Klebsiella huaxiensis: DA718_24375
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Entry
DA718_24375 CDS
T05915
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
klw
Klebsiella huaxiensis
Pathway
klw00260
Glycine, serine and threonine metabolism
klw00261
Monobactam biosynthesis
klw00270
Cysteine and methionine metabolism
klw00300
Lysine biosynthesis
klw01100
Metabolic pathways
klw01110
Biosynthesis of secondary metabolites
klw01120
Microbial metabolism in diverse environments
klw01230
Biosynthesis of amino acids
Module
klw_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
klw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
klw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
klw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
DA718_24375 (thrA)
00270 Cysteine and methionine metabolism
DA718_24375 (thrA)
00300 Lysine biosynthesis
DA718_24375 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
DA718_24375 (thrA)
Enzymes [BR:
klw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
DA718_24375 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
DA718_24375 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QBG10086
LinkDB
All DBs
Position
complement(5113088..5115550)
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LTNIADAERIFAELLQGLAEAQPGFPLAQLKIFVEQEFAQIKHVLHGISLLGQCPDSVNA
SLICRGEKLSIAIMAGLLEARGHHVTVINPVEKLLAVGHYLESTVDIAESTRRIVASQIP
SDHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASLD
EDGLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRVMEEEFYLELKEGQLEPLSIMDRLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIKRQQSWLKSKHIDLRVCGVANSRALLTNVHGLNLEHWRDELAEAKDGFNLGRLIRL
VKEYHLLNPVIVDCTSSQSVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELLHFSGILSGSLSFIFGKLDEGMSFSDATKLA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVEPALSAGFDASGDVESFMA
RLPSLDDEFASRVVKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgagtt
gccgatattctggagagcaatgccaggcaggggcaggtagccaccgtactttctgcccct
gcgaagattactaaccacttggttgcgatgattgagaaaacgatcggtggtcaggatgca
cttaccaatatcgccgatgccgaacgcatttttgccgaacttctgcaggggctcgctgag
gcccagcctggtttcccgcttgctcagctgaaaatttttgttgagcaagagtttgcgcaa
atcaagcatgtgctgcacggtatcagcctgcttgggcagtgcccggatagcgtcaatgct
tcgctaatctgccggggtgaaaagctttctatcgcgattatggccggtctgctggaagcg
cgtggtcatcacgtcacggtcattaacccagtcgaaaaattgctagcagtaggtcactac
cttgagtccacagttgatatcgctgaatcgactcgccgcattgtcgccagtcagatccca
tcagaccatatggtgctgatggccggtttcaccgcgggcaatgaaaagggtgaactggtg
gttctggggcgtaacggttctgactactccgccgcggtactggctgcctgcctgcgtgcc
gactgttgtgaaatctggactgacgtcgatggtgtttatacctgcgaccctcgtcaggtg
ccagatgcgcgcctgctgaagtcgatgtcttatcaggaagcgatggagctttcttatttt
ggtgccaaagttctgcacccgcgcaccattgcgccaatcgcccagttccagatcccctgt
ttaatcaaaaatacgggtaacccgcaggcaccaggcacgcttatcggtgcgagtcttgat
gaagatggtctgccggtgaaggggatctccaatcttaataatatggcgatgttcaacgtc
tccggtccgggcatgaaaggcatggtaggaatggcggcgcgtgtttttgctaccatgtct
cgcgccggaatttctgtcgttttgatcacccaatcctcttcggaatacagcatcagtttc
tgcgtaccgcagagcgactgcgcgcgggcgaagcgggtgatggaagaagagttctatctg
gaactgaaagagggccaactggaaccgctttctattatggaccgtctggcgatcatctct
gttgtcggcgatgggatgcgtactctgcgcggtatctccgccaagttctttgccgcgctg
gcgcgcgccaacatcaatattgtcgcgattgctcagggctcttccgagcgttctatctct
gttgttgtcagcaatgatgatgcaacaaccggcgtgcgcgtgactcaccagatgctgttc
aataccgaccaggttattgaagtgtttgttatcggcgtcggtggtgttggcggcgcgttg
atcgaacagatcaagcgccagcaaagttggctgaagagtaaacatattgatctgcgcgtt
tgcggcgtcgccaattctcgcgctttgctgaccaatgtacacggtctcaatcttgaacac
tggcgcgatgagctggcggaggccaaagatggatttaatttgggtcgacttattcgtttg
gtgaaagagtatcacctgttgaacccggttattgtcgactgtacctccagccagtccgtc
gccgatcagtacgcggatttcttgcgcgaaggctttcacgtggtcacgccgaacaaaaag
gcgaatacctcatcactggattactatcaccaactgcgtcatgccgcgagcagctctcgg
cgtaagttcttatacgataccaacgtcggcgcgggcctaccggtcattgaaaacctgcaa
aatctgctgaatgcgggcgatgagctgctgcacttctccggtattctgtccggctcgttg
tcgtttatcttcggtaagctggatgaaggcatgagtttctctgatgcaacgaaactggcg
cgtgagatgggctacaccgaaccggatccgcgtgatgatctctctggcgttgatgttgcg
cgcaagctgctgatcctggcgcgtgaaaccgggcgtgagctggagctgtctgacattatc
gttgagccagcgctgtcggcaggttttgacgccagcggcgatgttgaaagctttatggca
cgcctaccttctctcgatgatgagtttgcctcacgggtcgttaaagcgcgcgatgaaggt
aaagtcttgcgttatgttggtaacatcgaagaggatggcacctgccgcgtgaaaattgcc
gcggttgacggcaacgatccgctgttcaaagtgaaaaacggcgagaacgcgctggccttt
tacagccactattatcagccgctgccactggtgctgcgcggctatggcgcgggtaacgat
gtaacggcggcgggcgtattcgctgacctgctgcgtaccctgtcatggaagttaggagtt
taa
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