Klebsiella michiganensis RC10: VW41_03475
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Entry
VW41_03475 CDS
T03782
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kmi
Klebsiella michiganensis RC10
Pathway
kmi00300
Lysine biosynthesis
kmi00550
Peptidoglycan biosynthesis
kmi01100
Metabolic pathways
kmi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
VW41_03475 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
VW41_03475 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
VW41_03475 (murF)
Enzymes [BR:
kmi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
VW41_03475 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AJZ88174
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Position
731608..732966
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AA seq
452 aa
AA seq
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MIRVSLKQLASILNGQLHGADADIIDVTTDTRKLTAGCLFVALKGERFDAHDFAADAVQG
GAGALLVNRKLDIDVPQLVVADTRLAFGELGAWVRQQVPTRVVALTGSSGKTSVKEMAAS
ILRQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVGLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLAANGTAILNADNNDWLNWQAIIGDRKTWRFS
PNAAGSDFTATNIHITSHGTEFTLHTPQGDVDVVLPLPGRHNIANALAATALAMAVGATP
EAIKAGLAELKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAAQVLSEMPGYRVMVVGD
MGELGDEAEACHRQVGEAAKAAGIDCVLSVGVLSQTLSDASDVGEHFTDKQAVVARLKAL
IAEHSILTILVKGSRSAAMEEVVRALQEKQAC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatccgcgtctccctgaagcaactggcgtccattctcaatggacagctacatggcgca
gatgctgacattatcgatgtcacaacggatacccgtaagctgacggctggttgcctgttt
gtcgcgctgaaaggcgaacgttttgacgcccatgactttgctgccgatgcggtgcagggc
ggtgcaggcgcgctactggttaaccgtaagctggatattgatgtgccacagctggttgtg
gccgatactcgtcttgcttttggcgagctaggcgcgtgggttcgccagcaggtgcccact
cgcgttgttgccttaacaggctcttccggcaaaacctctgtgaaggaaatggcggcttct
atcctgcggcagtgtggcaatacactctataccgcaggcaatctgaataacgatatcggc
gtgccgatgacgctactgcgtctgaccccagaatatgattatgccgttatcgagctgggg
gcaaaccaccagggcgaaatcgcatggaccgtaggcttaacgcggcccgaagctgcgctg
gtgaataacctggcggccgcgcaccttgaaggctttggctcactggccggcgttgcgaaa
gcgaaaggcgagatctttaccggcctggcggcaaacggtacggcgatccttaacgccgat
aataacgactggctgaactggcaggctatcattggcgatcgcaaaacctggcgcttctca
ccgaatgccgccgggagtgatttcaccgcgacgaatatccatattacctcccacggcact
gaatttacgctgcatacgcctcagggcgatgttgatgtcgttctgccgctgccgggtcgg
cacaatattgctaacgcgctggcggctaccgcgctggcgatggccgtcggcgcaacgccc
gaagccataaaagcggggctcgcggagcttaaagccgtgccaggccgactgttccctatt
caactggcagaaaatcagctgctgctggatgacagctacaacgctaatgtgggctcaatg
accgcggcggcgcaggtgctgtcagaaatgccgggctaccgcgtgatggtggttggcgat
atgggggagctgggtgatgaagctgaagcttgtcatcgtcaggttggcgaagcggcaaaa
gctgcgggcattgactgcgttctgagcgtcggcgtgttaagccagacgctcagtgacgca
tcagacgttggtgaacattttaccgataaacaggccgtggtggcgcgtttgaaagcgctt
attgcggaacactcaattttaaccattttggtgaaaggttcacgtagtgcggccatggaa
gaggtggttcgcgcattacaggagaaacaagcatgctag
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