Ktedonosporobacter rubrisoli: EPA93_12140
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Entry
EPA93_12140 CDS
T05969
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kbs
Ktedonosporobacter rubrisoli
Pathway
kbs00300
Lysine biosynthesis
kbs00550
Peptidoglycan biosynthesis
kbs01100
Metabolic pathways
kbs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kbs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EPA93_12140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EPA93_12140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EPA93_12140
Enzymes [BR:
kbs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EPA93_12140
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QBD76713
UniProt:
A0A4P6JNG8
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All DBs
Position
2651305..2652759
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AA seq
484 aa
AA seq
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MFSFEDLLQGNRGHISIVGTTDPAPDLSFRSAQHDSRHCGVGDLYIALKGARVDGHDFIP
DAARAGAIGALCTTPHADVPPGFLQFVVPDVVKAVQATARVRVQRQPETIKIGITGSSGK
TTTKEAIAAILSKVAPTLKTYSSYNNELGYPLTLLSLQAEHRYAVLEMGTERIGELRELC
ETIARPDWSVIITVGAAHLKYFGTRENVAIGKSELVQVLSEEGIALLNYDDQRVRAMNEK
TRARVIYYGRDAQADVRAVELQGLGLFGTHFILCVERQKIPVKLALPGAHGVTTALAAAA
VGHAAGIPLDVIRDGLETLTPFKGRGEVRRGAGPNGSTVIDDTYNSVQESLIIMTQALRE
TPLPATGKRWAVLGEVMEQGDYTLEGHYSVGKALNGTCDYLVAIGDYARYFIQGAQESGM
PAQNIYYFQVDPYQEAEVEEAKRAAVALLKEKVKSDDLVLVKGGHRLHMETMVALLTDQK
GEEE
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgtttagtttcgaggatcttctacagggaaaccggggacatatctctattgtgggcaca
accgatcctgcgccggatctatccttccgtagcgcgcagcacgatagccgccactgcggt
gtgggagatctttatatagcgctgaaaggtgccagagtggatgggcatgactttatccct
gacgcggcacgagccggggccattggcgccctctgtaccacgcctcacgcggacgttcct
ccaggttttcttcaatttgttgtgccagatgtcgtcaaagctgtccaggctaccgcgcgg
gtgagagtgcaacgacagccagaaaccataaaaataggtataactggtagtagtggcaaa
acgacgaccaaggaagctattgcggctatcctgagtaaagttgctccaaccttaaaaact
tactcctcttataacaatgagcttggctatccccttacccttttgagtttgcaagcagag
catcgctatgcagttctggagatgggaaccgagcgtataggagagctacgtgagctttgt
gaaacgattgcgcgccccgattggtctgtcattattactgtcggcgcggctcatttgaaa
tactttggcacacgagaaaacgtcgccattggcaagagcgaacttgtgcaggtgctctca
gaagaaggcatagctttgttgaactatgacgaccagcgggtacgggcgatgaacgagaag
accagagcacgtgtaatctactatggcagagatgcccaggccgatgtgcgcgcggtggag
cttcaagggcttggtctcttcggcacccattttatcctgtgcgttgagcggcagaagatt
ccggtgaaactggcattgccgggcgcacacggagtcaccacggcgctggctgctgcggct
gttggccatgcggcgggtataccgcttgatgtcatacgcgatggattagagacgcttaca
ccgtttaaaggacggggtgaagtcaggcgcggcgcaggtcccaatggtagtacagtcatc
gatgatacttacaattccgtccaggaatcccttattataatgacacaggctctgcgcgaa
acaccgttgccggccactggcaagcgttgggcggttctgggggaagtgatggagcaggga
gactataccttggagggacactattctgtggggaaggctctcaatggcacctgcgactat
ctggtggccattggagactacgcccgctactttatccaaggcgcgcaggagtcgggcatg
ccggcacaaaacatctattactttcaggtcgatccctatcaggaggccgaggtagaggag
gccaaacgcgcagctgttgccctgctcaaggagaaagtgaagtctgatgacctggttctg
gtcaagggtgggcatcgcttgcacatggaaaccatggtagccctcctcacagaccaaaaa
ggagaagaagaatga
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