Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101967772
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Entry
101967772 CDS
T10664
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti00230
Purine metabolism
iti01100
Metabolic pathways
iti04927
Cortisol synthesis and secretion
iti04934
Cushing syndrome
iti05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101967772 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
101967772 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101967772 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101967772 (Pde8b)
Enzymes [BR:
iti01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
101967772 (Pde8b)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
Motif
Other DBs
NCBI-GeneID:
101967772
NCBI-ProteinID:
XP_005329033
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All DBs
Position
Unknown
AA seq
885 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSEESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRASG
PLGAIRVRRARAELGSGSSAGSAAPAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRSFDAESVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPVTI
NDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQMDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAETEGSDCECNSTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccctagtatccatgtctcgcagagcggcgtgatctactgccgggactcg
gaggagtccaactcgccccgccagaccaccagtgtgtcgcaaggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccattcccccgagccgggcgtcggga
cccctgggcgctatccgcgtccgcagggcccgggctgagctgggcagcggtagcagcgcg
ggctccgcagccccagccgcgaccacctgcaggggccggaggcgtcactgctgcagcagc
gccgaggcggagacccagaccagctacaccagcgtcaagcaggtgtcttctgcggaggta
cgcattgggcccatgagactgacgcaggaccctatccaggttttgctaatctttgcaaag
gaagatagccagagtgatggcttctggtgggcctgtgacagagccggttacagatgcaac
attgctcggactccagagtcagcccttgaatgctttctagataagcatcatgagattatt
gtgattgatcacagacagactcggagctttgatgcggaatcagtgtgcaggtcgatccgg
gccacgaatccctcggagcacacagtgatccttgccgtggtttcacaagcatctgatgac
catgaagaggcctcggtccttcctctcctccatgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaaattacgggcctgtaattcagtgtttacagcattagaccactgtcatgaa
gccatagaaataacaagcgatgaccatgtgattcagtatgtcaacccagcctttgaacga
atgatgggctatcacaaaggggagctcctggggaaggaacttgccgacctgcccaagagt
gataagaaccgtgcagatcttctcgacaccatcaacacgtgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcatgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaagctg
tgttgtaccactgacaataacaagcagattcacaagattcatcgtgattcaggagacaat
tctcagacagaacctcattcattcagatataagaacagaaggaaagagtccattgatgtg
aaatccatatcatctcgaggcagtgatgcaccaagcttgcaaaatcgtcgctatccatcc
atggcaaggatccattccatgaccattgaggctcccatcaccaaggttataaatataatc
aacgcagcccaagaaaacagtccagtcacagtagcagaagccttggacagagttctagaa
attttacggaccacagaattatattcgcctcagctgggtaccaaagatgaagatcctcat
accagtgatcttgttggaggcctaatgacggatggcttgagaaggttgtcaggaaatgag
tacgtgtttacaaagaatgtgcaccagagtcacagtcacctcgcaatgccagtaaccatc
aatgacgttcccccttctattgcccaattacttgataatgaggaaagttgggacttcaac
atctttgaattggaagcggttacacacaaaaggccattggtttacctgggcttaaaggtc
ttctctcgatttggagtatgtgaatttttaaactgttctgaaaccactcttcgggcctgg
ctccaagtgattgaagccaactatcactcctccaatgcctaccacaactccacccatgcc
gccgatgtcctgcatgccaccgctttcttccttggaaaggaaagagtaaagggaagcctg
gaccagatggatgaggtggcagccctgattgctgccacagttcatgacgtggatcacccg
ggaaggaccaactctttcctgtgcaacgcgggcagtgagctcgctgtgctctacaatgac
actgcagtcttggagagtcaccacacagccctggccttccagctcacagtcaaggacacc
aagtgcaacattttcaagaacattgacaggaaccattatcgaacgctgcgccaggctatt
attgacatggttttggcaacagagatgacaaaacactttgaacatgtgaataaatttgtg
aacagcatcaacaagccaatggcagctgagactgagggcagcgactgtgaatgtaactct
actgggaagaactttccagaaaatcaaatcctgatcaagcgcatgatgattaagtgtgct
gatgtggccaacccatgtcgccccttggacctgtgcatcgaatgggccgggaggatctcc
gaggagtattttgcacagacggatgaagagaagagacaggggctaccagtggtgatgcca
gtgtttgaccggaatacctgcagcatccccaagtcccagatctccttcattgactacttc
ataacagatatgtttgatgcgtgggatgcctttgcacatctaccagccctgatgcagcac
ttggcggataactacaaacactggaagacattagatgacctaaagtgcaaaagtctgagg
cttccgtctgacagctaa
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