KEGG   Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101975820
Entry
101975820         CDS       T10664                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
iti  Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti00140  Steroid hormone biosynthesis
iti01100  Metabolic pathways
iti04913  Ovarian steroidogenesis
iti04925  Aldosterone synthesis and secretion
iti04927  Cortisol synthesis and secretion
iti04934  Cushing syndrome
Module
iti_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:iti00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101975820
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101975820
   04925 Aldosterone synthesis and secretion
    101975820
   04927 Cortisol synthesis and secretion
    101975820
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101975820
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:iti00199]
    101975820
Enzymes [BR:iti01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     101975820
Cytochrome P450 [BR:iti00199]
 Cytochrome P450, animal type
  CYP11 family
   101975820
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 101975820
NCBI-ProteinID: XP_005317011
UniProt: I3M915
LinkDB
Position
Unknown
AA seq 519 aa
MLAKGLLQHSVLVKGFQAFLSAAREGVGHPRAPTGIAGISTRSPRPFSEIPSPGDNGWLN
LYHFWRENGAYRIHYHHVQNFQKYGPIYREKLGNVESVYIMDPEDAALIFKSEGPNPERF
LIPPWVAYHQYYRRPMGVLLKKSEDWKKNRVILNQEMMAPEVLKNFVPMLEAVAQDFIGV
LNKRVKQQKSGNFSGDISDDLFRFAFESITNIIFGERLGMLEEIVDPEAQKFIDAIYQMF
HTSVPMLSLPPELFRLFRTKTWRDHAAAWDTIFDKADKYTQNFYWDSRQKRDFSKYPGIL
YSLLGSNKLPFQDIQANITELLAGGVDTTSMTLQWHMYEMARTPKVQEMLRAEVLAARHQ
AQGDINTMLQLVPLLKASIKETLRLHPISVTVQRYLENDLVLRGYIIPAKTLVQVANYAM
GQESSFFTNPGNFNPNRWLDNDKNNTYFRYLGFGWGIRQCLGRRIAELEMTIFLIHVLEN
FKIKIQHLGDVGTKFNLILMPEKPILFTFLPFKQNPVLG
NT seq 1560 nt   +upstreamnt  +downstreamnt
atgctggccaagggacttctccagcattcagtcctggttaaaggttttcaggcattcctg
agcgctgccagggagggtgtgggacatcccagagcacccactggaatagctggtatctcc
acccgcagtcctcgtcccttcagtgagatcccttcccctggtgataatggctggctaaac
ctgtaccatttctggagggagaacggtgcttacagaatccactatcaccatgtccagaat
ttccagaagtatggccccatttacagggagaagcttggcaacgtggagtcagtttatatc
atggaccctgaagatgcggccttgatttttaagtcggagggtcccaacccagaacgattc
cttatccccccctgggtcgcctatcatcagtattaccggaggcccatgggagtcctactg
aagaagtcagaagactggaagaaaaaccgggtgatcctgaaccaggagatgatggctcca
gaggtcctcaagaactttgtacccatgctggaggcggtggctcaagatttcattggtgtc
ctgaacaagcgtgtcaagcagcagaaatctgggaatttctcaggagacatcagtgatgac
ctgttccgctttgcctttgagtccatcaccaacatcatatttggggagcgcctggggatg
ctggaggagattgtggaccccgaggcccagaagttcatcgatgccatctatcagatgttc
cacaccagtgtgcccatgctcagcctacccccagaactgtttcgcctcttcagaaccaag
acctggagggaccatgcggccgcatgggacactatttttgataaagctgacaaatataca
cagaacttctactgggactcgagacagaaaagagacttcagcaaataccctggaatcctg
tatagtctcctgggaagtaacaagctacccttccaggacatccaagccaacattactgag
ctattagcaggaggtgtggacacgacatccatgaccctgcaatggcacatgtacgagatg
gcacgcactccaaaagtgcaggagatgctgagggcagaggttctggctgcccggcaccag
gcccagggagacataaacacaatgctgcagttggtcccactcctcaaagccagcatcaag
gagacactaagactccaccccatctctgtgactgtgcagagatatcttgagaatgacttg
gttcttcgtggctacataattcctgccaagacactggttcaggtggccaattatgccatg
ggccaagaatccagcttctttaccaaccctggaaatttcaacccaaaccgatggctggac
aatgacaagaacaacacctacttccggtaccttggctttggctggggtattcggcagtgt
ctgggccgccggattgcagagctggagatgaccatattcctcattcacgtactggagaac
ttcaaaattaaaatccaacatctcggtgatgtgggtaccaagttcaacctcatcttgatg
cctgagaagcccatcttattcaccttcttgcccttcaaacagaacccagttctgggatga

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