Klebsiella africana: LGL98_21405
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Entry
LGL98_21405 CDS
T07696
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
kar
Klebsiella africana
Pathway
kar00260
Glycine, serine and threonine metabolism
kar00261
Monobactam biosynthesis
kar00270
Cysteine and methionine metabolism
kar00300
Lysine biosynthesis
kar01100
Metabolic pathways
kar01110
Biosynthesis of secondary metabolites
kar01120
Microbial metabolism in diverse environments
kar01230
Biosynthesis of amino acids
Module
kar_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kar_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
kar_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
kar00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LGL98_21405 (thrA)
00270 Cysteine and methionine metabolism
LGL98_21405 (thrA)
00300 Lysine biosynthesis
LGL98_21405 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LGL98_21405 (thrA)
Enzymes [BR:
kar01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LGL98_21405 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LGL98_21405 (thrA)
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Ortholog
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
UDD39716
LinkDB
All DBs
Position
complement(4447722..4450184)
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AA seq
820 aa
AA seq
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MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNIADAERIFAELLQGLADAQPAFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDGVNA
ALICRGEKLSIAIMAGLLEARGHKVSVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRAMEDEFYLELKEGLLEPLAIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQIKRQQGWLKNKHIDLRVCGVANSQALLTSVHGLNLENWSAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELRHFSGILSGSLSFIFGKLDEGVSFSAATAMA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELADIIVESALPPDFDASGNVETFMA
RLPSLDDAFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcggaacggtttctgcgggtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgaccgtcctgtctgccccg
gcgaagatcactaaccacctggtagcgatgattgaaaaaaccattggcggccaggatgcc
ctcccgaatattgccgacgctgaacgcatttttgccgaacttcttcagggccttgccgat
gcccagcccgctttcccacttgcccagctgaaagccttcgttgagcaggaatttgctcag
attaagcatgtcctgcacggcatcagcctgctgggccagtgcccggatggggtgaatgcc
gcgctgatctgccgtggcgaaaagctctctatcgccatcatggcaggtttgctggaagcc
cgtggtcataaagtcagtgtgatcaacccggtagaaaaactgctcgcggtgggccactat
ctggaatccaccgtcgatatcgccgaatccacacgccgcattgccgccagccagatcccg
gcagaccatatgatcctgatggccggatttaccgccggcaatgagaagggcgaactggtg
gtgctggggcgtaatggctccgactattcggctgcggtactggccgcctgcctgcgcgct
gactgctgcgaaatctggaccgatgtcgacggggtgtacacttgcgacccgcgtcaggta
ccggatgcgcgcctgctgaaatcgatgtcttatcaggaggcgatggagctttcctacttt
ggcgcgaaagtgttgcacccgcgcactatcgcgccaatcgcccagtttcagatcccatgc
ctgatcaaaaataccggcaacccgcaggcgccgggaacgcttatcggcgccagccgcgac
gaggacgatctgccggtcaaaggcatctctaacctcaacaacatggcgatgttcaacgtc
tccgggccggggatgaaaggtatggtcggcatggcggcccgcgtcttcgccaccatgtcc
cgcgccggcatctcggtggtgttgatcactcaatcttcttccgagtacagcatcagtttc
tgcgtgccgcagagcgattgcgcgcgtgctaaacgggcgatggaagatgagttttatctg
gagctgaaagaggggttgctggagccgctggccattatggaacgtctggcgatcatctcc
gtggtgggcgacggaatgcgcaccctgcgcggtatctcagcgaaattttttgccgcactg
gcccgcgccaatatcaatattgtggcgattgcccaaggctcttccgagcgctcaatttcg
gtggtggtcagcaatgatgacgccaccaccggcgtgcgcgtgacccatcagatgctgttc
aacaccgaccaggtgattgaagtgtttgtcatcggtgtcggcggcgtcggcggcgcgctg
ctggagcagatcaagcgccagcagggctggctgaagaataaacatatcgatctgcgggtc
tgcggtgtagccaattcgcaggcactgctgaccagcgtgcatggcctgaatctggaaaac
tggagtgcggaactggcggaggcgaaagaaccctttaatcttggccgcctgatccgcctg
gtgaaagagtatcatctgctgaacccggtgatcgtcgactgtacctccagtcaggcggtc
gccgatcagtacgccgacttcctgcgcgaaggtttccatgtggtaacgccgaacaaaaag
gccaacacctcttcgctggattattatcaccagctgcgtcatgcggccagcagctcgcgg
cgtaagttcctctatgacactaacgttggcgccggcctgccggtgattgagaacctgcag
aacctgctcaacgccggcgatgaattgcgccacttctccgggatcctgtccggctccctg
tcgtttatcttcggcaagctggacgagggggtgagtttctccgcggcgacggcgatggcc
cgtgagatggggtataccgagccggatccgcgtgacgatttatccggggtggatgtggcg
cgtaagctgctgattctggcccgtgagaccgggcgagaactggagctggcggacattatc
gtcgagtcggcgctgccgccggacttcgacgccagcggcaatgtcgagacctttatggcc
cgtctgccgtcgctggacgatgcgttcgcctcgcgggttgctaaggcgcgcgatgaaggt
aaagtcttgcgctacgtcggtaacatcgaagaggatgggacctgccgggtaaaaatagcc
gcggttgacggcaacgatccgctgttcaaagttaagaatggtgagaacgcgctggctttt
tatagccattattatcagccattgccgctggtgttacgcggctatggcgccgggaacgac
gtcacggcggccggcgtattcgccgacctgctgcgcaccctgtcctggaagttaggagtt
taa
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