Isoptericola variabilis: Isova_2224
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Entry
Isova_2224 CDS
T01520
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
iva
Isoptericola variabilis
Pathway
iva00860
Porphyrin metabolism
iva01100
Metabolic pathways
iva01110
Biosynthesis of secondary metabolites
iva01120
Microbial metabolism in diverse environments
iva01240
Biosynthesis of cofactors
Module
iva_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
iva_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
iva00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Isova_2224
Enzymes [BR:
iva01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Isova_2224
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Gene cluster
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Motif
Pfam:
HEM4
Trans_reg_C
Peripla_BP_4
Ribosomal_S11
Motif
Other DBs
NCBI-ProteinID:
AEG44944
UniProt:
F6FQZ4
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Position
complement(2411382..2412539)
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AA seq
385 aa
AA seq
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MSGRWGSGMAEPARPALSQVMAGCTVLITADRRSGELAAALERRGATVRHAPALSMIPHV
DDDALIAATRALVADRPDVVVATTGVGFRAWIEAADAHGLADDLLATLGDARLVARGPKA
RGAIQAAGLQADWVAESETSAEVAEVLLSEGVTGLHVAIQHHGAGADGLDEVFAKAGARV
SSLVVYRWGPAPDPDAVLASVHAAAAGEIDAVAFTSAPGAEAWLEAAEDAGVGPQVVQRF
TSGEMVAAAVGPVTARPLESRGIPTLQPERGRLGALVRALVGHYENVESVALATVAGPLT
IRARVAVLDGHVLPLSPTGVEVLRLLAAAGGDVVPREKVLDVLPGASRDPHAVEVAIARL
REATGRRDLIKTVVKRGYRLELAHD
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
gtgagcggacggtgggggagcggcatggctgagccggcgcgcccggcactcagccaggtc
atggccggctgcaccgtcctcatcaccgccgaccgccgctcgggcgagctcgccgccgcc
ctcgagcgtcgcggcgcgaccgtccggcacgcgccggcgctcagcatgatcccgcacgtc
gacgacgacgcgctcatcgccgcgacgcgcgcgctcgtcgccgaccggcccgacgtcgtc
gtcgcgacgacgggcgtcggcttccgcgcctggatcgaggccgcggacgcgcacgggctc
gccgacgacctgctggcgacgctcggcgacgcgcggctcgtggcacgcggccccaaggcg
cgcggcgccatccaggccgccgggctgcaggcagactgggtcgccgagtccgagacgtcg
gccgaggtggccgaggtgctgctcagcgagggcgtgaccgggctgcacgtcgccatccag
caccacggtgcgggcgcggacgggctcgacgaggtgttcgccaaggcgggcgcgcgcgtc
tcgagcctcgtcgtgtaccggtgggggcccgcgcccgaccccgacgccgtcctcgcgtcg
gtgcacgcggccgccgcgggcgagatcgacgccgtcgcgttcacctccgcgccgggcgcg
gaggcgtggctcgaggccgccgaggacgccggcgtcgggccgcaggtcgtccagcggttc
acgagcggcgagatggtggcggccgccgtcgggcccgtcaccgcacgcccgctcgagtct
cgcggcatcccgacgctccagcccgagcgcgggcgcctcggcgcgctcgtgcgcgcgctc
gtcgggcactacgagaacgtcgagtccgtcgcgctcgcgacggtcgccgggccgctgacc
atccgggcgcgcgtcgccgtgctcgacgggcacgtgctgccgctgtcgcccaccggcgtc
gaggtgctgcgcctgctcgccgcggccggtggcgacgtcgtaccccgggagaaggtcctc
gacgtcctgcccggcgcgtcgcgcgacccgcacgccgtcgaggtcgcgatcgcgcggctg
cgcgaggcgacggggcgccgcgacctcatcaagaccgtcgtcaagcgggggtaccgcctc
gagctcgcgcatgactga
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