Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101963175
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Entry
101963175 CDS
T10664
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti04217
Necroptosis
iti04380
Osteoclast differentiation
iti04620
Toll-like receptor signaling pathway
iti04621
NOD-like receptor signaling pathway
iti04630
JAK-STAT signaling pathway
iti04658
Th1 and Th2 cell differentiation
iti04659
Th17 cell differentiation
iti05145
Toxoplasmosis
iti05160
Hepatitis C
iti05161
Hepatitis B
iti05162
Measles
iti05164
Influenza A
iti05165
Human papillomavirus infection
iti05167
Kaposi sarcoma-associated herpesvirus infection
iti05168
Herpes simplex virus 1 infection
iti05169
Epstein-Barr virus infection
iti05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101963175 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101963175 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101963175 (Tyk2)
04621 NOD-like receptor signaling pathway
101963175 (Tyk2)
04658 Th1 and Th2 cell differentiation
101963175 (Tyk2)
04659 Th17 cell differentiation
101963175 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
101963175 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101963175 (Tyk2)
05160 Hepatitis C
101963175 (Tyk2)
05171 Coronavirus disease - COVID-19
101963175 (Tyk2)
05164 Influenza A
101963175 (Tyk2)
05162 Measles
101963175 (Tyk2)
05168 Herpes simplex virus 1 infection
101963175 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
101963175 (Tyk2)
05169 Epstein-Barr virus infection
101963175 (Tyk2)
05165 Human papillomavirus infection
101963175 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101963175 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101963175 (Tyk2)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101963175 (Tyk2)
Protein kinases [BR:
iti01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101963175 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
101963175
NCBI-ProteinID:
XP_021589527
LinkDB
All DBs
Position
Unknown
AA seq
1181 aa
AA seq
DB search
MPLCQKGAAAKGSKPHRDRAQPMADMGGLKVLLHWAGPRGGEPWVTFSKTSLTAEEVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILEVSRDTSLTLYFRMRFYFRNWHGMNPQE
PAVYRCGLPGAETSSEPTEQGVQLLDPASFEYLFEQGKHEFVNDVVSLWELSSEEEIHHF
KNESLGMAFLHLSHLALQRGVPLEEVAKEISFKDCIPLSFRQQIRQHNALTRLRLRNVFR
KFLHAFQPGHLSQQMVMVKYIATLEHLAPRFGTERIPVCHLELLSQAEGEPCYIQDSRRA
SADHNLEPALGSPTHEVLVTGTGGIQWRPVQVEVSSDVNDSSRNSQTHLSGKKAKAREAG
GQPANRPREPPWTYFCDFQDITHLVLKGCRVTIYQQDNKCLELRLPSRAAALSFVALVDG
YFRLTADSSHYLCQEVAPPRLVMSIQEGIHGPLLEPFVQAKLQPEEGLYLIHWSTVHLHR
LILTVAQPEPVPGVQSLRIRKFPIEQQDGAFMLEGWGRSFASVQELRGALQGCSLRAGDD
CFSLRRCCLPQPGEISNLIIMRGSRASSRPLNLSQLSFHRIHQDEITQLSHLGQGTRTNV
YEGLLRVGGPEEGKADGGDSPKPGGGCGQQLRVVLKVLDPSHHDIALAFYETASLMSQVS
HAHLAFVHGVCVRGSENIMVTEYVENGPLDVWLRREKGHVPMTWKVAVAQQLASALSYLE
DKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLPA
GATSLCTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHRLPEPSCPELATITS
QCLTYERALRPSFRTILRDLTQLQPHDLVDVSTINPDSPVSDPTVFHKRYLKKIRDLGEG
HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILRTLYHEHIVKYKGCC
EDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEGMAYLHAQHYIHRDLAA
RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWS
FGVTLYELLTYCDSSQSPPSKFLELIGLTQGQITVLRLTELLERGERLPRPERCPCEIYH
LMKNCWEAESSFRPTFQNLIPILKMVHEKYQGQAPSVFSVC
NT seq
3546 nt
NT seq
+upstream
nt +downstream
nt
atgcctctctgtcagaaaggagctgctgcaaagggcagcaagccccatagggacagagct
cagcccatggctgacatgggaggtttgaaggtacttctgcactgggctggccctagaggt
ggagagccctgggtcacctttagcaagacctcactgacggccgaggaagtctgcatccac
