KEGG ORTHOLOGY: K17620

ORTHOLOGY: K17620

Entry

K17620                      KO

Symbol

EYA2

Name

eyes absent homolog 2 [EC:3.1.3.48]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17620  EYA2; eyes absent homolog 2
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K17620  EYA2; eyes absent homolog 2
Protein phosphatases and associated proteins [BR:ko01009]
HAD phosphatases
  EYAs
   K17620  EYA2; eyes absent homolog 2

Other DBs

GO:

0004725

Genes

HSA:	2139(EYA2)

PTR:	458305(EYA2)

PPS:	100979089(EYA2)

GGO:	101132212(EYA2)

PON:	103888815(EYA2)

PPYG:

129021876(EYA2)

NLE:	100599613(EYA2)

HMH:	116461107(EYA2)

SSYN:

129474805(EYA2)

MCC:	716182(EYA2)

MCF:	102133126(EYA2)

MTHB:

126929090

MNI:	105496488(EYA2)

CSAB:

103244839(EYA2)

CATY:

105588520(EYA2)

PANU:

101026119(EYA2)

TGE:	112633589(EYA2)

MLEU:

105542279(EYA2)

RRO:	104678799(EYA2)

RBB:

108533310

TFN:	117068877(EYA2)

PTEH:

111526662(EYA2)

CANG:

105502393(EYA2)

CJC:	100388321(EYA2)

SBQ:	101041569(EYA2)

CIMI:

108313065(EYA2)

ANAN:

105727488(EYA2)

CSYR:

103263511(EYA2)

MMUR:

105859292(EYA2)

LCAT:

123622294(EYA2)

PCOQ:

105825807(EYA2)

OGA:	100946496(EYA2)

MMU:	14049(Eya2)

MCAL:

110283740(Eya2)

MPAH:

110318177(Eya2)

RNO:	156826(Eya2)

MCOC:

116091400(Eya2)

ANU:	117704393(Eya2)

ASYL:

127686263(Eya2)

MUN:	110549191(Eya2)

CGE:	100768991(Eya2)

MAUA:

101842200(Eya2)

PROB:

127223553(Eya2)

PLEU:

114692645(Eya2)

MORG:

121460194(Eya2)

MFOT:

126507075

AAMP:

119814716(Eya2)

NGI:	103729381(Eya2)

HGL:	101711844(Eya2)

CPOC:

100731548(Eya2)

CCAN:

109686581(Eya2)

DORD:

105981544(Eya2)

DSP:	122120306(Eya2)

PLOP:

125353865(Eya2)

NCAR:

124977792

MMMA:

125619205(Eya2)

ITI:	101955196(Eya2)

OCU:

100355981

OPI:	101523930(EYA2)

TUP:	102495649(EYA2)

GVR:	103590332(EYA2)

CFA:	609926(EYA2)

CLUD:

112674074(EYA2)

VVP:	112931871(EYA2)

VLG:	121478439(EYA2)

NPO:	129497509(EYA2)

AML:	100482877(EYA2)

UMR:	103669848(EYA2)

UAH:	113258681(EYA2)

UAR:	123797052(EYA2)

ELK:

111141593

LLV:

125109599

MPUF:

101670492(EYA2)

MNP:	132021996(EYA2)

MLK:	131807519(EYA2)

NVS:	122916007(EYA2)

ORO:	101384169(EYA2)

EJU:	114223199(EYA2)

ZCA:	113937565(EYA2)

MLX:

118011063

NSU:	110579421(EYA2)

FCA:	101083833(EYA2)

PYU:	121012077(EYA2)

PCOO:

112869127(EYA2)

PBG:	122467307(EYA2)

PVIV:

125162178(EYA2)

LRUF:

124503759

LGF:	123580072(EYA2)

AJU:

106969019

PTG:	102949178(EYA2)

PPAD:

109272319(EYA2)

PUC:

125936071

PLEZ:

122215458(EYA2)

HHV:	120243270(EYA2)

BTA:	615264(EYA2)

BOM:	102268407(EYA2)

BIU:	109567720(EYA2)

BBUB:

102408490(EYA2)

BBIS:

