Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101975299
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Entry
101975299 CDS
T10664
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101975299 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
iti03032
]
101975299 (Top2a)
03036 Chromosome and associated proteins [BR:
iti03036
]
101975299 (Top2a)
Enzymes [BR:
iti01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101975299 (Top2a)
DNA replication proteins [BR:
iti03032
]
Eukaryotic type
DNA Topoisomerases
101975299 (Top2a)
Chromosome and associated proteins [BR:
iti03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101975299 (Top2a)
Centrosome formation proteins
Centriole proteins
101975299 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101975299
NCBI-ProteinID:
XP_040124738
LinkDB
All DBs
Position
Unknown
AA seq
1534 aa
AA seq
DB search
MEVSPLQPINENMQVNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGIKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYTGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVINGEIAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKEAEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKQRNEKEQELDSLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKAQMTEVLPSPRGKRVIPRVTEEMKAEAEKKIKKKIKSENPEGISKEDGIEPDGLKQ
RLEKKLKKEPGTKAKKQTTLTFKPVKKGKKRNPWSDSESDMSSTESNFDVPPRETEPRRA
AAKTKFTMDLDSDEDFSDFDEKSEDEDFVPSDASPPKTKTSPKHTEKELKPQKDTVSVID
LDDDDDTKDSVPSSSSPPVADLPVETEMKKPSSKKNVTVKKTTTNSQSSTSTTGPKKRAA
PKGTKKDPNLNSDVSQKPEPAKTKNRRKRKPSTSDDSDSNFEKVISKAAASKKPKGESDD
FHLDLDSAVAPRAKSGRAKKPIKYLEESDDDDLF
NT seq
4605 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctataaatgaaaatatgcaagtgaacaaaattaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctaccagaagaaaacgcaattg
gaacatatattgctccgcccagatacttacattggctctgtggaattagtgacccagcaa
atgtgggtttacgatgaagacattggcatgaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcactattgacccagaaaataatttaattagcatatggaat
aatggaaaaggaattcctgttgttgaacacaaagttgaaaaggtgtatgtcccagctctt
atatttggacaactcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattatgtaatatattcagtaccaagtttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacttggatggataacatgggacga
gctggtgagatggagctcaagccttttaatggagaagattatacctgtatcaccttccag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcattgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtctttcttaatggaatt
aagctaccagtaaaaggattccgcagttatgtggatatgtatttgaaggataagttggat
gaaactggcaacccattgaaagtaatacatgaacaagtaaaccacaggtgggaggtgtgc
ctaacaatgagtgaaaaaggctttcagcaaattagtttcgtcaatagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgttgatgta
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaatccaacctttgactctcagaccaaagaaaat
atgactttgcaagccaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccaa
gttcagttaaacaagaaatgttcagctgtaaagcataacagaatcaagggaattccaaaa
cttgatgatgccaatgatgcaggaagtcgaaactccactgagtgtacacttatcctgact
gagggagattcagccaaaactttggctgtttcaggccttggtgttgtagggagagacaag
tatggtgttttccctcttagaggaaaaatactcaatgtccgagaagcttctcataaacag
atcatggaaaatgctgaaattaacaatatcatcaaaattgtgggtcttcagtataagaaa
aactatgaagatgaagattcattaaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggagtttatcactcccattgtaaaggta
tctaaaaacaagcaagaaattgcattctacagccttcctgaatttgaagaatggaaaagt
tctactccaaaccataaaaaatggaaagtcaagtattacaaaggtttgggcaccagtaca
tcaaaagaagctaaggaatactttgcagatatgaaaagacatcgtattcaatttaaatat
actgggcctgaagatgatgctgcaatcagcctggcctttagcaaaaagcagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaagacagcgaaagttacttggcctt
cctgaggattatttgtatgggcaagctaccacttatttgacatataatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaacccggtcaaagaaaggttttatttacttgtttcaaaaggaatgacaaacga
gaggtgaaggttgcccaattagctggatcagtggcagaaatgtcctcataccatcatggt
gagatgtcactaatgatgaccatcatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcaacccattggtcagtttggtacccgcctacatggtggcaaggattct
gctagccctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcatacattgaagttcttatatgatgacaaccaacgagttgagcctgaatgg
tacattcccattatacccatggtcctgataaatggtgctgaaggaattggtactgggtgg
tcctgcaaaattcccaactttgatgttcgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaaaaacttcaaaggtactattgaa
gagctggctccaaatcaatatgtgattaatggcgaaatagctattcttaattccacaacc
attgaaatctcagaacttcccatcagaacatggacccaaacatacaaagaacaagtccta
gaacccatgttgaatggcactgagaagacaccacctctcataacagactacagggaatac
cacacagataccactgtgaagtttgttgtaaagatgactgagggaaaattggcagaggca
gagagagttgggctacacaaagtcttcaaactccaaactagtctcacctgcaactctatg
gtgctttttgatcatgtaggctgtttaaaaaaatatgacacagtgttggatattctaaga
gacttcttcgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaattgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaaaaaagagttaattaaagttctaattcagaga
ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa
gaagagaatgaagagagtgacaatgaaaaggaggcagaaaagagtgactctgtaacagat
tctgggccaaccttcaactaccttcttgacatgcccctttggtatttaaccaaagaaaag
aaagatgaactgtgcaaacaaagaaatgaaaaggagcaagaactggactcattaaagaga
aagagtccatcagatttgtggaaagaagacttagctgcttttattgaggaactggaggct
gttgaagccaaggaaaagcaagatgaacaagtaggactaccagggaaagggggaaaggca
aaggggaaaaaagcacaaatgactgaagttttgccttctccacgaggaaaaagagtcatt
ccccgagttactgaagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaatcctgagggaatctctaaggaagatggtatagaaccagatggcctaaaacaa
agactggagaagaaattgaaaaaagaaccaggcaccaaagcaaagaaacagaccacattg
acgtttaaacctgtcaaaaaaggcaaaaagagaaacccctggtccgattctgaatcagat
atgagcagtactgaaagtaattttgatgtccctccacgagaaacagagccacggagagct
gcagcaaaaaccaaattcacaatggatttggattcagatgaagatttttcagactttgat
gaaaaatctgaagatgaagattttgtgccatcagatgctagcccacctaagaccaaaact
tcaccaaaacatactgaaaaagaactgaagccacagaaagataccgtgtcagtgattgac
ctcgatgatgacgatgatactaaagatagcgtaccatcttcttcgagccctcctgtagct
gatctcccagttgaaactgaaatgaagaagccatcttcaaaaaagaatgtgactgtgaag
aagacaacaacaaatagtcagtcttccacctccactactggtcccaaaaaaagggctgca
ccaaaaggaaccaagaaggatccaaacttgaactctgatgtctctcaaaagcctgaacct
gccaaaaccaagaatcgacgcaaaaggaagccatccacttctgatgattctgacagtaat
tttgagaaagtcatttctaaagcagccgcaagcaagaaacccaagggggagagcgatgac
tttcatctggacttggactcagctgtggctcctcgtgcaaaatctggacgggcaaagaaa
cctataaagtacctcgaagagtcagatgacgatgatttgttttaa
DBGET
integrated database retrieval system
