Klebsiella sp. MPUS7: GUC22_22570
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Entry
GUC22_22570 CDS
T10508
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
klp Klebsiella sp. MPUS7
Pathway
klp00300
Lysine biosynthesis
klp00550
Peptidoglycan biosynthesis
klp01100
Metabolic pathways
klp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
klp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GUC22_22570 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GUC22_22570 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GUC22_22570 (murF)
Enzymes [BR:
klp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GUC22_22570 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
YAcAr
Motif
Other DBs
NCBI-ProteinID:
QHI89545
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Position
complement(4832236..4833594)
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AA seq
452 aa
AA seq
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MIRLTLSQLADITRGELHGSDVAIEDVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKAA
GAGALLVSRRLACDLPQVVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPLNGIAIMNADNNDWLNWQSVIGDRKTWRFS
PNAANSDFTATNVHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMAVGATH
EAIKAGLKDLKAVPGRLFPIQLTDSQLLLDDSYNANVGSLTAAVQVLSEMPGYRVLVVGD
MAELGAESQACHRQVGEAAKAAGLDRVLSVGSLSAEISGASGVGEHFNDKALLVTRLQAL
LSEHKIMTILVKGSRSAAMEVVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgcttgactctcagccagcttgccgacattacgcgcggcgagctgcacggcagc
gatgtggcgattgaagacgtcaccactgacacccgtaaggtcacggcaggctgcctgttc
gtggcgctaaaaggcgagcgctttgacgcacatgactttgccgaacaggctaaggctgcc
ggcgcgggcgcattgttggtcagccggcggctggcctgcgatttgccgcaggtggtggtg
aaggatacgcgtctggcgttcggcgaactggccgcgtgggtgcgccagcaggttccggcg
cgcgtggtcgcgctgaccggatcttcaggcaagacctcggtcaaagagatgaccgccgcg
attctgagccagtgcggcaatacgctgtataccgctggcaacctgaacaatgatatcggc
gtgccgatgacgctgctgcgtctcaccaaagaatatgactacgcggttatcgaactaggc
gccaatcaccagggcgaaattgcctggaccgtcagcctgacgcgacctgaagcggcgtta
gtgaataacctggccgccgcgcacctggaaggttttggttccctggaaggcgtggcgaaa
gcgaagggcgaaatttacaccggcctgccgctcaacggcatcgcgattatgaacgccgac
aataatgactggctgaactggcaaagcgtcattggcgatcgtaaaacctggcgcttctcg
ccgaacgccgccaatagcgacttcacggcaaccaacgttcatgtgacttcgcacgggacc
gaatttactctgcaaaccccaaccggcagcgttgatgtgctgctgccgctgccggggcgc
cataacatcgccaacgcgctggccgcagcggcgctttccatggcggtaggcgcgacgcat
gaggcaattaaagcggggctgaaagatctgaaagcggtgccggggcgtttattcccgatt
cagctgaccgatagccagctcctgctggatgattcctataacgctaacgtcggctcgctg
accgccgcggtgcaggtgctatctgagatgccgggctaccgggtgctggtggtcggcgat
atggctgaactcggcgcggaaagccaggcgtgccatcgccaggtgggcgaagcggcaaaa
gcagccgggctcgatcgcgtactgagcgtaggttccttgagcgcggagatcagcggcgcc
agcggcgtcggtgaacactttaacgataaagcgctgctggtaacgcggctgcaagcgctg
ctgtcagaacacaaaattatgaccattttagtgaagggttcacgtagtgccgccatggaa
gtggtagtacgcgcattacaggagaacggaacatgttag
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