Kitasatospora aureofaciens: B6264_13655
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Entry
B6264_13655 CDS
T05021
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
kau
Kitasatospora aureofaciens
Pathway
kau00860
Porphyrin metabolism
kau01100
Metabolic pathways
kau01110
Biosynthesis of secondary metabolites
kau01120
Microbial metabolism in diverse environments
kau01240
Biosynthesis of cofactors
Module
kau_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
kau_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
kau00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
B6264_13655
Enzymes [BR:
kau01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
B6264_13655
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
B6264_13655
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ARF79809
UniProt:
A0A1E7N664
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Position
3134680..3136326
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AA seq
548 aa
AA seq
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MSPTAATDALFPAGQPTGRCTFLGAGPGDPGLLTLRAVEVLSSADVLVADPLTAAAVRTH
CPAGVQVHSPVAEGSDFDLAKLVAEAVRAGKHVVRTVDGDPGLDGCAAEEMLSCAGDGIP
FEVIPGVAQSVGVPAYAGVPLRGAAGTDVRFVDGAQLLSGAPVDLGAPETTLVVRTTLGQ
LPATANALVSNGRKPDSALSATLSGTTTRQRTFTSTLSTIAADLKAARVLPSPVSAPVDP
ATSVIAVVGEQVAHRASHSWFETKPLFGWNVLVPRTKEQAHGLSEQLRSYGAVPQEVPTI
AVEPPRTPQQMERAIKGLVTGRYEWIAFTSVNAVRAVREKFEEYGLDARAFAGIKVAAVG
ETTAQALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVLLPRADIATETLVAGL
VELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTV
IACIGPATAKTAEEHGLRVDVMAPAPSAAALAQALADFGAKRRDAATAAGEPVYRPSERR
PGSRRKAR
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgagccccaccgccgccaccgacgccctgttcccggccggccagcccaccggacggtgc
accttcctgggggcgggcccgggggacccgggcctgctgaccctgcgcgcggtcgaggtg
ctgtcctcggccgacgtcctggtcgccgacccgctgaccgccgcggccgtacgcacccac
tgcccggccggcgtgcaggtgcactccccggtcgccgagggcagcgacttcgacctggcc
aagctggtcgccgaggccgtccgggccggcaagcacgtggtccgcaccgtcgacggcgat
ccgggcctggacggctgcgccgccgaggagatgctcagctgcgcgggcgacgggatcccc
ttcgaggtgatcccgggcgtcgcccagtcggtcggcgtcccggcgtacgcgggcgtcccg
ctgcgcggcgcggccggcaccgacgtgcgcttcgtggacggcgcccagctgctgtccggt
gccccggtcgacctgggcgcgccggagaccaccctggtggtgcgcaccaccctgggccag
ctgccggccaccgcgaacgcgctggtctccaacggccgcaagccggactcggcgctgagc
gccaccctgtccggcaccaccacccgtcagcgcaccttcacctccacgctgtccaccatc
gcggccgacctcaaggccgcccgggtgctgccctcgccggtgtccgccccggtggacccg
gcgacctcggtgatagccgtggtgggcgagcaggtcgcccaccgggcctcgcactcgtgg
ttcgagaccaagccgctgttcggctggaacgtcctcgtgccgcgcaccaaggagcaggcc
cacggcctgtccgagcagctgcgctcgtacggcgcggtgccgcaggaggtgccgaccatc
gcggtcgagccgccgcgcaccccgcagcagatggagcgggccatcaagggcctggtcacc
ggccggtacgagtggatcgccttcacctcggtgaacgcggtgcgtgccgtccgggagaag
ttcgaggagtacggcctggacgcccgggcgttcgccgggatcaaggtcgcggcggtcggt
gagaccaccgcgcaggcgctggtggacttcggtgtgaagccggacctggtgccctccggc
gagcagtccgcggccgggctgctggaggactggccgccgtacgacccggtcttcgacccg
atcgaccgggtcctgctgccgcgcgccgacatcgccaccgagaccctggtggccggcctg
gtcgagctcggctgggaggtcgacgacgtgacggcgtaccggacggtgcgcgcctcgccg
ccgccggccgagacccgcgaggcgatcaagggcggcggcttcgacgcggtgctgttcacc
tcgtcctcgaccgtccggaacctggtcggcatcgccggcaagccgcacaacgtcacggtc
atcgcctgcatcggcccggccaccgccaagaccgccgaggagcacggcctgcgggtcgac
gtgatggccccggcgccgtcggcggccgcgctggcccaggcgctggcagacttcggagcc
aagcgccgcgacgccgcgacggccgcgggcgagccggtctaccggcccagcgagcgccgt
ccgggatcccgccgcaaggcccgctga
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