KEGG   PATHWAY: ko00531
Entry
ko00531                     Pathway                                
Name
Glycosaminoglycan degradation
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
ko00531  Glycosaminoglycan degradation
ko00531

Module
M00076  Dermatan sulfate degradation [PATH:ko00531]
M00077  Chondroitin sulfate degradation [PATH:ko00531]
M00078  Heparan sulfate degradation [PATH:ko00531]
M00079  Keratan sulfate degradation [PATH:ko00531]
Other DBs
GO: 0006027
Orthology
K01132  GALNS; N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]
K01135  ARSB; arylsulfatase B [EC:3.1.6.12]
K01136  IDS; iduronate 2-sulfatase [EC:3.1.6.13]
K01137  GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]
K01195  uidA, GUSB; beta-glucuronidase [EC:3.2.1.31]
K01197  hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01205  NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50]
K01207  nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
K01217  IDUA; L-iduronidase [EC:3.2.1.76]
K01565  SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
K07964  HPSE; heparanase [EC:3.2.1.166]
K07965  HPSE2; heparanase 2 [EC:3.2.1.-]
K10532  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78]
K12309  GLB1, ELNR1; beta-galactosidase [EC:3.2.1.23]
K12373  HEXA_B; hexosaminidase [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526  
G00711  
G00872  DWA-2
G01391  
G01945  
G01977  
G02632  
G09660  
G10008  
G10505  Hyaluronic acid
G12336  
G13034  
G13035  
G13036  
G13037  
G13038  
G13039  
G13040  
G13041  
G13042  
G13043  
G13073  
G13074  
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
ko00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
ko00533  Glycosaminoglycan biosynthesis - keratan sulfate
ko00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin

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