KEGG   ORTHOLOGY: K15812
Entry
K15812                      KO                                     
Symbol
CPQ
Name
cucurbitadienol synthase [EC:5.4.99.33]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map00996  Biosynthesis of various alkaloids
map01110  Biosynthesis of secondary metabolites
Reaction
R09688  (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K15812  CPQ; cucurbitadienol synthase
  09110 Biosynthesis of other secondary metabolites
   00996 Biosynthesis of various alkaloids
    K15812  CPQ; cucurbitadienol synthase
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.33  cucurbitadienol synthase
     K15812  CPQ; cucurbitadienol synthase
Other DBs
GO: 0034076
Genes
CSV: 101204533
CMO: 103498907
BHJ: 120068021
MCHA: 111017486
CMAX: 111488502
CMOS: 111455830
CPEP: 111807422
AG: BAD34645(CPQ)
Reference
  Authors
Shibuya M, Adachi S, Ebizuka Y
  Title
Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis.
  Journal
Tetrahedron 60:6995–7003 (2004)
DOI:10.1016/j.tet.2004.04.088
  Sequence
Reference
  Authors
Abe I
  Title
Enzymatic synthesis of cyclic triterpenes.
  Journal
Nat Prod Rep 24:1311-31 (2007)
DOI:10.1039/b616857b
LinkDB

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