Isoptericola variabilis: Isova_1286
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Entry
Isova_1286 CDS
T01520
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
iva
Isoptericola variabilis
Pathway
iva00300
Lysine biosynthesis
iva00550
Peptidoglycan biosynthesis
iva01100
Metabolic pathways
iva01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
iva00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Isova_1286
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Isova_1286
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Isova_1286
Enzymes [BR:
iva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Isova_1286
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEG44055
UniProt:
F6FSI8
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All DBs
Position
1406636..1408054
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AA seq
472 aa
AA seq
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MIELTAAEVAEATAGRLAGGAAPGTLVTGPVVVDSRQAGAGSLFVALPGEHVDGHDFAAA
ARDAGAVLVLAARELDGVPAVVVDDVQAALGELARHVLARLRATADVKVVAVTGSVGKTT
TKDLLGQLLAPAEGDDPSAVVVPAGSFNNEVGLPLTVLRATPATRRLVLEMGADRPGNIA
YLTRIAPPDVGIVLAVGSAHLGFFGDVETIARTKGEMAEGVVPGGTVALNADDVRVAAMA
ARAPEDAEVVTFGTIPAAAVRATDVEVDAGRARFTLTAGGERAEVALRLVGAHHVTNALA
AATAALRLGVPLGTVAERLSRATALSPHRMAVTERPDGVTVVDDAYNANPDSMKAALRTL
AVMAGRTRRSVAVLGEMRELGDEARVAHDEIGRLVVRLNIKQLVVVGDGAYHIHEGALQE
GSWGEESVFVPDLDAARAVLGETLRPGDVVLVKASNSTGLWRLADELAEVAP
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagctgaccgccgccgaggtcgccgaggcgaccgccgggaggctggccgggggc
gccgcgccggggaccctcgtgaccgggcccgtcgtcgtcgactcgcgtcaggccggggcc
gggtcgttgttcgtcgcgctgccgggcgagcacgtcgacgggcacgacttcgccgcggcc
gcgcgcgacgcgggcgccgtgctcgtgctggccgcgcgcgagctcgacggcgtgcccgcc
gtcgtcgtcgacgacgtgcaggccgcgctcggcgagctcgcgcgccacgtgctcgcacgg
ctgcgggccaccgccgacgtcaaggtcgtggcggtgaccggctcggtcggcaagacgacg
accaaggacctgctcggccagctcctcgcgcccgccgagggcgacgacccgagcgccgtc
gtcgtgcccgccgggtcgttcaacaacgaggtcggcctcccgctgaccgtcctgcgcgcg
acgccggcgacgcgccgcctcgtgctcgagatgggcgcggaccggcccggcaacatcgcc
tacctcacgcgcatcgcgccgcccgacgtcggcatcgtgctcgccgtcggcagcgcccac
ctcgggttcttcggcgacgtcgagaccatcgcccgcacgaagggcgagatggccgagggc
gtcgtgcccggcggcacggtcgcgctcaacgccgacgacgtgcgcgtcgcggcgatggcc
gcgcgcgcccccgaggacgccgaggtcgtcacgttcggcacgatccccgcggccgcggtg
cgcgcgaccgacgtcgaggtcgacgcgggccgtgcccgcttcacgctcacggcgggcggg
gagcgcgccgaggtggcgctgcgcctcgtgggcgcgcaccacgtgaccaacgcgctcgcc
gccgcgaccgccgcgctgcgcctgggggtgccgctcgggacggtcgccgagcggctgtcg
cgggcaaccgcgctgagcccgcaccggatggccgtcaccgagcggcccgacggcgtgacc
gtcgtcgacgacgcctacaacgccaaccccgactcgatgaaggccgcgctgcgcacgctc
gcggtcatggcgggccgcacgcggcggtccgtcgcggtgctcggcgagatgcgcgagctc
ggcgacgaggcgcgcgtggcgcacgacgagatcggccggctcgtggtccgattgaacatc
aagcagctcgtcgtcgtgggcgacggggcgtaccacatccacgagggagcgctccaggag
ggctcctggggggaggagtcggtgttcgtgccggacctcgacgccgcgcgcgccgtcctc
ggcgagacgctgcggcccggcgacgtcgtgctcgtcaaggcgtccaactcgaccggtctg
tggcggctcgcggacgagctcgcggaggtcgccccgtga
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