Kitasatospora sp. NA04385: HUT16_14380
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Entry
HUT16_14380 CDS
T08635
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
kis
Kitasatospora sp. NA04385
Pathway
kis00860
Porphyrin metabolism
kis01100
Metabolic pathways
kis01110
Biosynthesis of secondary metabolites
kis01120
Microbial metabolism in diverse environments
kis01240
Biosynthesis of cofactors
Module
kis_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
kis_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
kis_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
kis00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HUT16_14380
Enzymes [BR:
kis01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HUT16_14380
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HUT16_14380
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QKW20095
UniProt:
A0A7H8KT97
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Position
complement(3271464..3273083)
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AA seq
539 aa
AA seq
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MTAAGFHPPAGRCTFLGAGPGDPGLLTLRAVDVLGTADVLIADPLTAAAVRTHCPSGVQV
IDPADAGRELADLAADAVKAGRHLVRTVDGDPGLDGCAAQEMLRCAKAGVPFEVVPGVAQ
SVGVPAYAGVPLRGGQGADVRFVDAEALLAGQVVDLGAPETTLVVRTTLGQLPATANSLV
AHGRKPDAALSATLSGTTTRQRTFTSTLAAIAADLKAARVLPSPVSAPVDPATSVIAVVG
EQVAHRASHSWFETKPLFGWNVLVPRTKEQAHGLSEQLRSYGAVPQEVPTIAVEPPRTPQ
QMERAIKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVGETTAQALVD
FGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVLLPRADIATETLVAGLVELGWEVDD
VTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATA
KTAEEHGLRVDVMAPAPSASALAQALADFGATRRDAATAAGEPVYRPSERRPGSRRKAR
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccgccggattccacccgcccgcagggcgctgcaccttcctcggcgccggcccc
ggcgaccccggactgctcaccctgcgcgccgtcgacgtgctcggcaccgccgacgtactg
atcgccgacccgctgaccgccgccgcggtccgcacccactgtcccagcggcgtccaggtc
atcgacccggccgacgccggccgggagctcgccgacctggccgccgacgcggtcaaggcc
ggccgccacctggtccgcaccgtcgacggcgaccccggcctggacggctgcgccgcccag
gagatgctgcgctgcgccaaggccggcgtgccgttcgaggtcgtgcccggcgtcgcccag
tcggtgggcgtgcccgcctacgcgggcgtgccgctgcgcggcggccagggcgccgacgtc
cggttcgtggacgccgaggcgctgctggccggccaggtcgtcgacctgggcgcgccggag
accaccctggtcgtgcgcaccaccctgggccagctgcccgcgaccgccaactcgctggtg
gcgcacggccgcaagcccgacgcggcgctctccgcgacgctctccggcaccaccacccgg
cagcgcaccttcacctccacgctggccgccatcgccgccgacctgaaggccgcccgggtg
ctgccctcgccggtctccgccccggtggacccggcgacctcggtgatagccgtggtgggc
gagcaggtcgcccaccgcgcctcgcactcgtggttcgagaccaagccgctgttcggctgg
aacgtcctcgtgccgcgcaccaaggagcaggcccacggcctgtccgagcaactgcgctcg
tacggcgcggtgccgcaggaggtgccgaccatcgcggtcgagccgccgcgcaccccgcag
cagatggagcgggccatcaagggcctggtcaccggccgctacgagtggatcgccttcacc
tcggtcaacgccgtcaaggccgtccgggagaagttcgaggagtacggcctggacgcccgg
gcgttcgccggcatcaaggtcgcggcggtcggcgagaccaccgcgcaggcgctggtcgac
ttcggcgtcaagcccgacctggtgccctccggcgagcagtccgcggccgggctgctggag
gactggccgccgtacgacccggtgttcgacccgatcgaccgggtgctgctgccgcgcgcc
gacatcgccaccgagaccctggtggccggcctggtcgaactcggctgggaggtcgacgac
gtgaccgcgtaccggacggtgcgcgcctcgccgccgccggccgagacccgggaggcgatc
aagggcggcggcttcgacgcggtgctcttcacctcgtcctcgaccgtccgcaacctggtc
ggcatcgccggcaagccgcacaacgtgaccgtcatcgcctgcatcggcccggccaccgcc
aagacggcggaggagcacggcctgcgggtcgacgtgatggccccggccccgtccgcgtcg
gcgctcgcccaggcgctcgccgacttcggggccacccgccgggacgccgccaccgcggcg
ggcgagccggtctaccggccgagcgaacgccgccccggctcgcgccgcaaggcgcgttga
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