Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101971244
Help
Entry
101971244 CDS
T10664
Symbol
Braf
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X5
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01521
EGFR tyrosine kinase inhibitor resistance
iti01522
Endocrine resistance
iti04010
MAPK signaling pathway
iti04012
ErbB signaling pathway
iti04015
Rap1 signaling pathway
iti04024
cAMP signaling pathway
iti04062
Chemokine signaling pathway
iti04068
FoxO signaling pathway
iti04150
mTOR signaling pathway
iti04270
Vascular smooth muscle contraction
iti04510
Focal adhesion
iti04650
Natural killer cell mediated cytotoxicity
iti04720
Long-term potentiation
iti04722
Neurotrophin signaling pathway
iti04726
Serotonergic synapse
iti04730
Long-term depression
iti04810
Regulation of actin cytoskeleton
iti04910
Insulin signaling pathway
iti04914
Progesterone-mediated oocyte maturation
iti04928
Parathyroid hormone synthesis, secretion and action
iti04934
Cushing syndrome
iti05010
Alzheimer disease
iti05022
Pathways of neurodegeneration - multiple diseases
iti05034
Alcoholism
iti05160
Hepatitis C
iti05161
Hepatitis B
iti05200
Pathways in cancer
iti05205
Proteoglycans in cancer
iti05208
Chemical carcinogenesis - reactive oxygen species
iti05210
Colorectal cancer
iti05211
Renal cell carcinoma
iti05212
Pancreatic cancer
iti05213
Endometrial cancer
iti05214
Glioma
iti05215
Prostate cancer
iti05216
Thyroid cancer
iti05218
Melanoma
iti05219
Bladder cancer
iti05220
Chronic myeloid leukemia
iti05221
Acute myeloid leukemia
iti05223
Non-small cell lung cancer
iti05224
Breast cancer
iti05225
Hepatocellular carcinoma
iti05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101971244 (Braf)
04012 ErbB signaling pathway
101971244 (Braf)
04015 Rap1 signaling pathway
101971244 (Braf)
04068 FoxO signaling pathway
101971244 (Braf)
04024 cAMP signaling pathway
101971244 (Braf)
04150 mTOR signaling pathway
101971244 (Braf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101971244 (Braf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101971244 (Braf)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101971244 (Braf)
04062 Chemokine signaling pathway
101971244 (Braf)
09152 Endocrine system
04910 Insulin signaling pathway
101971244 (Braf)
04914 Progesterone-mediated oocyte maturation
101971244 (Braf)
04928 Parathyroid hormone synthesis, secretion and action
101971244 (Braf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101971244 (Braf)
09156 Nervous system
04726 Serotonergic synapse
101971244 (Braf)
04720 Long-term potentiation
101971244 (Braf)
04730 Long-term depression
101971244 (Braf)
04722 Neurotrophin signaling pathway
101971244 (Braf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101971244 (Braf)
05205 Proteoglycans in cancer
101971244 (Braf)
05208 Chemical carcinogenesis - reactive oxygen species
101971244 (Braf)
09162 Cancer: specific types
05210 Colorectal cancer
101971244 (Braf)
05212 Pancreatic cancer
101971244 (Braf)
05225 Hepatocellular carcinoma
101971244 (Braf)
05226 Gastric cancer
101971244 (Braf)
05214 Glioma
101971244 (Braf)
05216 Thyroid cancer
101971244 (Braf)
05221 Acute myeloid leukemia
101971244 (Braf)
05220 Chronic myeloid leukemia
101971244 (Braf)
05218 Melanoma
101971244 (Braf)
05211 Renal cell carcinoma
101971244 (Braf)
05219 Bladder cancer
101971244 (Braf)
05215 Prostate cancer
101971244 (Braf)
05213 Endometrial cancer
101971244 (Braf)
05224 Breast cancer
101971244 (Braf)
05223 Non-small cell lung cancer
101971244 (Braf)
09172 Infectious disease: viral
05161 Hepatitis B
101971244 (Braf)
05160 Hepatitis C
101971244 (Braf)
09164 Neurodegenerative disease
05010 Alzheimer disease
101971244 (Braf)
