Kitasatospora cathayae: O1G21_27895
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Entry
O1G21_27895 CDS
T10326
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kch Kitasatospora cathayae
Pathway
kch00300
Lysine biosynthesis
kch00550
Peptidoglycan biosynthesis
kch01100
Metabolic pathways
kch01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kch00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
O1G21_27895
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
O1G21_27895
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
O1G21_27895
Enzymes [BR:
kch01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
O1G21_27895
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
WBP89290
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Position
6235855..6237258
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AA seq
467 aa
AA seq
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MIALTLAEVAAAVGGTLDGAAPDTLVTGPVEVDSRKVSPGGLFAAFVGEHVDGHDYAATA
VEAGAVAVLASRPVGVPAVLVDSVVEALGRLARAVVARAEGTAVVALTGSAGKTSTKDLI
AQLLQHRGATVFPPGSLNNEIGHPMTALRVEEGTRHLVMEMGARHKGDIEYLTSITPPRI
GLVLNVGTAHVGEFGSQEAIAEAKGELVEALPADGAAILNADDRLVRAMASRTKAKVVLF
GESPDADVRATDVRLDATGRPSFTLTTPAGSAPVQLRLYGEHHVSNALAAAAVATELGMT
VDDTAAALGEAGALSRWRMEVVDRADGVTVVNDAYNANPDSMRAALRALVSMGGRGPERR
RTWAVLGEMRELGEESLAEHDAIGRLAVRLDVTKLVAVGGREAACMELGARNEGSWGEES
VLVSDADAAVELLRSQLRPGDVVLVKASRSVGLEKVAEALLADGAVR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgaccctcgccgaggtggccgccgctgtcggaggcaccctggacggcgcc
gccccggacaccctggtcaccggcccggtcgaggtcgactcgcggaaggtgagccccggc
ggcctgttcgcggccttcgtcggcgagcacgtggacggccacgactacgccgccacggcg
gtcgaggccggcgccgtcgcggtgctggcctcccgcccggtcggcgtgcccgccgtcctg
gtcgacagtgtggtggaggcgctcggcaggctggcccgggccgtggtcgcccgcgccgag
ggcaccgccgtggtcgcgctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgctccagcaccgcggcgcgaccgtcttcccgcccggctcgctcaacaacgag
atcgggcacccgatgacggcgctgcgggtcgaggagggcacccggcacctggtcatggag
atgggcgcccggcacaagggcgacatcgagtacctcacctcgatcaccccgccgcggatc
ggcctggtgctcaacgtcggcaccgcccacgtcggcgagttcggctcccaggaggcgatc
gccgaggccaagggcgagctggtcgaggcgctgcccgccgacggcgccgcgatcctcaac
gcggacgaccggctggtgcgcgcgatggcctctcgcaccaaggcgaaggtggtcctgttc
ggggagtccccggacgccgacgtccgggcgaccgacgttcgcctggacgccaccggacgg
ccgtcgttcacgctcaccaccccggccggttccgcgcccgtgcagctgcgcctgtacggt
gagcaccacgtctcgaacgccctcgccgccgccgcggtggcgacggagctcgggatgacc
gtcgacgacaccgcggcagccctgggcgaggcgggtgcgctgtcccgctggcgcatggag
gtcgtcgaccgggccgatggtgtcaccgtcgtcaacgacgcctacaacgcgaaccccgac
tcgatgcgggccgcgctgcgggcgctggtctcgatgggcggccgcggtccggagcgccgc
cgcacctgggcggtgctcggcgagatgcgggagctcggcgaggagagcctggccgagcac
gacgccatcgggcggctcgccgtccggctggacgtcaccaagctggtggcggtcggcgga
cgcgaggcggcctgcatggaactcggcgcgaggaacgaaggttcgtggggtgaggagtcg
gtgctggtgtccgacgcggacgcggcggtcgagctgctgcgcagtcagctgcggccgggg
gatgtggtcctggtgaaggcctcccgttcggtggggctggagaaggtggccgaggccctc
ctggcggacggtgctgtccgatga
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