Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101969299
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Entry
101969299 CDS
T10664
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti04140
Autophagy - animal
iti04141
Protein processing in endoplasmic reticulum
iti04210
Apoptosis
iti04932
Non-alcoholic fatty liver disease
iti05010
Alzheimer disease
iti05012
Parkinson disease
iti05014
Amyotrophic lateral sclerosis
iti05016
Huntington disease
iti05017
Spinocerebellar ataxia
iti05022
Pathways of neurodegeneration - multiple diseases
iti05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101969299 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101969299 (Ern1)
09143 Cell growth and death
04210 Apoptosis
101969299 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101969299 (Ern1)
05012 Parkinson disease
101969299 (Ern1)
05014 Amyotrophic lateral sclerosis
101969299 (Ern1)
05016 Huntington disease
101969299 (Ern1)
05017 Spinocerebellar ataxia
101969299 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
101969299 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101969299 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101969299 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101969299 (Ern1)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101969299 (Ern1)
Protein kinases [BR:
iti01001
]
Serine/threonine kinases: Other
IRE family
101969299 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
101969299
NCBI-ProteinID:
XP_040124525
LinkDB
All DBs
Position
Unknown
AA seq
975 aa
AA seq
DB search
MPARRLLLLLLALLLPGSRIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEDVINLVDQTENAPTTVSQ
DVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQQQLQNQQFQ
KELEKIQLLQQQQLPFHPPGELTQDVELLDTSGPYSESSGTSSPSPSPRASNHSLHSGSS
VSKAGAGPFLEQDEEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLECFHPEKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYYF
HEPLEPQPPVTPDAL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgttgctgctgctgctggcgctgctgttgcccggctccaggatt
tttggaagtaccagcacagtgacactgcctgaaaccttgttgtttgtgtcaacgctggat
ggaagcttgcatgctgtcagcaagaggacaggctccatcaagtggactttaaaagaagac
ccagtcctgcaggtcccgacgcacgttgaagagcctgctttcctcccagatcccaatgat
ggcagcctgtatacacttgggggcaagaataatgaaggcctaacgaaacttccctttacc
atcccagagttggtacaggcatccccatgccgaagttcagatggaatcctctacatgggt
aaaaagcaggacatttggtatgtcatcgacctcttgactggtgagaagcagcagactttg
tcatcggcctttgcagatagtctctgcccatcaacctctcttttgtatcttggacggaca
gaatataccatcaccatgtatgataccaaaacccgtgagctccgctggaatgccacctac
tttgactatgcagcctcactgcccgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatggactcgtggtgactgtggacagcgaatctggggacgtcctgtggatt
caaaactatgcctctccagtggtggccttctatgtctggcagcgggagggtctgaggaag
gtgatgcacatcaatgttgctgtggagaccctacgctacctgaccttcatgtctggggag
gtgggtcgcatcaccaagtggaagtacccgttccccaaagagacggaggccaagagcaaa
ctgacgcctacnctgtatgttgggaagtactccaccagcctctatgcctctccctccatg
gtgcatgagggggtcgctgttgtgcctcgtggcagcactcttcctttgctggaaggcccc
cagactgatggtgtcaccattggggacaaaggggaatgtgtgatcacacccagcacagac
ctcaagtttgaccccggactcaaagggaagaacaagctcaactacttgaggaattactgg
ctcctgataggacaccatgaaaccccgctgtctgcatctaccaagatgctggagaggttt
cccaacaatctacccaaacatcgggaaaatgtgattcctgctgattctgagaaaaagagt
tttgaagacgttatcaacctggtggatcaaacagaaaatgcaccaaccactgtgtctcag
gatgtggaagagaagttggctcgtgcccctgccaagcctgaggctcctgtggactccatg
ctcaaggacatggctaccatcatcctaagcaccttcctgctggttggctgggtagccttc
atcatcacctaccccctgagcatgcatcagcagcagcagctccagaaccagcagttccaa
aaggaactggagaaaatccagctcttgcagcaacagcagctgcccttccatcctcctgga
gaattgacccaggacgtcgagctcctggacacatcaggcccctactcagagagttcaggc
accagcagccccagcccatcccccagggcttcgaaccactcgctgcactctggcagctct
gtctccaaggctggtgccggccccttcctggagcaggatgaggaagatgaggaaaccagc
atggtgattgttgggaaaatttctttctgtcccaaggatgtcctgggccatggagctgag
ggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtgaagaggatcctc
cctgagtgttttagcttcgcagaccgtgaggtccagttgttgcgagaatcagatgagcac
ccgaatgtcatccgttatttctgcacggagagggaccggcagttccaatatattgccatt
gagttgtgtgcagccaccctgcaggagtacgtagagcagaaggactttgcccaccttggc
ctagagcccatcaccttgctgcagcagaccacctcaggcctggcacacctccactccctc
aacattgttcacagagatctgaagccccacaacattctcctctccatgcccaatgcacac
ggcaggatcaaggccatgatctctgactttggcctctgtaagaagctggcggtgggcagg
catagcttcagtcgccgttccggggtgcctggcactgaaggctggattgccccagagatg
ctgagtgaagactgcaaggagaatcctacctatacagtggacatcttctctgcaggctgc
gtcttttactacgtcatctctgagggcagccacccctttggcaagtccctgcagcggcag
gccaacatcctcttgggtgcctacagccttgagtgcttccacccagagaagcatgaagac
gtcattgcacgtgagctgatagagaaaatgatcgccatggatccccagcagcggccctca
gcgaagcatgttctgaaacacccattcttctggagcctggaaaagcagctgcagttcttt
caggacgtgagtgaccgaatagaaaaggagtccctggatggcccgatagtgcgacagtta
gaaagaggcgggagagccgtggtgaagatggactggcgggagaacatcactgtccccctc
cagacagatctgcgtaaattcagaacctacaaaggtggctccgtcagagatctccttcga
gccatgagaaataagaaacaccactaccgggagctcccagtggaggtgcgggagacgctg
ggctcccttcccgatgactttgtgcgctacttcacctcccgcttcccccacctcctctca
cacacctaccgggccatggagctgtgcagccacgagagactcttccagccctactacttc
cacgagcccctggagccccagcccccagtgactccagatgccctctga
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