Kluyvera intermedia: NCTC12125_02950
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Entry
NCTC12125_02950 CDS
T06042
Symbol
murF_1
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kie
Kluyvera intermedia
Pathway
kie00300
Lysine biosynthesis
kie00550
Peptidoglycan biosynthesis
kie01100
Metabolic pathways
kie01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kie00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC12125_02950 (murF_1)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC12125_02950 (murF_1)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC12125_02950 (murF_1)
Enzymes [BR:
kie01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC12125_02950 (murF_1)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
VDZ84811
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Position
1:complement(2699218..2700576)
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AA seq
452 aa
AA seq
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MIGVTLSQLSGVLNAELVGDDLLIEDVTTDTRKITAGCLFVALRGERFDAHDFAQTAKDN
GAGALLVSRKLDINLPQLVVSDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILAQCGNTLYTAGNLNNDIGVPMTLLRLTPEHQFAVIELGANHQGEIAWTVGLTLPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLSESGVAILNADNNDWANWQQIIGDRRVWRFS
PDAADSDFSASDIRITVQGTVFTLHTPNGNTEVLLPLPGRHNIANALAATALATAVGADL
NAVKAGLAQLKAVPGRLFPIQLSETQLLLDDSYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEDCHIQIGAAAKAAGIDRVLSVGTLSQAISAASGAGEHFTEKASAIARLNTL
INEHKTITILVKGSRSAAMEQVVRALQEIGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattggcgtaacgctaagccagctttccggcgtacttaacgctgaacttgtgggtgac
gatctgctgattgaagacgtcaccaccgacacccgtaaaatcactgcgggttgcctgttt
gtggcgctgagaggtgaacgttttgatgcgcacgattttgcgcaaaccgccaaggataac
ggcgcgggcgcgctgttagtcagccgtaagctggatatcaatctgccacaactggtggtc
agcgatacccgtctggctttcggtgaactggcggcctgggttcgtcaacaggttccggca
cgcgttgtggcgctgaccggttcttccggcaaaacgtcggtaaaagagatgaccgccgct
attttggcacagtgcggcaacacgctttataccgcaggcaaccttaataatgacatcggc
gtgccgatgacattactgcgcctgacgccggaacatcagtttgcggtgattgagttaggg
gcaaaccaccagggtgaaattgcctggaccgtggggctgacccttccggaagcggcgctg
gtgaataacctggcggcagcgcatctggaaggttttggctcattagcgggtgttgcgaag
gccaaaggggagattttctccggcctgtcggaaagcggcgttgcgatcctgaatgcggat
aacaacgattgggcaaactggcagcagatcattggcgatcgtcgcgtctggcgcttctcg
ccggatgcggctgacagcgattttagcgcgagcgatatccgtattaccgtacagggcacc
gtcttcacgctgcatacgccgaatggcaacacagaggtacttttgccactgccgggtcgt
cataacatcgctaatgcgctggccgcaaccgcgctggcgacggcggtgggagccgattta
aatgcggtgaaagccggattagcgcagcttaaagcggttccggggcgtttattcccgatt
cagttgtcggaaactcaactgctgttggatgactcctacaacgcgaacgtcggttcaatg
accgcagcggtgcaggtgctgtctgaaatgccgggctaccgcgtgctggttgtcggtgat
atggcagagctgggtgcggaaagtgaagattgtcatattcagatcggtgctgcggcaaaa
gccgcgggtatcgaccgcgtactgagcgttggcacattaagccaggcaatcagtgctgcc
agcggggcaggagagcatttcaccgagaaggcctcggcaattgcacgccttaacacgctg
attaacgaacataaaactatcaccattctggtgaaaggatcacgcagtgccgccatggaa
caggttgtacgcgcattacaggagatcgggacatgttag
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