104985057(EYA2)

CHX:	102170160(EYA2)

OAS:	101118806(EYA2)

BTAX:

128058366(EYA2)

CSUM:

138091346(EYA2)

ODA:	120869114(EYA2)

CCAD:

122448211(EYA2)

MREE:

136158037(EYA2)

OVR:	110133357(EYA2)

MBEZ:

129564471(EYA2)

SSC:	100624872(EYA2)

CFR:	102513361(EYA2)

CBAI:

105071874(EYA2)

CDK:	105087854(EYA2)

VPC:	102546048(EYA2)

BACU:

103009534

BMUS:

118882061(EYA2)

LVE:	103075393(EYA2)

OOR:	101282577(EYA2)

LALB:

132505699(EYA2)

DLE:	111170143(EYA2)

PCAD:

102985174(EYA2)

PSIU:

116740817(EYA2)

NASI:

112400892(EYA2)

ECB:	100071250(EYA2)

EPZ:	103567705(EYA2)

EAI:	106847627(EYA2)

MYB:	102240201(EYA2)

MYD:	102761538(EYA2)

MMYO:

118663782(EYA2)

MLF:	102436058(EYA2)

MDT:	132239863(EYA2)

MYUM:

139014640(EYA2)

PKL:	118708116(EYA2)

EFUS:

103302061(EYA2)

MNA:	107530887(EYA2)

DRO:	112304079(EYA2)

SHON:

118985568(EYA2)

AJM:	119063366(EYA2)

PDIC:

114506419(EYA2)

PHAS:

123814868(EYA2)

MMF:	118618333(EYA2)

PPAM:

129070640(EYA2)

HAI:

109379909

RFQ:	117016179(EYA2)

PALE:

102883767(EYA2)

PGIG:

120603757(EYA2)

PVP:	105298246(EYA2)

RAY:	107498283(EYA2)

MJV:	108401489(EYA2)

TOD:	119236150(EYA2)

SARA:

101549499(EYA2)

SFUM:

130017700(EYA2)

SETR:

126018362(EYA2)

LAV:	100666179(EYA2)

TMU:

101346879

ETF:	101659879(EYA2)

DNM:	101447350(EYA2)

MDO:	100023574(EYA2)

GAS:	123237122(EYA2)

SHR:	100927047(EYA2)

AFZ:

127548882

PCW:	110206618(EYA2)

TVP:	118844894(EYA2)

PBRV:

138149371(EYA2)

OAA:	100074653(EYA2)

TACU:

119931486(EYA2)

GGA:	395745(EYA2)

PCOC:

116227387(EYA2)

MGP:	100539991(EYA2)

CJO:	107322959(EYA2)

TPAI:

128080814(EYA2)

LMUT:

125701292(EYA2)

NMEL:

110408454(EYA2)

APLA:

101799599(EYA2)

ACYG:

106041228(EYA2)

CATA:

118249007(EYA2)

AFUL:

116495924(EYA2)

TGU:	100218165(EYA2)

LSR:	110476166(EYA2)

SCAN:

103818635(EYA2)

PMOA:

120497857(EYA2)

OTC:	121343787(EYA2)

PRUF:

121359699(EYA2)

ATRC:

139599552(EYA2)

GFR:	102040443(EYA2)

FAB:	101816401(EYA2)

OMA:	130261317(EYA2)

PHI:	102110456(EYA2)

PMAJ:

107213431(EYA2)

CCAE:

111938199(EYA2)

CCW:	104687739(EYA2)

CBRC:

103615829(EYA2)

ACOE:

138120873(EYA2)

ETL:	114063048(EYA2)

ZAB:	102075025(EYA2)

ZLE:	135456359(EYA2)

ACHL:

103804417(EYA2)

SVG:	106860867(EYA2)

MMEA:

130573494(EYA2)

HRT:	120760009(EYA2)

SATI:

136368437(EYA2)

CCIC:

134051489(EYA2)

FPG:	101921391(EYA2)

FCH:	102048830(EYA2)

CCRI:

104165848(EYA2)

NNT:	104412919(EYA2)

SHAB:

115615290(EYA2)

ACUN:

