Kluyvera genomosp. 3: CEW81_20630
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Entry
CEW81_20630 CDS
T04930
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kgo
Kluyvera genomosp. 3
Pathway
kgo00300
Lysine biosynthesis
kgo00550
Peptidoglycan biosynthesis
kgo01100
Metabolic pathways
kgo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kgo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CEW81_20630
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CEW81_20630
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CEW81_20630
Enzymes [BR:
kgo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CEW81_20630
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ASG64128
UniProt:
A0A248KKD6
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Position
complement(4104698..4106056)
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AA seq
452 aa
AA seq
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MINVTLKQLTDILRGELHGDDRLIADVTTDTRKLTPGCLFVALKGERFDAHDFAQTAKDG
GAGALLVSRKLDIDLPQLVVADTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTAEHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLPENGIAILNADNNDWANWQQVIGDRTVWRFS
PNAAGSDFSAANVRITSQGTEFTLNTPKGSVDVLLPLPGRHNIANALAATALATAVGADL
SAVKAGLAQLKAVPGRLFPIHLTDSQLLLDDSYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHIQVGEAAKAAGIDRVLSVGKLSQAISTASGEGEHFTEKDSAIARLKSL
INEHKTITILVKGSRSAAMEQVVRAVQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattaacgtcacgttgaagcaactgaccgacattctgcgcggcgaactgcatggcgac
gatcgtctgattgccgatgtcacgaccgacacgcgtaaattaaccccaggttgcctgttt
gtggcgctgaagggtgaacgttttgacgcgcacgactttgcgcaaacagcgaaagatggc
ggcgcgggcgcgctgctggtcagccgcaagctggatatcgacctgccgcagctggtggtc
gccgatacccgcctcgcctttggcgaactggcagcctgggtacgtcagcaggtgccagcg
cgcgtggtggcgctgaccggttcttccggtaaaacctcggttaaagagatgaccgcggcg
attcttagccagtgcggcaacacgctttataccgcgggcaacctaaataatgacatcggc
gtgccgatgacattactgcgtctgacggcagagcatcagtatgcggtgattgaactgggc
gccaaccatcagggcgaaatcgcctggaccgtcagcctgacccgtccggaagcggcgctg
gtgaacaacctggcggctgcgcaccttgagggcttcggctcgctggcaggcgttgcgaaa
gccaagggcgagatttttaccggactgccggaaaacggtatcgcaattctgaacgcggat
aacaacgactgggccaactggcagcaggtgattggcgatcgtaccgtatggcgcttttcg
ccaaatgcggcgggtagcgattttagcgccgcgaacgtgcgcattacctcgcaaggcact
gagttcacgctaaatacgccgaagggcagcgtggatgtgctgctgccgctgccgggccgt
cacaacatcgctaatgcgctggcggcgaccgcgctggcgacggcggtgggcgcagacctg
agtgcggtaaaagccgggctggcgcagttgaaagcggtgccggggcgtctgttcccgatt
cacctgacggatagccagctgctgctggacgactcctacaatgcgaacgtcggttccatg
accgccgcggtgcaggtgctgtctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgagagtgaagcgtgccacatccaggtcggtgaagcagcgaaa
gcggcgggtatcgaccgtgtgctgagcgttggcaaattaagccaggcgattagcacggcg
agcggggaaggggagcacttcaccgagaaagactcggcgattgcgcgtctgaaatcgctt
attaatgaacataaaacgatcaccattctggtgaaaggatcacgcagtgccgccatggaa
caggtcgtacgcgctgtacaggagaacgggacatgttag
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