KEGG   Klebsiella sp. M5al: BWI76_22705
Entry
BWI76_22705       CDS       T09148                                 
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
klm  Klebsiella sp. M5al
Pathway
klm00860  Porphyrin metabolism
klm01100  Metabolic pathways
klm01110  Biosynthesis of secondary metabolites
klm01120  Microbial metabolism in diverse environments
klm01240  Biosynthesis of cofactors
Module
klm_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
klm_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:klm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    BWI76_22705
Enzymes [BR:klm01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     BWI76_22705
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     BWI76_22705
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     BWI76_22705
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Shikimate_DH TrkA_N
Other DBs
NCBI-ProteinID: ARI10159
LinkDB
Position
complement(4729909..4731324)
AA seq 471 aa
MEYLPIFAEVKDRPVLVIGGGEIAARKITFLLRAEAKVHIVAETLMPELAEKVEREEIQW
RATVFEEQQLDDVFLVIAATEDDELNQRVYVAANARYRLVNVVDNQALCSFVFPSIVDRS
PLLVAISSSGKAPVLSRILREKIEALLPTNLGRLAETASYWRHHIKTHLKTTAERRRFWE
RVFTGRFASLMLAGNKAEAEKALEDELRQPEKRPGEIILVGAGPGDAGLLTLRGLQALQQ
ADVVFYDNLVTPEVRELVRRDAETICVGKSASGISVPQQEINRLLVDAAKEGKTVIRLKG
GDPFIFGRGGEELQAAAEAGIPFQVVPGVTAAAGATAYAGIPLTHRDYAQSATFITGHFG
AENSPLDWARLAQSGQTLAIYMGSLKAAEISAQLIANGREGDTPVAVISRGTRADQQTKT
GTLQQLESLAKDAPMPALIVVGDVVQLHQQLAWYQHTSSSEAFKASVVNLA
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtggaatacttgccgatatttgccgaagtgaaagacagacctgtgctggtgatcggcggc
ggcgagatagccgcgcgtaagattacgtttttgctgcgcgctgaagcgaaggtgcacatt
gtcgccgaaacgttgatgccggaacttgccgaaaaggtcgagcgcgaggaaattcagtgg
cgggcaaccgtttttgaagagcagcagcttgatgacgtatttctggtgattgccgccacc
gaagatgacgagctgaaccaacgcgtttacgtcgcggcgaacgcgcgttatcggctggtc
aacgtcgtggataatcaagcgctgtgctcgtttgtctttccatcaattgtcgatcgctct
ccgctgctggtggccatctcttccagcggcaaagcgccggtgctgtcgcggattttgcgc
gaaaaaatcgaagccctgctgcccaccaacctggggcggctggctgaaacggcgagctac
tggcgtcaccatattaaaacccatctgaaaaccaccgccgaacgccgccgcttttgggag
cgcgtgtttaccggtcgttttgccagcctgatgctggcgggcaacaaagccgaagcggaa
aaagcgctggaagatgaacttcggcagccggaaaagcgccccggtgaaattattcttgtc
ggagcagggccgggcgatgccggattgctgactctgcgcggcctgcaggcccttcagcag
gcggacgtggtgttttacgacaacctggtcaccccggaggtgcgcgaactggtgcgccgg
gacgcggagacaatctgcgtcggtaaaagcgcctccggcatatccgtaccgcagcaggag
atcaaccgtctgctggtggacgcagcgaaagagggcaaaacggtgattcgcctgaagggc
ggtgacccgtttatttttggccgcggcggcgaagagctgcaggccgcggccgaagcgggc
attccgtttcaggtcgtcccgggcgtgacggcggcggcgggcgcaacggcctatgccgga
attccgttgacgcatcgtgattatgcccagagcgcaacctttattactggccacttcggc
gcggaaaactcgccgctcgactgggcgcggctggcgcaaagcggccagaccctggcgatt
tatatgggcagcctgaaagcggcggaaatcagcgcgcagctgattgccaacggccgcgag
ggcgataccccggtagcggtgatctcgcgcggcacccgcgccgatcagcaaacgaagacc
ggcacattacaacagcttgaaagcctggcgaaagacgccccgatgcccgccctgatcgtg
gtaggagacgtggtgcaattacatcaacagctcgcctggtatcaacacacctcatcctca
gaggcctttaaggcttctgtagtaaatctggcttaa

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