113487508(EYA2)

TALA:

104358966(EYA2)

ACHC:

115339720(EYA2)

HALD:

104324229(EYA2)

HLE:	104833118(EYA2)

AGEN:

126045695

HHAR:

128142469(EYA2)

GCL:

127023153

CSTI:

104557231(EYA2)

LDI:	104344757(EYA2)

MNB:	103777020(EYA2)

DPUB:

104307549(EYA2)

PPUS:

135188453(EYA2)

AVIT:

104267981(EYA2)

BRHI:

104501320(EYA2)

EGZ:	104124932(EYA2)

NNI:	104019933(EYA2)

PCRI:

104038967(EYA2)

PCAO:

104043231(EYA2)

PADL:

103919254(EYA2)

AFOR:

103901335(EYA2)

FGA:	104072836(EYA2)

GSTE:

104263443

CBOY:

140659598(EYA2)

CLV:	102085745(EYA2)

MUI:	104539705(EYA2)

PGUU:

104468893(EYA2)

PLET:

104620053(EYA2)

EHS:	104517009(EYA2)

CMAC:

104483010(EYA2)

CUCA:

104065119(EYA2)

TEO:	104378767(EYA2)

BREG:

104641153(EYA2) 104641817

OHA:	104328764(EYA2)

ACAR:

104527330(EYA2)

CPEA:

104389650(EYA2)

CVF:	104289030(EYA2)

RTD:	128916776(EYA2)

CRID:

134522491(EYA2)

AAM:	106500125(EYA2)

AROW:

112961904(EYA2)

NPD:	112949751(EYA2)

TGT:	104571458(EYA2)

DNE:	112979073(EYA2)

SCAM:

104141679(EYA2)

ASN:	102378750(EYA2)

AMJ:	106736722(EYA2)

CPOO:

109313145(EYA2)

GGN:	109292440(EYA2)

PSS:	102445259(EYA2)

CMY:	102944211(EYA2)

CCAY:

125622001(EYA2)

DCC:	119842381(EYA2)

CPIC:

101934544(EYA2)

TST:	117885727(EYA2)

CABI:

116817357(EYA2)

MRV:	120380410(EYA2)

ACS:	100558675(eya2)

ASAO:

132773165(EYA2)

PVT:	110071783(EYA2)

SUND:

121929916(EYA2)

PBI:	103051331(EYA2)

PMUR:

107288073(EYA2)

CTIG:

120311592(EYA2)

TSR:	106541321(EYA2)

PGUT:

117663589(EYA2)

APRI:

131195401(EYA2)

PTEX:

113434383(EYA2)

NSS:	113410436(EYA2)

VKO:	123028430(EYA2)

PMUA:

114599605(EYA2)

PRAF:

128416431(EYA2)

ZVI:	118088587(EYA2)

HCG:	128323711(EYA2)

GJA:

107112006

STOW:

125432815(EYA2)

EMC:	129331066(EYA2)

XLA:	108701771 108702587(eya2.S)

XTR:	100037919(eya2)

NPR:	108800391(EYA2)

RTEM:

120919315(EYA2)

BBUF:

121004657(EYA2)

BGAR:

122940295(EYA2)

PWL:	138303913(EYA2)

MUO:	115476504(EYA2)

GSH:	117345843(EYA2)

DRE:	447819(eya2)

SRX:	107740278(eya2) 107744393

SANH:

107666141 107681273

SGH:	107560503 107587629

CCAR:

109057630 109061670

CAUA:

113050136 113104996

CGIB:

127960122 128016034

PTET:

122347400(eya2)

LROH:

127167296(eya2)

OMC:	131542862(eya2)

PPRM:

120493677(eya2)

RKG:	130104147(eya2)

MAMB:

125273355(eya2)

CIDE:

127514693

CERY:

137010806(eya2)

MASI:

127446018 127449575

TROS:

130557084(eya2)

TDW:	130424590(eya2)

MANU:

129451005(eya2)

PDAB:

135757731 135769927(eya2)

IPU:

108272155

IFU:	128614760(eya2)

PHYP:

113533177(eya2)

SMEO:

124390754(eya2)