atcgcacacaaagtcggcatcactccaccctgcttcaatctctttgccctctttgatgcc
caggcccaagtctggctgcccccaaaccacatcctagaggtctccagagatacaagtctg
acactgtatttccgtatgaggttttatttccgaaactggcatggcatgaatcctcaggag
ccagctgtataccgctgtggactcccaggggctgagacttcctcagaaccgacagagcag
ggggtgcaactcttggacccagcctcatttgagtacctctttgaacagggcaagcatgag
tttgtgaatgatgtggtatcactgtgggagctgtcaagtgaggaggagatccaccacttt
aagaatgagagcctgggcatggcctttctgcacctctcccacctcgctctccaacgtggc
gtccccctggaagaggtggccaaggagatcagcttcaaggactgcatcccgctctccttc
cggcagcagatccggcagcacaacgcccttacacggctgcgcctgcgcaatgtcttccgc
aagttcctgcatgccttccagccaggccacctctctcagcagatggtcatggtcaaatac
atagccaccctggagcatctggccccccgctttggcactgaacgcatacctgtgtgtcac
ctggagctactgtcccaggccgagggagagccctgctacatccaggacagcaggcgggcc
tccgcggaccacaacctggagcctgccttgggatcccccacccacgaggtactggtgaca
ggcactggtggcatccagtggcggccagtacaggtggaggtttctagtgacgtcaacgac
agcagcaggaattcccaaacccacctgtctgggaagaaagccaaggcccgtgaggcaggt
ggccagccagcaaacaggccgagggagccaccctggacttacttctgtgacttccaggac
atcacgcacctggtgctaaaagggtgccgtgtcaccatctaccagcaagacaacaagtgc
ctggagctgagactgccttcccgggccgcggccctgtccttcgtggcgctggtggacggc
tacttccgcctgacagcagactccagccattacctgtgccaggaggtggctcccccacgg
ctagtgatgagcatccaggagggtatccatgggcccctgctggagccctttgtgcaagcc
aagctccagccagaggagggcctctaccttatccactggagcaccgtccacctgcaccgc
cttatcctcacagtggcccagcctgagccggtacctggagtgcagagcttgcgcatccgg
aagttccccattgagcagcaggacggggccttcatgctggagggctggggccgctccttt
gccagtgtgcaggagctgcggggagccctgcagggctgctccttgcgggctggggacgac
tgtttctctctgcgtcgctgctgcctgccccagcccggagaaatctccaacctcatcatc
atgcgcggttctcgggccagctccaggccacttaacctcagccagctaagcttccaccgc
atccaccaggatgagatcacccagctatcccacttgggccagggcacaaggaccaatgta
tatgagggcctcctgagagtggggggccctgaggagggcaaagcagatggcggagactcc
cccaaacctggagggggctgtgggcagcagctgcgagtagtgcttaaagtactggacccc
agtcaccatgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcc
cacgcacatctggccttcgtgcatggtgtctgtgtgcgcggctccgagaacatcatggtg
acggagtatgtagaaaatgggcccctagacgtgtggctgcggcgagagaagggccatgta
cccatgacctggaaggtggcagtggctcagcagctggccagcgccctcagctacctggag
gacaagaacctggttcatggtaatgtgtgtggccggaacatcctgctggcacggctaggg
ctggcagagggcaccagccccttcatcaagctgagtgatcccggtgtgggcctgggtgcc
ctgtccagggaggagagggtggaacgcatcccctggacggcgcccgagtgcctgcctgct
ggggccaccagtctgtgcactgccgctgacaagtggggctttggtgccactcttctggag
atctgctttgatggggaggcccccctgcagggccgcggtccctctgagaaagagcggttc
taccagaagcagcaccgcctgccagagccctcctgcccagaactggccaccatcaccagc
cagtgcctgacctatgagcgggccctgcgaccttcttttcgcaccatcctgcgtgacctc
actcagctgcagccccacgatctagtggacgtctccactataaatccagactcaccagtg
tcagaccccacggttttccacaagcgatacttgaaaaagatccgggatcttggcgagggt
cactttggcaaggtcagcctgtactgctacgacccgaccaacgatggcacaggtgagatg
gtggccgtgaaagccctcaaggcggactgcgggccccagctccgttctggctggaggcgg
gagatcgatatcctgcgcacgctctaccatgagcatatcgtcaagtacaagggctgctgc
gaggaccaaggcgagaagtcagtgcagctggttatggagtacgtgcccctgggcagcctc
cgagactacctgccccggcacaatgttgggctggctcagctgctgctgttttctcagcag
atctgtgagggcatggcctacctgcacgcgcagcactacatccatcgagatctagctgcc
cgcaacgtgctgctggacaacgacaggctggtcaagattggggactttggcctagccaaa
gccgtgcctgaaggccacgagtactaccgcgtgcgcgaggatggggacagccctgtgttc
tggtatgccccagagtgcctgaaggagtgtaagttctactatgcatctgacgtctggtcc
tttggggtcaccctctatgagctgttgacatactgtgactccagccagagtcccccttcc
aaattcctggagcttataggcctcacccagggacagataactgtgctgaggctcactgag
ttgctggaacgaggggagaggctaccacgacctgagagatgtccctgtgagatctatcat
ctcatgaagaactgctgggaggcagagtcctccttccgccctaccttccagaacctcata
cccatcctcaagatggtccatgagaaataccaaggccaggctccttcagtgttcagcgta
tgctga
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integrated database retrieval system
