatgctaacaagtttgtccacagagaccttgctgcccgaaat
tgcatggtggccgaagatttcacagtcaaaattggagattttggtatgacaagagatatc
tatgagacagactattaccggaaaggagggaaagggttgctgcctgtgcgttggatgtct
cctgagtccctcaaggatggagtcttcaccactcattcagacgtctggtccttcggggtt
gtcctctgggagattgccacactggccgagcagccgtaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggtggccttctagacaagccggacaactgccccgacatg
ctgtttgagttgatgcgcatgtgctggcagtacaaccccaagatgagaccttccttcctg
gaaatcatcagcagcatcaaagacgagatggaacctggttttcgggaggtctccttctac
tacagtgaggagaacaagccacctgaacctgaggagctggacctggagcctgaaaacatg
gagagtgtccccctggacccctcggcctcatcgtcatccctgccactgcccgacagacac
tcaggacacaaggctgagaatggcccaggccctggggtgctggttctccgagccagcttc
gatgagagacggccttacgcgcacatgaatggaggacgcacagatgagagagccttgccg
ctgccccagtcttcaacctgctga
DBGET
integrated database retrieval system