TFD:	113643194(eya2)

TVC:	132844613(eya2)

CGAR:

128526881(eya2)

NGRA:

132885077(eya2)

TRN:	134316311(eya2)

AMEX:

103035962(eya2)

CMAO:

118808504(eya2)

EEE:	113571553(eya2)

CHAR:

105895912(eya2)

SPIL:

134093038(eya2)

TRU:

101079015

TFS:	130524903(eya2)

TNG:	GSTEN00013603G001

LCO:	104922027(eya2)

NCC:	104962784 104962792

TBEN:

117489581(eya2)

CGOB:

115008193(eya2)

PGEO:

117447368(eya2)

GACU:

117539554(eya2)

EMAC:

134883138(eya2)

ELY:	117256233(eya2)

EFO:	125894579(eya2)

PLEP:

121949512(eya2)

SLUC:

116051530(eya2)

ECRA:

117943467(eya2)

ESP:

116687740

PFLV:

114554211

GAT:	120834584(eya2)

PPUG:

119194114(eya2)

AFB:	129105601(eya2)

CLUM:

117731355(eya2)

PSWI:

130207724(eya2)

CANA:

137796217(eya2)

CVE:	137873930(eya2)

MSAM:

119886555(eya2)

SCHU:

122864194(eya2)

CUD:	121506926(eya2)

SPUL:

138605465(eya2)

LMIX:

132978196(eya2)

ALAT:

119021829(eya2)

ASTR:

137595134(eya2)

MZE:

101483071

ONL:	100693909(eya2)

OAU:	116326851(eya2)

OLA:

101169441

OML:	112145672(eya2)

CSAI:

133449278(eya2)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122834264(eya2)

PPRL:

129358347(eya2)

CVG:

107103454

CTUL:

119797000(eya2)

GMU:	124856178(eya2)

NFU:	107385380(eya2)

KMR:	108231461(eya2)

ALIM:

106517645

NWH:	119411857(eya2)

AOCE:

111576046(eya2)

EJA:	138197175(eya2)

BFRE:

138616606(eya2)

MCEP:

125007269(eya2)

CSEM:

103386715

POV:

109635341

SSEN:

122768517(eya2)

SSOE:

131460844(eya2)

HHIP:

117761752(eya2)

HSP:	118105074(eya2)

PPLT:

128462200(eya2)

SMAU:

118309616(eya2)

LCF:

108902127

SDU:

111233560

SLAL:

111655086

XGL:	120807563(eya2)

HCQ:

109521698

SSCV:

125977903(eya2)

SBIA:

133507936(eya2)

PEE:	133408507(eya2)

PTAO:

133484214(eya2)

BPEC:

110173736

ENY:	140365404(eya2)

MALB:

109973983

BSPL:

114855907(eya2)

SJO:	128355118(eya2)

SSCO:

133977292(eya2)

GMH:

115557739

SASA:

106565282 106583664

STRU:

115150107 115208364

OTW:	112255353 112267187(eya2)

OMY:	110493897 110528547(eya2)

OGO:

124004336

ONE:	115142840(eya2)

OKI:	109891438 109897787

OKE:

118388941

OMM:	135539567 135541251

OCLA:

139370661 139413852

SALP:

111961838

SNH:	120026505 120064650

CCLU:

121576024 121577983

ELS:	109614619(eya2)

OEP:	134019281(eya2)

SFM:	108936609(eya2)

PKI:

111861095

AANG:

118210511(eya2)

AROT:

135237964(eya2)

CCOG:

133109849(eya2)

LOC:

102685968

PSPA:

121298227(eya2) 121307804

ARUT:

117420767 117430960(eya2)

PSEX:

120514781(eya2)

LCM:	102364729(EYA2)

» show all

Reference

PMID:21706047

Authors

Farabaugh SM, Micalizzi DS, Jedlicka P, Zhao R, Ford HL

Title

Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-beta signaling, epithelial-mesenchymal transition, and cancer stem cell properties.

Journal

Oncogene 31:552-62 (2012)
DOI:10.1038/onc.2011.259

Sequence

[hsa:2139]

LinkDB

DBGET integrated database retrieval system