KEGG   Jannaschia ovalis: P8627_13950
Entry
P8627_13950       CDS       T10628                                 
Symbol
cysG
Name
(GenBank) siroheme synthase CysG
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
jov  Jannaschia ovalis
Pathway
jov00860  Porphyrin metabolism
jov01100  Metabolic pathways
jov01110  Biosynthesis of secondary metabolites
jov01120  Microbial metabolism in diverse environments
jov01240  Biosynthesis of cofactors
Module
jov_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:jov00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    P8627_13950 (cysG)
Enzymes [BR:jov01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     P8627_13950 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     P8627_13950 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     P8627_13950 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Spermine_synth
Other DBs
NCBI-ProteinID: WGH78121
LinkDB
Position
complement(2700410..2701792)
AA seq 460 aa
MNHFPIFLALEGRRVLVSGGGDAAVAKLRLLLKTTARITVVAEDPAPEIAAWAAEGRLTL
IRRAQEPGDALCCVIAYGAHEDAEADGRALRLAAADGAIVNIVDDLARSQFITPAIVDRD
PVVVAIGTEGAAPVLARKIKAELEARLSPATGLLARVAKTFRKTADALPMGAVRRRFWAE
YYDEAGHRAAADGEDAIRATLHELLDTHLKADDRPGHVDLVGAGPGDPELLTLKARNALD
RADVVIHDRLVAPEILELARREATIIEAGKEGFGPAMAQDAINALMVEHARAGAHVVRLK
SGDPTVFGRLDEEIEALDQAGIGWSILPGITAASAAVASIGQSLTKRGRNGAARLLTGHD
MKGFAEQDWAQLARPGEVAAIYMGKRAARWMQGRLMMHGAAPVTPVTLVENASRADQRIR
AATLATLPDAVAEAAGPVVILLGLAPRRAGEAILNREIAL
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaaccatttccccatcttcctcgccctcgagggccgccgcgtcctggtctcgggcggg
ggcgacgcggcggtggcgaagctgcggctgctgctcaagaccacggcgcggatcaccgtc
gtggcggaggatcccgcgcccgagatcgccgcctgggccgccgaagggcgcctgaccctg
atccgccgcgcgcaggagccgggcgacgcgctctgctgcgtgatcgcctatggcgcgcat
gaggatgcggaggccgatggccgcgcgctgcggctggccgcggccgacggggcgatcgtc
aacatcgtcgacgacctcgcccggtcgcaattcattacgcccgccatcgtcgaccgcgat
ccggtcgtggtcgccatcgggaccgagggcgcggctccggttctggcgcgaaagatcaag
gccgagctcgaggcacggctctcgcccgccacgggcctgctggcgcgggtggccaagacc
ttccgcaagaccgccgacgcgcttccgatgggcgccgtccgccgtcgcttctgggccgag
tattacgacgaagccggccaccgtgcggccgccgatggtgaggacgcgatccgcgcaacg
cttcacgagctgctggatacccacctgaaggcagacgaccggcccggccatgtcgacctc
gtcggcgccggccccggtgatccggaactcctgaccctgaaggcgcgcaacgcgctcgac
cgggcggacgtggtgatccacgaccggctggtcgcgcccgagatcctggagctcgcccgc
cgcgaggccacgatcatcgaggccgggaaggaaggcttcgggcccgccatggcgcaggac
gccatcaacgcgctgatggtcgagcatgcccgcgcgggcgcgcatgtcgtccggctgaaa
tccggcgatcccacggtcttcggccgcctcgacgaggagatcgaggcgctggaccaagcg
ggcatcggctggtccattctgccgggcatcaccgccgcctctgccgccgtggcctcgatc
gggcagagcctgacgaagcgcggccgcaacggcgcggcccggctgctgaccggccacgac
atgaagggcttcgccgagcaggactgggcccagctcgcccgcccgggcgaggtcgccgcg
atctacatgggcaagcgcgccgcgcgctggatgcaaggccggctgatgatgcacggcgcc
gcgcccgtgacccccgtcacgctggtcgagaacgcctcgcgcgccgatcagcgcattcgc
gccgccacgctcgccaccctgcccgacgccgtggccgaggccgcgggcccggtcgtcatc
ctgctgggcctcgcgccgcgcagggccggcgaagccatcctcaacagggagatcgcgcta
tga

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