Streptomyces sp. NL15-2K: Q4V64_37545
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Entry
Q4V64_37545 CDS
T09250
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
kbu
Streptomyces sp. NL15-2K
Pathway
kbu00290
Valine, leucine and isoleucine biosynthesis
kbu00660
C5-Branched dibasic acid metabolism
kbu01100
Metabolic pathways
kbu01110
Biosynthesis of secondary metabolites
kbu01210
2-Oxocarboxylic acid metabolism
kbu01230
Biosynthesis of amino acids
Module
kbu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kbu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Q4V64_37545 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Q4V64_37545 (leuC)
Enzymes [BR:
kbu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Q4V64_37545 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
Q4V64_37545 (leuC)
SSDB
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Paralog
GFIT
Motif
Pfam:
Aconitase
BON_like
DUF4946
Motif
Other DBs
NCBI-ProteinID:
WKX12924
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All DBs
Position
8336944..8338374
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPKTMAITVNGELPDGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLDGRPHAPKGEDWDAAVAYWKTLRTDEDAEFDAEVVIEAAELSPFVTWGTNPGQGAPL
SAHVPDPASYEDASERFAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
IIKDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAETRTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgatcacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggccttcgcaagagcggtcgccgggtgcgtcgactcgacctgaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgcggacccggtctcccgc
gtccagctggagacgctgcgcaagaactgcgccgacttcggtgtgcgcctgcacccgctc
ggtgacgtcgagcagggcgtcgtacacgtcgtcggcccgcagctgggtctgacgcagccg
ggcatgacggtcgtctgcggcgactcgcacacctccacgcacggtgccttcggcggcctg
gccttcggcatcggaacctcccaggtcgagcacgtgctggccacgcagacgctgcccatg
gcccggcccaagaccatggccatcaccgtcaacggcgaactgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaggatcggtacgggcggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctcgatggccgcccgcacgcccccaagggcgaggactgggacgcggccgtcgcc
tactggaagacgctgaggacggacgaggacgccgagttcgacgccgaggtcgtcatcgag
gccgccgaactgtcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcccacgtccccgatcctgcttcgtacgaagacgcttcggagcgcttcgccgccgaa
aaggccctggaatacatggggttggaggccggacagccgctgcgctccatcaaggtggac
accgtcttcgtaggctcgtgcaccaacggccgtatcgaggacctgcgcgctgccgcggag
atcatcaaggaccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctccgcg
cgcgtgggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgttcgatgtgtctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggt
cgtacgcacctggtgtcgccgcaggtcgcggccgctacggcggtgctgggccacctggcc
tccccggccgacctgtccgacgccgagacccgtacgcccgctggagtctga
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