KEGG   Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101976741
Entry
101976741         CDS       T10664                                 
Symbol
Ddb2
Name
(RefSeq) DNA damage-binding protein 2 isoform X2
  KO
K10140  DNA damage-binding protein 2
Organism
iti  Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti03420  Nucleotide excision repair
iti04115  p53 signaling pathway
iti04120  Ubiquitin mediated proteolysis
iti05161  Hepatitis B
iti05169  Epstein-Barr virus infection
iti05200  Pathways in cancer
iti05202  Transcriptional misregulation in cancer
iti05210  Colorectal cancer
iti05212  Pancreatic cancer
iti05213  Endometrial cancer
iti05214  Glioma
iti05216  Thyroid cancer
iti05217  Basal cell carcinoma
iti05218  Melanoma
iti05220  Chronic myeloid leukemia
iti05222  Small cell lung cancer
iti05223  Non-small cell lung cancer
iti05224  Breast cancer
iti05225  Hepatocellular carcinoma
iti05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:iti00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101976741 (Ddb2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    101976741 (Ddb2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    101976741 (Ddb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101976741 (Ddb2)
   05202 Transcriptional misregulation in cancer
    101976741 (Ddb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101976741 (Ddb2)
   05212 Pancreatic cancer
    101976741 (Ddb2)
   05225 Hepatocellular carcinoma
    101976741 (Ddb2)
   05226 Gastric cancer
    101976741 (Ddb2)
   05214 Glioma
    101976741 (Ddb2)
   05216 Thyroid cancer
    101976741 (Ddb2)
   05220 Chronic myeloid leukemia
    101976741 (Ddb2)
   05217 Basal cell carcinoma
    101976741 (Ddb2)
   05218 Melanoma
    101976741 (Ddb2)
   05213 Endometrial cancer
    101976741 (Ddb2)
   05224 Breast cancer
    101976741 (Ddb2)
   05222 Small cell lung cancer
    101976741 (Ddb2)
   05223 Non-small cell lung cancer
    101976741 (Ddb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101976741 (Ddb2)
   05169 Epstein-Barr virus infection
    101976741 (Ddb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:iti04121]
    101976741 (Ddb2)
   03400 DNA repair and recombination proteins [BR:iti03400]
    101976741 (Ddb2)
Ubiquitin system [BR:iti04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     101976741 (Ddb2)
DNA repair and recombination proteins [BR:iti03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      101976741 (Ddb2)
SSDB
Motif
Pfam: WD40 WD40_CDC20-Fz WD40_Prp19 WD40_WDHD1_1st WDR55 Beta-prop_EML_2 Beta-prop_WDR75_1st Beta-prop_RIG_2nd Beta-prop_IFT140_1st Beta-prop_TEP1_2nd ANAPC4_WD40 Beta-prop_WDR90_POC16_2nd Beta-prop_EIPR1 EIF3I Beta-prop_WDR19_1st Beta-prop_TEP1_C WD40_RFWD3 Beta-prop_CAF1B_HIR1 WD40_MABP1-WDR62_2nd NBCH_WD40 WD_LRWD1 Beta-prop_Vps41
Other DBs
NCBI-GeneID: 101976741
NCBI-ProteinID: XP_005330044
UniProt: I3M9Z9
LinkDB
Position
Unknown
AA seq 430 aa
MAPRKRPEAPKTPSVAARLRSKRSPRELEPEAKKLRVKGSGSSRRYDSGCLWAGLASLQV
PPPSSSIVRALHQYKLGKAAWPSLQQGLQQSFLHSLASYRIFQKAAPFDRRATSLAWHPT
HPSTLAVGSKGGDIMLWNFGIKEKPTFIKGIGAGGSITALKFNLLNTNQFFASSMEGTTR
LQDFKGNTLRVFTSSDTCNVWFCSLDVSANSRMVVTGDNVGHVILLNTDGKELWNLRMHK
KKVTHLALNPCCDWLLATASVDQTVKLWDLRQIRGKASFLYSLPHRHPVNSACFSPDGAR
LLTTDQKSEIRIYSASQWDCPLDLIPHPHRHFQHLTPIKATWHPRYNLIVVGRYPDPNFK
SCAPYELRTIDVFDGSSGKMMCQLYDPESSGIISLNEFNPIGDTLASAMGYHILIWSQEE
AKPWDENETH
NT seq 1293 nt   +upstreamnt  +downstreamnt
atggcgcccaggaaacgcccggaagccccgaagacccccagcgtggcggcgcgcctccgg
agcaagagaagtccccgggagctggagcccgaggccaagaagctcagggtgaagggctcc
ggttctagcaggagatatgactcaggctgcctttgggcggggttggctagcctgcaggtc
ccgccaccaagcagcagcatcgtcagggccctccaccagtataagttgggcaaagctgcc
tggccatcactacagcagggtcttcagcagtcctttttgcactctctggcttcttaccgg
atattccaaaaggctgctccctttgacaggagggctacatccttggcatggcacccgact
catcccagcaccctggctgtgggttccaaagggggagatatcatgctctggaactttggc
ataaaggaaaaacccaccttcattaaagggattggagctggagggagcatcactgcgctg
aagtttaaccttctcaataccaaccagttttttgcctcctcaatggagggaacaactagg
ctgcaggactttaaaggcaacactctccgagtttttaccagctcagatacctgcaacgtc
tggttttgcagcctggatgtgtctgccaacagccgaatggtggtcacaggagacaacgtg
gggcatgtgatcctgctgaacacagatggcaaggagctttggaatctccgaatgcacaaa
aagaaagtgacccatctggctctaaacccctgctgcgactggctactggccacagcttcc
gtagatcaaacagtgaaactctgggacctgcgccagattagagggaaagccagcttcctt
tactcgctgccacacaggcatcctgtcaactcagcttgtttcagccctgatggagcccgg
ctcctgaccactgatcagaagagtgagatccggatttactctgcttcccagtgggactgt
cccctggacctgatcccacaccctcaccgtcacttccagcacctaacacccatcaaggca
acctggcatcctcggtacaacctcattgttgtgggccgatacccagatcctaatttcaaa
agttgtgccccctatgaattaaggacgattgatgtgtttgatggaagctctgggaagatg
atgtgtcagctctatgacccagaatcttctggtatcatttcgctcaacgagttcaacccc
ataggggacacgctggcctctgccatgggttatcacattctcatttggagccaggaggag
gctaagccatgggatgaaaatgagacacattga

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