| Entry |
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| Symbol |
arhgef12a
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| Name |
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
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| KO |
| K07532 | Rho guanine nucleotide exchange factor 12 |
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| Organism |
kmr Kryptolebias marmoratus (mangrove rivulus)
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| Pathway |
| kmr04270 | Vascular smooth muscle contraction |
| kmr04625 | C-type lectin receptor signaling pathway |
| kmr04810 | Regulation of actin cytoskeleton |
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| Brite |
KEGG Orthology (KO) [BR:kmr00001]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
108243522 (arhgef12a)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
108243522 (arhgef12a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
108243522 (arhgef12a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:kmr04131]
108243522 (arhgef12a)
Membrane trafficking [BR:kmr04131]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
108243522 (arhgef12a)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
LG2:13435978..13478349
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| AA seq |
1448 aa
MSDTQSSFTDRFNKKAIRTSSILSKDHPPDKKPKSDKTSPPSNEFDPTEALVVQKSGSSS
VLAEGKPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIK
VNGTLVTHSNHTEVVKLIKSGSYVALTVLGRPPGLPQIPLPEADPETLGISLSSPNSPAS
ERPYSPLNCLSSSLQQWDENGSACNQRADISLKKFSKEQQELQAMKEEYNRNPSPKLLKD
IQEATKHIPQLQGQLFKATGTTQEAVSGGDEDNSSIIETDCVAAPKGENSTDLSWSSTPA
SRMFGPGSPDSQCPKDSSCASPHSTPRNSFNSYHSPEAEDTTDLEPLSPIPVGSPPPSRP
GFQIIGAEDDYFDSDQEQTNGQFNSFNSIEQLKSRPAHLAAFLHHVISQFDPAPVLCYLY
ADLYKQTNSKETRRVFLDFHAFFMDRAANLKVPVPESVSSDLNRRRMELIPEEINRQHVQ
TLQDSLFPDIQKHLEDFRQKRSMGLTVAEVELTRLDQERVRDRVTLERERSYAENILSKI
DDILITTQPTEEEKCTTIQDVIYTYMKHLGVRVKEPRNLEPKRVRISFLPKMKKSMKTDK
EGDEKVEKKPRFNFLAPQRRPSRIESASAGKTQDNRPRPQKQISQPTLGTNEQMETGLRG
SQSSEGSELTHSLSVSTSSSNSIIHSFDTSRDADIGGTPTSGPSKLLNDSIQSDPLGGLS
CPASHLEFYGLDHLQEDDRESDRAHEGTPKAIRRFEGLGAADVQSEDDQGTDSEHDPPNW
QQLVGREVLAGLRPHEIKRQEVINELFYTERAHVRMLKVLDHIFYQKLSKDAILPPADIK
NIFTNLEEVLQLHVSILEQMTAVRKRNESSVIDQIGDDLLSWFSGGEEEKIKRAVGTFCS
NQPFALEIIKTKQKKDSRFTSFIQEAESNRLCRRLQLKDIIPVEMLRLTKYPLLLDNIVK
YTDNAKEKAKVKQAADCCRRILSHVNQALKESEDKQKLEDYQRRLDLSSLKQTDNPMILE
LKNLDLTKKTLIHKGPLSWKVNKDKIIELFTLLLEDVLVLLQKQDERLILKCHSKNLAGA
PDTKHIYSPIIKLSTVLVRSVATDNKAFFVLSMSENGPQIYELMAPTVSDQKTWQSLISK
RADAIKAKPHSVIPLPQTDRERDGVEIISAGASRLSRDPDRTSTGSTQSTDKESSSASRS
ALQSSPIGSNPFEEVKKDDEEEEEGEEEDGDGFVDPELSYQVAEVDREGDLFDVFPSRAE
EALKTLAALKQVLVTQLMSQEAAEQNKRSTGARLLRTTSLRTPTDSRATVMVHNSSEKSS
SKTQDLTQDLGSGDTGFFDSPEDYGCLVLEGYGGTGESSTDDDILASTTGKPLSTSQVCA
ADSGINLRFSSTSQAGSLSTFSRQVLSHLRNLQTNLNYLKEVEAKYNNLISQRPERSITD
TDENKDKR |
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| NT seq |
4347 nt +upstreamnt +downstreamnt
atgagtgacacacagtccagcttcactgacaggtttaacaagaaagcaatcagaaccagc
agcattctcagtaaagaccatccgcctgacaagaaacccaaaagtgataaaacctcacct
ccctccaatgaatttgacccgacagaagctctggtggtgcagaagagtggcagcagcagt
gtgctagcagaggggaagcctgagtcctgtggtctggtccagcgatgtgtaatcatccag
aaagatgaaaacggcttcgggctcacggtcagcggtgacaacccagtgtttgtgcagctg
gtcaaagaagatggggctgcgatgcgggcaggtgttcagacaggagacaggatcattaag
gttaacgggacccttgttacacattctaatcacactgaagttgtgaaacttatcaaatcg
ggctcttatgtggccctcacggttttgggacgccctccaggacttccccagatccctttg
cctgaagcagatcccgagactttgggtattagcctttcctctcccaactctccagcgtca
gaacgcccatacagtcctctgaactgcctttcctcctcactgcaacaatgggatgaaaac
ggcagcgcctgcaaccagagggctgacatctcgctgaagaagttctcaaaagaacagcag
gagctgcaggccatgaaagaggagtacaacaggaacccctcccccaaactactgaaagac
attcaggaagcaacaaaacacattcctcagctgcagggtcagctcttcaaggccactggg
