Jannaschia sp. CCS1: Jann_2765
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Entry
Jann_2765 CDS
T00330
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
jan
Jannaschia sp. CCS1
Pathway
jan00300
Lysine biosynthesis
jan00550
Peptidoglycan biosynthesis
jan01100
Metabolic pathways
jan01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
jan00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Jann_2765
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Jann_2765
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Jann_2765
Enzymes [BR:
jan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Jann_2765
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABD55682
UniProt:
Q28NN0
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Position
complement(2779944..2781365)
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AA seq
473 aa
AA seq
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MILWTSADAASATGGTSQGTWTATGVSIDTRTIEPGDLFVALAAARDGHEFVAQAFQKGA
SAALVNHVPDGMDAAKCLVVDDVLAALERLGTAARTRTQAKVIAITGSVGKTTVKDMLKQ
ALSGQGKIHAAVASYNNHWGVPLTLSRMPVDTDYAVIEIGMSAPGEIAPLSRMARPHVAM
ITTIAPAHLEAFGRIEGIAEEKASIFEGLEPDGVAIVPMDVETAPILARAAVAHAAEVVT
FGEAEGADLRLTDVMLSDDSTVMRIATDEGGRLAKLSVSGRHYAVNAVGVLCAVAASGAD
TTQAAMALSHWQPVEGRGQRERIQLSRTDDIAIELIDDAFNANPTSLAAGLEVLAAITPE
RGGRRIAVLGDMLELGDDGAKMHADIASLPAMEAVDIVHTCGPLMVHLDAALPGAKRGEH
TETAQDLCRAVPRTLRPGDVVLVKGSKGSRVSLVVDALRKLGQSLERAGQGNR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgattttgtggacttcggcagacgcggcatcggccacgggcggcacaagtcagggcacc
tggaccgcgacgggtgtgtccatcgacacccgcacgattgagccgggcgatctgttcgtg
gccttggccgctgcccgcgacggccatgagttcgttgcccaagcctttcagaagggcgcg
agcgccgcacttgttaaccatgttcccgacggtatggacgccgcgaagtgcctcgttgtg
gacgatgtgcttgccgcgttggagcggcttggaacggcggcccgcacccgcacgcaggcc
aaggtcatcgcgatcacgggctctgtcggcaaaaccaccgtgaaggacatgctgaagcag
gcgctgagcgggcagggtaagatccacgccgccgtcgcctcctacaacaaccattggggc
gtgccgttgacgctgtcgcgtatgcccgttgacacagattatgccgtcatcgagatcggc
atgagtgcccccggcgaaatcgcaccactgtctcgcatggcccggccccacgtggcgatg
atcacgacaatcgcgcccgcgcatctggaggctttcggccgcatcgaaggaattgccgag
gaaaaggcgagtattttcgagggtttggaaccggacggcgtggcgattgtgccaatggac
gtagagacggctccgatcctcgcccgagccgcggtggcacatgcagcagaggttgtgacc
tttggcgaggccgagggcgcggacctgcgcctaaccgatgtgatgctgagcgacgacagc
accgtcatgcggatcgccaccgacgaaggggggcgtttggcgaagctctcggtctctggt
cgccactacgccgtcaatgccgtgggcgttctttgcgccgttgcggcctcgggcgcggat
acgacgcaggcggcgatggcactgtcccattggcaaccggtggagggacgcggccagcgg
gagcgcatccaactgagccggaccgacgacatcgccatcgaactgatcgacgacgctttc
aacgccaacccgacctctctcgcagccggtctggaggtccttgcggcgatcacgccggag
cgcggggggcggcgcatcgccgttttgggcgacatgctggaactgggggatgatggcgcg
aaaatgcacgcagatattgcctcacttcccgcgatggaggcggtggatatcgtccatacc
tgcggtccgctgatggtgcatctcgacgcggctttgcccggtgcaaagcggggggaacac
actgaaacggcgcaagatctgtgccgggcagtgccgcgcaccctgcgtcccggtgacgtt
gtgctggtcaaggggtccaagggctctcgcgtgtcgctggtggttgacgcccttcggaaa
ctggggcaatcgcttgagcgcgcagggcaaggaaaccgctag
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