05022 Pathways of neurodegeneration - multiple diseases
101971244 (Braf)
09165 Substance dependence
05034 Alcoholism
101971244 (Braf)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101971244 (Braf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101971244 (Braf)
01522 Endocrine resistance
101971244 (Braf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101971244 (Braf)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101971244 (Braf)
Protein kinases [BR:
iti01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101971244 (Braf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
101971244
NCBI-ProteinID:
XP_005332492
LinkDB
All DBs
Position
Unknown
AA seq
715 aa
AA seq
DB search
MIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYISKLAALQQREQQLLESLGNGTDFSVS
SSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPAR
CGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPL
TTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVS
KFFEHHPIPQEEASLAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADED
HRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTN
VKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVY
KGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWC
EGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKI
GDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTG
QLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA
SIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2148 nt
NT seq
+upstream
nt +downstream
nt
atgattaagttgacacaggaacatatagaggccctactggacaaattcggtggggagcat
aatccaccatcaatatacctggaggcctatgaagaatacatcagcaagctagctgccctc
caacaaagagaacaacagttattggaatccctggggaatggaactgatttttctgtttct
agctctgcatcaatggacaccgttacatcttcttcctcttctagcctttcagtgctacct
tcatctctttcagtttttcaaaaccccacagatgtgtcacggagcaaccccaagtcacca
caaaaacctatcgttagagtcttcctgcccaataaacagaggacagtggtacctgcaagg
tgtggagttacagtacgagacagtctaaagaaagcactgatgatgcgaggtcttatccca
gagtgctgtgctgtttacagaattcaggatggagagaagaaaccaattggctgggacact
gatatttcctggcttacaggggaagaattgcatgtagaagtgttggaaaatgttccactt
acaacacacaactttgtacgaaaaacttttttcactttagcattttgtgacttttgtcga
aagctgcttttccaaggtttccgctgtcaaacatgtggttataaatttcaccagcgttgt
agtacagaggttccactgatgtgtgttaattatgaccaacttgatttgctgtttgtctcc
aagttctttgaacaccacccaataccacaggaggaggcctccttagcagagactgccctt
acatctggatcgtccccttctgcacccccctcagactctattgggccccaaattctcacc
agtccgtctccttcaaaatccattccaattccacagcccttccgaccagcagatgaagat
catcgaaatcaatttgggcaacgagaccgatcctcatctgctcccaatgtgcatataaac
acaatagaacctgtcaatattgatgacttgattagagaccaaggatttcgtggtgatgga
ggatcaaccacaggtttgtctgcaaccccacctgcctcattaccaggctcactcactaat
gtgaaagccttacagaaatctccaggacctcagcgggaaaggaagtcatcttcctcctca
gaagacaggaataggatgaaaacacttggtagacgggattcaagtgatgattgggagatt
cctgatggacagatcacagtgggacaaagaattggatctggatcatttggaacagtctac
aagggaaagtggcatggtgatgtggcagtgaaaatgttgaatgtgacagcacccacacct
caacagttacaggccttcaaaaatgaagtaggagtactcaggaaaacacgacatgtgaat
atcctactcttcatgggctattccacaaagccacaactagctattgttacccagtggtgt
gagggctccagcttatatcaccatctccacatcattgagaccaaatttgaaatgatcaaa
cttatagatattgcacggcaaactgcacagggcatggattacttacacgccaagtcaatc
atccacagagacctcaagagtaataatatatttcttcatgaagacctcacggtaaaaata
ggtgattttggtctagccacagtgaaatctcgatggagtgggtcccatcagtttgaacag
ttgtctggatccattttgtggatggcaccagaagtaatcagaatgcaagataaaaatccg
tacagctttcagtcagatgtatatgcatttgggattgttctgtatgaattgatgactgga
cagttaccttattcaaacatcaacaacagggaccagataattttcatggtgggacgagga
tacctatccccagatctcagtaaggtacggagtaactgtccaaaagccatgaagagatta
atggcagagtgcctcaaaaagaaaagagatgaaagaccactctttccccaaattctcgcc
tctattgagctgctggcccgctcattgccaaaaattcaccgcagtgcatcagaaccctcc
ttgaatcgggctggtttccaaacagaggactttagtctctatgcttgtgcttctccaaaa
acacccatccaggcagggggatatggagaatttgcagccttcaagtag
DBGET
integrated database retrieval system
