KEGG ORTHOLOGY: K14985

KEGG

ORTHOLOGY: K14985

Entry

K14985                      KO

Symbol

CYP18A1

Name

26-hydroxylase [EC:1.14.-.-]

Pathway

Insect hormone biosynthesis

Reaction

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00981 Insect hormone biosynthesis
    K14985  CYP18A1; 26-hydroxylase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K14985  CYP18A1; 26-hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
  CYP18 family
   K14985  CYP18A1; 26-hydroxylase

Genes

BBEL:

AJJ:	139954979 139964920

ARUN:

AAMU:

139951648 139953229 139953230

PFLL:

DME:	Dmel_CG6816(Cyp18a1)

DER:

DSE:

DSI:	Dsimw501_GD24470(Dsim_GD24470)

DYA:	Dyak_GE15501

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10931

DAZ:

DNV:

DHE:

DVI:	6631344(Cyp18a1)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

ECOE:

CLON:

HIS:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

109411507 115264182

ASUA:

CQU:	CpipJ_CPIJ001038

CPII:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139108882(Cyp18a1)

TLN:	139813110(Cyp18a1)

HST:

DQU:

CFO:

FEX:

PMEC:

138942001(Cyp18a1)

LHU:	105675524(Cyp18a1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124217004(Cyp18a1)

NFB:

NLO:

NVG:

AROA:

105690914 105690922

TCA:	656794(Cyp18a1)

TMOL:

138125300(Cyp18a1)

DPA:

ESIM:

136408817(Cyp18a1)

EFOR:

136346416(Cyp18a1)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

108739862 112905471

PPYR:

OTU:

BMOR:

100036578(Cyp18a1) 101740852

BMAN:

114251016 114251017

MSEX:

115443463 115443488

DPL:	KGM_213007

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

106718481 106718533

PPOT:

106109075 106109439

PXU:	106128278 106128479

BPHI:

PRAP:

110994642 110994648

PBX:	123710697 123711250

PNAP:

125052929 125053355

ZCE:	119835033 119835102

CCRC:

123690889 123690891

LSIN:

126966498 126966503

AAGE:

HAW:	110375691 110375713

HZE:	124631430 124631499

TNL:

SLIU:

111351790 111351850

OFU:

ONU:

ATRA:

GMW:

PXY:	105382420 105382421

PGW:

LGLY:

125228140 125228223

CSTB:

134742151 134742462

CFEL:

113370893 113372085

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

126842871 126842904

DVT:	126903337 126903338

BTAB:

DCI:

CLEC:

HHAL:

106686813(Cyp18a1)

NLU:

HVI:	124367320 124367321

MQU:

PHU:	Phum_PHUM319540

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

HAMR:

139696110(Cyp18a1)

FCD:	110847368 110858776

DPX:	DAPPUDRAFT_314153

DMK:

DPZ:

AFRA:

PVM:	113808686(Cyp18a1)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123750307(Cyp18a1)

CQD:	128685393(Cyp18a1)

PTRU:

ESN:

MNZ:

MRJ:

PORN:

139757590(Cyp18a1)

HAZT:

EAF:

LSM:	121116984 121127501

TCF:	131887037 131891121

DSV:

RSAN:

119390570 119390596

RMP:

DFR:

CVS:	136970544(Cyp18a1) 136980940 136986924

ABRU:

129958740 129971105 129971260 129971261 129972878 129973318

UDV:	129222632 129224873 129232769 129234544

SDM:

LPOL:

106461544 106468054

PMEO:

129580916 129581151 129597226

LSAX:

138961775 138961870 138983836

AIRR:

LLON:

Reference

Authors

Bassett MH, McCarthy JL, Waterman MR, Sliter TJ

Title

Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila.

Journal

Mol Cell Endocrinol 131:39-49 (1997)
DOI:10.1016/S0303-7207(97)00093-2

Sequence

[dme:Dmel_CG6816]

Reference

Authors

Guittard E, Blais C, Maria A, Parvy JP, Pasricha S, Lumb C, Lafont R, Daborn PJ, Dauphin-Villemant C

Title

CYP18A1, a key enzyme of Drosophila steroid hormone inactivation, is essential for metamorphosis.

Journal

Dev Biol 349:35-45 (2011)
DOI:10.1016/j.ydbio.2010.09.023

LinkDB

DBGET integrated database retrieval system