Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101963145
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Entry
101963145 CDS
T10664
Symbol
Atp2a2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti04020
Calcium signaling pathway
iti04022
cGMP-PKG signaling pathway
iti04024
cAMP signaling pathway
iti04148
Efferocytosis
iti04260
Cardiac muscle contraction
iti04261
Adrenergic signaling in cardiomyocytes
iti04380
Osteoclast differentiation
iti04919
Thyroid hormone signaling pathway
iti04972
Pancreatic secretion
iti05010
Alzheimer disease
iti05017
Spinocerebellar ataxia
iti05022
Pathways of neurodegeneration - multiple diseases
iti05410
Hypertrophic cardiomyopathy
iti05412
Arrhythmogenic right ventricular cardiomyopathy
iti05414
Dilated cardiomyopathy
iti05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
101963145 (Atp2a2)
04024 cAMP signaling pathway
101963145 (Atp2a2)
04022 cGMP-PKG signaling pathway
101963145 (Atp2a2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101963145 (Atp2a2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101963145 (Atp2a2)
09153 Circulatory system
04260 Cardiac muscle contraction
101963145 (Atp2a2)
04261 Adrenergic signaling in cardiomyocytes
101963145 (Atp2a2)
09154 Digestive system
04972 Pancreatic secretion
101963145 (Atp2a2)
09158 Development and regeneration
04380 Osteoclast differentiation
101963145 (Atp2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101963145 (Atp2a2)
05017 Spinocerebellar ataxia
101963145 (Atp2a2)
05022 Pathways of neurodegeneration - multiple diseases
101963145 (Atp2a2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101963145 (Atp2a2)
05412 Arrhythmogenic right ventricular cardiomyopathy
101963145 (Atp2a2)
05414 Dilated cardiomyopathy
101963145 (Atp2a2)
05415 Diabetic cardiomyopathy
101963145 (Atp2a2)
Enzymes [BR:
iti01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
101963145 (Atp2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
101963145
NCBI-ProteinID:
XP_005329666
UniProt:
A0A287D7N7
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTAKAFTGREFDEL
SPPAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggtcatttcggcgtcaacgag
agcacggggctgagtctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttgccggccgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaatattgttactggcagcatgtatatcttttgttttggcttggtttgaagaa
ggagaagaaacaattacagcctttgtagaacctttcgtgattctacttatattagtagcc
aatgcaattgtgggtgtttggcaggaaagaaatgctgagaacgcaattgaagcccttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtgcagaggatt
aaagctaaagacatagttcctggtgatatcgtagaaattgctgttggtgacaaagttcct
gctgatataagattgacttccatcaaatcgacaactttgagagttgaccagtcgattctc
actggtgagtctgtttcagttattaagcacaccgaccctgttcctgacccacgggctgtc
aaccaagataaaaagaatatgctgttttctggtacaaacattgctgctgggaaagccatg
ggagtggtggtggcaactggagtcaacactgaaattggcaaaatcagggatgaaatggtt
gcaacagaacaggagagaacaccccttcagcagaaactggatgagtttggggaacagctt
tccaaagtcatttcccttatttgcattgcagtctggatcataaatattgggcactttaat
gacccagttcacggtggctcctggatcagaggtgctatctactactttaagattgcagtg
gccctggctgttgcagccatccctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgaagaatggcaaagaagaatgccattgtccgaagcctcccttctgtggaa
actcttggttgtacttctgttatctgctcagacaagactggcacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacagagttgaaggtgatagttgttcactcaat
gagtttaccataaccggatcaacatatgcacccattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtctggtagaattagcaacaatttgtgctctttgt
aatgactctgctttggattataatgaggcaaaaggtgtgtacgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgatactgaattgaag
ggtctttctaaaatagaacgggcaaatgcctgcaactcggtcattaaacagctgatgaaa
aaggaattcactctcgagttttcacgcgataggaaatcaatgtcagtttattgtacacca
aacaaaccaagccggacatccatgagcaagatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttgggagtacgaaggttcctatgactcctggagtc
aaacagaagatcatgtctgtcattcgggagtggggaagtggcagcgacactctacggtgc
ctggccctggccactcatgacaaccctctgcgaagagaagagatgcacttggaggactct
gccaacttcattaagtatgagaccaatctgacctttgtgggctgcgtgggcatgctagat
cctcccagaattgaagtggcctcctctgtgaagctgtgccggcaagcaggaatccgtgtt
atcatgatcacaggggacaacaagggcactgctgtggccatctgtcgccgcatcggcatc
tttggccaggatgaggatgtgacagcaaaggcttttacaggccgcgagtttgatgaactc
agccccccagcccaaagagacgcctgcttgaacgcccgctgctttgctagagtggagcct
tcccacaagtccaaaatcgtggagtttcttcagtccttcgatgaaattacagccatgact
ggcgatggtgtgaatgatgctcctgctctaaagaaagctgagattggcattgccatgggc
tctggcactgcagtggctaaaactgcctctgaaatggtcctggcggatgacaacttctct
accatcgtcgctgctgtggaagagggacgggccatctacaacaacatgaagcagttcatt
cgctacctcatctcctcgaatgtaggggaagtcgtctgtattttcctgacagcagccctt
gggtttcctgaggctttaattcctgtccaactgctctgggtcaacctggtgaccgatggc
ttgcctgctactgcactagggttcaaccctcctgacctggacatcatgaataaaccaccc
cggaacccaaaggagccacttatcagtgggtggctgtttttccgttacctggctattggc
tgttacgtcggcgctgctaccgtgggtgctgctgcctggtggttcatcgctgctgatggt
ggtccaagagtgtccttctaccagctgagtcatttcctccagtgtaaggaggacaaccca
gactttgaaggagtggattgtgcaatctttgagtccccgtacccaatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaatgctctcaacagtttatctgaaaaccagtcc
ttgctgaggatgcccccttgggagaacatctggcttgtgggctccatctgcctgtctatg
tcactccacttcctgatcctctatgtggaacccttgccacttatcttccagatcacaccg
ctgaatctcacccagtggctgatggtgctgaaaatctccttgcctgtgattctcatggat
gagacactcaagtttgtggcccgaaactacctggaacctgcaatactggagtaa
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