Klebsiella sp. CTHL.F3a: K7H21_23980
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Entry
K7H21_23980 CDS
T08882
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
klc
Klebsiella sp. CTHL.F3a
Pathway
klc00260
Glycine, serine and threonine metabolism
klc00261
Monobactam biosynthesis
klc00270
Cysteine and methionine metabolism
klc00300
Lysine biosynthesis
klc01100
Metabolic pathways
klc01110
Biosynthesis of secondary metabolites
klc01120
Microbial metabolism in diverse environments
klc01230
Biosynthesis of amino acids
Module
klc_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
klc_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
klc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
klc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
K7H21_23980 (thrA)
00270 Cysteine and methionine metabolism
K7H21_23980 (thrA)
00300 Lysine biosynthesis
K7H21_23980 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
K7H21_23980 (thrA)
Enzymes [BR:
klc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
K7H21_23980 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
K7H21_23980 (thrA)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QZY79346
LinkDB
All DBs
Position
complement(5125451..5127913)
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LTNIADAERIFTELLQGLADAQPGFPLAPLKAFVEQEFAQIKHVLHGISLLGQCPDSVNA
SLICRGEKLSIAIMAGLLEARGHDVTVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASSD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCVRAKRVMEDEFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGIGGVGGAL
IEQIKRQQSWLKSKHIDLRVCGVANSRALLTNVHGLNLEHWRDELAEAKESFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELLHFSGILSGSLSFIFGKLDEDVSFSEATRLA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVEPVLPAEFDASGDVDSFMA
RLPSLDDEFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgaccgtactatctgccccg
gcgaagatcactaaccatctggttgcgatgatcgaaaaaaccattggcgggcaggatgcg
ctgaccaatatcgccgatgccgaacgcattttcaccgaacttctgcaaggtctcgccgat
gcacaaccgggctttccgcttgcgccgctgaaagcttttgttgagcaggaattcgcgcaa
atcaaacacgtcctgcacggcattagtctgcttgggcagtgcccggatagcgttaatgcg
tcccttatttgccggggagaaaagctctctatcgccattatggcaggcttgctggaagcg
cgcggtcatgacgtcacggtgatcaacccggttgaaaaactgcttgccgttggccattac
ctcgaatccaccgttgatatcgccgagtcgactcggcgtattgccgccagccagatcccg
gctgaccatatggtgctgatggcgggcttcaccgcgggtaacgaaaaaggtgagctggtg
gtgctggggcgtaacggttctgactactcagcagcagtgctggccgcctgcctgcgcgcc
gactgctgcgagatctggaccgacgttgacggtgtttatacctgcgacccgcgtcaggtt
ccggatgcgcgtttgctgaagtcgatgtcctatcaggaagcgatggagctctcctacttc
ggcgctaaagttttgcacccgcgtactattgcccctatcgcccagttccagatcccctgt
ttaatcaaaaacaccggcaatccgcaggcgccgggtacgcttatcggcgccagcagcgat
gaagacgatctgccggtgaaggggatctccaacctcaataatatggcgatgttcaacgtc
tccggtccggggatgaagggcatggttggcatggcggcgcgcgtgttcgccaccatgtcc
cgcgcgggaatctccgttgttcttattacccagtcctcttctgaatacagcatcagcttc
tgcgtgccgcagagcgattgcgttcgggcgaagcgggtgatggaagatgaattttatctg
gagctgaaggaggggctgcttgagccactgtcgataatggagcgcctggcgattatatcc
gttgttggtgacggtatgcgcacgctgcgcggaatttctgcgaagttcttcgctgcgctg
gcccgcgccaatatcaacattgtcgctattgctcagggctcttccgagcgctctatctcc
gttgtcgtcagcaacgatgacgccaccaccggcgtgcgcgtgactcaccagatgctgttc
aataccgatcaggttattgaagtgtttgtcattggcatcggcggcgtcggcggtgcgttg
atcgaacagatcaaacgccagcagagctggctgaagagtaagcatatcgacctgcgcgtt
tgcggcgtggccaactctcgcgccttgctgactaacgtacacggcctgaaccttgaacac
tggcgcgacgagctggcggaagccaaagagtcgttcaatctgggccgactcattcgtctg
gtgaaagagtaccatctgttgaatccggtgattgtcgactgtacctccagccaggccgtg
gccgatcagtacgccgatttcctgcgcgaagggttccacgtggtcacgccgaacaaaaag
gccaatacctcatcgctggattactatcatcagctgcgccacgccgcaagcagctcacgg
cgtaagtttttatacgacaccaacgtcggcgcggggctgccggttatcgaaaacctgcaa
aatttgctgaacgcgggcgatgagctgctgcacttttccggtattctgtctggctcgctg
tcgtttatcttcggcaaacttgatgaggacgtgagcttttctgaggcgaccaggctggcg
cgtgagatgggctataccgaaccggatccgcgcgacgatctttctggcgttgatgtcgcg
cgtaagttgctgatcctcgcgcgtgaaaccgggcgtgagcttgaactgtctgacattatc
gtggaaccggtgctgccggcggagtttgatgccagcggcgatgttgacagctttatggcg
cggttgccttctctggatgatgagtttgcctcgcgggtcgccaaagcgcgcgatgaaggt
aaggtcttgcgctatgtcggtaatatcgaagaggatggcacctgtcgcgttaaaatcgcc
gcggttgatggcaacgatccgctgtttaaagtgaaaaacggcgagaatgcgctggcgttc
tacagccactattaccagccgctgccgctggtgctgcgcggttatggcgcggggaacgat
gtgacggcggctggcgtattcgccgacctgctgcgtaccctgtcatggaagttaggagtt
taa
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