acgacacaggaggctgtttcaggtggggatgaagacaatagtagcataatagagacagat
tgcgtagctgcccctaaaggagaaaacagcacagacctgtcctggagcagcactcctgcg
tctcgcatgtttggacccggttctccagatagccagtgtccaaaagactcctcctgtgca
agcccacacagcacccccaggaacagcttcaactcctaccactccccagaggcagaggat
accaccgacctggagcctctgtctcccatcccagttggcagtcccccgccttctcgcccc
ggctttcaaataataggagctgaagacgactactttgattcagaccaagagcaaacaaac
ggccagtttaacagctttaacagtattgagcagctcaagtctcgtcctgcccacctcgca
gcattcctgcaccatgtcatctcccagttcgaccccgctccagtgctgtgctacctctat
gctgacctctataagcaaactaactccaaagagaccagacgggtgtttttggacttccac
gccttctttatggaccgagcagcaaatttaaaagttcctgttcctgaatcagtttcttct
gatctcaaccgacggcggatggagctgatcccagaggaaataaacagacagcatgttcaa
acactgcaggactctctgttccctgacattcagaaacacctcgaggacttcaggcaaaaa
cgcagcatgggcctgacggtggctgaagttgagctgaccagactggatcaagagagagtc
agagaccgggtcactcttgagcgggaacgctcgtacgccgaaaacatcctcagcaaaata
gatgacatcctgataactactcaacctacagaggaagaaaaatgcactacaatacaggat
gttatctatacgtacatgaagcaccttggtgtgagggtcaaggaacctcgaaatctggaa
cccaaacgtgttcggatcagctttcttcctaagatgaagaaaagcatgaagacagataag
gagggagatgagaaagtagagaaaaaacccagatttaattttcttgcacctcagcgtcgg
cccagccgcattgaatcagcatcagcgggtaaaacccaggacaatcgccccaggccacag
aaacagatctctcagcccacactggggacaaacgaacaaatggaaactggtctaagaggc
agccaatccagcgaaggctcggaactcacccactccctgtccgtcagcacctcgtcttca
aacagcatcatccacagcttcgacacaagccgagatgctgatatcggtgggacaccaaca
tcaggcccctccaagctgctgaatgacagcattcagtctgaccctctaggtgggttgtca
tgtcctgcttcgcacttggagttttatggtctggaccatcttcaggaggatgacagagaa
agtgacagagctcacgagggaacaccaaaggccatcagaagatttgagggactgggtgct
gctgatgttcagagtgaggacgatcagggtaccgactctgagcacgatccgccgaactgg
cagcagttggtggggcgagaagtcctggcaggtctcaggcctcacgagatcaagagacaa
gaagttatcaatgagctgttttacacggagcgtgcgcatgtacgcatgctcaaggttttg
gaccacattttctaccagaagctttccaaagatgccatccttcctcctgctgacatcaag
aacatcttcaccaacctggaggaggtcttacagctgcacgtttcaattcttgagcaaatg
acggccgttcgtaagagaaacgagtcgtcagtaattgatcaaataggagacgacttgctc
tcctggttcagcggcggggaggaggagaagatcaagcgagcagtggggacgttttgcagc
aaccagccttttgctctggagatcatcaagaccaagcagaagaaagactccaggtttacg
tcattcattcaggaggcagagagtaacaggctgtgtcgccgactgcagcttaaagacatc
attcctgtagagatgctgcggctcaccaaatatccgttgctgctggacaacattgtcaag
tacacagataacgccaaggagaaggctaaagtaaagcaggcggcagactgctgtagaagg
atcctcagtcatgttaaccaggctttgaaagagtccgaggacaagcagaaattagaagac
tatcagagaagattggacctctcctcactgaagcagacagataaccccatgatcctggag
ctaaagaacctggatctaaccaagaagacgttgattcacaagggtccgctgtcatggaaa
gtgaacaaagacaagattattgagctgttcacgctcctcttggaggacgttctcgttctg
ctacagaaacaagatgaacgtctaatccttaagtgccacagcaaaaacctggcaggcgcc
ccagacaccaagcatatctacagccccatcatcaagctcagcactgttctagtgcgttct
gtggctacagacaacaaggccttctttgtgctctccatgtcagaaaacggtccccagatc
tacgagctcatggcgcccacagtctcagatcagaaaacgtggcaaagtctgatctccaag
agagctgatgcaataaaagccaaacctcacagcgtcataccattacctcagactgacagg
gagagagatggagtggagatcatatcagcaggtgcttccagactgagtagagacccggac
cgcacgtccaccggcagcactcagtccacagataaagagagcagctcagcttctagaagt
gcattgcagagttcgccgattggtagtaatccatttgaagaggtgaagaaagatgacgag
gaggaggaggagggggaggaggaggacggggatggctttgtggacccagagctttcttat
caagtggctgaagtcgacagagaaggagacttgtttgatgtgtttccctcgagagcagag
gaagcactaaaaacactggcagcattgaagcaggttttagtgacccagctgatgtcccag
gaggccgcagagcaaaacaaacgctccactggagcccgtctcctcaggaccacctctctg
cggaccccaacagacagccgcgcaacggtgatggtccacaacagctcggagaaaagcagt
tcaaaaacacaggacctgacccaggatctgggatcgggagacactggattctttgactca
cctgaggactacggatgcttagtcctggagggctacggtggcaccggggagagcagcaca
gatgatgacatcttggcatcaaccactgggaagccgctgagcacctcacaagtctgtgct
gccgactctggcatcaatttgcggttttcctcaacgtcacaggccggcagcctctccact
ttcagcagacaggtgctgtctcaccttcgaaatcttcagaccaacctcaactacctgaag
gaggttgaggctaagtacaataatttaataagccaaaggccagagaggtcaataacagac
acggatgaaaacaaagataagagatag |
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