Kitasatospora aureofaciens: B6264_19200
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Entry
B6264_19200 CDS
T05021
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kau
Kitasatospora aureofaciens
Pathway
kau00300
Lysine biosynthesis
kau00550
Peptidoglycan biosynthesis
kau01100
Metabolic pathways
kau01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kau00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
B6264_19200
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
B6264_19200
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
B6264_19200
Enzymes [BR:
kau01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
B6264_19200
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NUDIX-like
GGDEF_2
DUF2126
Motif
Other DBs
NCBI-ProteinID:
ARF80750
UniProt:
A0A1E7N4E6
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Position
4361965..4363368
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AA seq
467 aa
AA seq
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MIALTLAEVAAAVGGTLDGADPDTVVTGPVEVDSRKVSPGGLFAAFVGENVDGHDYAATA
VEAGAVAVLASRPVGVPAVLVDSVVEALGRLARTVVARAEGTAVVALTGSAGKTSTKDLI
AQLLRRHGETVFPPGSLNNEIGHPMTALRVEESTRHLVMEMGARHKGDIEYLTSITPPRI
GLVLNVGTAHVGEFGSQEAIAEAKGELVEALPADGAAILNADDRLVRAMASRTKAKVVLF
GESPDAHVRATDVRLDATGRPSFTLTTPAGSAPVQLRLYGEHHVSNALAAAAVATELGMT
VDDTAAALGEAGALSRWRMEVVDRADGVTVVNDAYNANPDSMRAALRALVSMGGRGPERR
RTWAVLGEMRELGEDSLAEHDAIGRLAVRLDVTKLVAVGGREAACMELGARNEGSWGEES
VLVSDADAAVELLRSQLRPGDVVLVKASRSVGLEKVAEALLADGAAR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgaccctcgccgaggtggccgccgccgtcggaggcaccctggacggcgcc
gacccggacaccgtggtcaccggcccggtcgaggtcgactcgcggaaggtgagccccggc
ggcctgttcgcggccttcgtcggcgagaacgtggacggccacgactacgccgccacggcg
gtcgaggccggcgccgtcgcggtgctggcctcccgcccggtcggcgtgcccgccgtcctg
gtcgacagtgtggtggaggcgctcggcaggctggcccggaccgtggtcgcccgcgccgag
ggcaccgccgtggtcgcgctgaccggctcggccggcaagaccagcaccaaggacctgatt
gcccagctgctccggcgccacggcgagaccgtcttcccgcccggctcgttgaacaacgag
atcggccacccgatgaccgcgctgcgggtcgaggagagcacccggcacctggtgatggag
atgggcgcccggcacaagggcgacatcgagtacctcacctcgatcaccccgccgcggatc
ggcctggtgctcaacgtcggcaccgcccacgtcggcgagttcggctcccaggaggcgatc
gccgaggccaagggcgagctggtcgaggcgctgcccgccgacggcgccgcgatcctgaac
gcggacgaccggctggtgcgcgcgatggcctcgcgcaccaaggcgaaggtggtcctgttc
ggggagtccccggacgcccacgtccgggcgaccgacgttcgcctggacgccaccggtcgg
ccgtcgttcacgctcaccaccccggccggttccgcgcccgtgcagctgcgcctgtacggt
gagcaccacgtctcgaacgccctcgccgccgccgcggtggcgacggagctcgggatgacc
gtcgacgacaccgcggcagccctgggcgaggcgggtgcgctgtcccgctggcgcatggag
gtcgtcgaccgggccgatggtgtcaccgtcgtcaacgacgcctacaacgcgaaccccgac
tcgatgcgggccgcgctgcgggcgctggtctcgatgggcggccgcggtccggagcgccgc
cgcacctgggcggtgctcggcgagatgcgggagctcggcgaggacagcctggccgagcac
gacgccatcgggcggctcgccgtccggctggacgtcaccaagctggtggcggtcggcgga
cgcgaggcggcctgcatggaactcggcgcgaggaacgaaggttcgtggggtgaggagtcg
gtgctggtgtccgacgcggacgcggcggtcgaactgctgcgcagtcagcttcggccgggg
gatgtggtcctggtgaaggcgtcccgttcggtggggctggagaaggtggccgaggccctc
ctggcggacggtgctgcccgatga
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