KEGG ORTHOLOGY: K18045

ORTHOLOGY: K18045

Entry

K18045                      KO

Symbol

SIW14, OCA3

Name

tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K18045  SIW14, OCA3; tyrosine-protein phosphatase SIW14
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K18045  SIW14, OCA3; tyrosine-protein phosphatase SIW14
Protein phosphatases and associated proteins [BR:ko01009]
Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Atypical DSPs
    K18045  SIW14, OCA3; tyrosine-protein phosphatase SIW14

Other DBs

COG:

COG2365

GO:

0004725

Genes

OSA:	128684019 4340447 4346470 9270659

DOSA:

Os02g0771400 Os06g0208700 Os09g0135700

OBR:	102702631 102704359 102712730 102714694

OGL:	127757272 127763206 127776372 127784614

BDI:	100824200 100828674 104584405

ATS:	109742260 109773384 109786013

TDC:	119301119 119308655 119318038 119323088 119329296 119337219

TAES:

123087372 123087424 123103331 123111531 123119145 123120791 123128532 123128533 123138398 123145651 123145652 123149082 123157032 123165070

TUA:	125508941 125518001

HVG:	123396084 123402315 123411346

LPER:

127300351 127305999 127317776 127333141 127342410

LRD:	124654435 124666572 124678396 124678585 124678903 124681042 124681043 124688455 124688456 124694669 124700300

SBI:	110430736 8062593 8078946

ZMA:	100191574 100283147 100283963 100285379 541689

MFLO:

136467837 136477008 136478172 136521448 136522704 136527933

SITA:

101755591 101755610 101783627 101785889

SVS:	117839625 117843501 117848637 117852115

PVIR:

120643361 120657321 120666070 120670445 120699322 120704619

PHAI:

112885047 112890142

PAUA:

133896625 133919895 133921120 133926461 133930661

TANG:

140758221 140760147 140769071 140771702

PDA:	103709382 103710597 103714027 103717058 103718517

EGU:	105037509 105039094 105049645 105050192 105061032

MUS:	103972619 103974109 103989480 135599078 135610770 135616557 135617326 135625522

ZOF:	121970903 121976725 121979836 121986848 121999520 122000753 122004453 122007837 122008301 122010390 122011202 122014795 122016057 122016907 122025384 122056591

DCT:	110096794 110100288 110105519 110110647 110115106

PEQ:	110022651 110023300 110026233 110038730

AOF:	109829373 109841069 109846017

ATH:	AT1G05000(PFA-DSP1) AT2G32960(PFA-DSP2) AT3G02800(PFA-DSP3) AT4G03960(PFA-DSP4) AT5G16480(PFA-DSP5)

ALY:	9307790 9308744 9315493 9318319 9328321

CRB:	17881121 17884421 17887582 17893934 17897731

CSAT:

104700158 104705937 104707568 104717244 104735679 104739034 104744360 104749568 104749569 104749570 104749572 104754645 104759073 104762842 104763898 104769928 104773278 104778815 104786281

EUS:	EUTSA_v10008768mg EUTSA_v10014713mg EUTSA_v10017110mg EUTSA_v10021545mg EUTSA_v10028976mg

BRP:	103839853 103843604 103844186 103846330 103851044 103858984 103865238 103867587 103870892

BNA:	106357296 106366906 106370513 106372215 106377113 106385217 106391973 106401190 106423642 106423690 106423796 106427654 106443865 106451276 106453212 125578330 125583345 125606812 125609157

BOE:	106292559 106293724 106295481 106312917 106315640 106324982 106332348 106337294 106337642

RSZ:	108807005 108807059 108809806 108812609 108813164 108817227 108825657 108842779 108854986 108860531 108862237

THJ:	104801010 104813361 104813479 104816034 104820916 104827175

CPAP:

110808098 110808813 110809406

CIT:	102610945 102612228 102621872

CIC:	CICLE_v100128102m CICLE_v10016646mg CICLE_v10016786mg

PVY:	116125052 116142973

MINC:

123196470 123207600 123219162 123220415 123224439

TCC:	18597241 18599373 18612360

GRA:	105773343 105777033 105780606 105782509 105789975 105800173 105802581

GHI:	107910064 107912952 107918574 107924920 107935344 107954049 107954775 107955054 107957213 107959413 107959484 107962060 107962066 121219524

GAB:	108453508 108458098 108458153 108462962 108465939 108470879 108485561

HSYR:

120123320 120156217 120161275 120162026 120164454 120164549 120165840 120170224 120170550 120171111 120183030 120190095 120191273

DZI:	111274041 111277711 111283623 111293903 111296785 111305592 111314545

EGR:	104434799 104435030 104445667

RARG:

115747637 115748420 115757081

GMX:	100785520 100785746 100787713 100799968 100808199 100814279

GSJ:	114370870 114385499 114397517 114400122 114420208 114425165

PVU:	137806741 137823732 137824121 137828455

VRA:	106758696 106765324 106768228 106770566

VAR:	108323079 108326958 108338532 108342460

VUN:	114178843 114185940 114189460 114194767

VUM:	124828459 124833621 124846771 124847921

CCAJ:

109802211 109804920 109809353 109815576

APRC:

113846011 113847161 113863424 113873311

MTR:	11406089 11434679 11440106

TPRA:

123889457 123910240 123924586 123924758

CAM:	101489868 101507887 101511093

VVO:	131612179 131612182 131616023 131621095 131626846

LJA:	130714292 130728338 130733500

ADU:	107465896 107466384 107469424 107482959 107485972 107496894

AIP:	107609125 107617392 107621933 107635141 107636548 107638665

AHF:	112702267 112706079 112711035 112718203 112722851 112741263 112744256 112766107 112779820 112783687 112795961 112797563

LANG:

109335324 109337007 109353659 109356784 109361098 109362286

PCIN:

129285482 129285584 129302453 129304397 129318438

QSA:	O6P43_007759 O6P43_011328 O6P43_014548 O6P43_020789 O6P43_031297

FVE:	101293681 101312940

AANS:

126797953 126800902

RCN:	112190394 112192515 112200585

PPER:

18772816 18778180 18783703 18792324

PMUM:

103318790 103324453 103329157 103341693

PAVI:

110751452 110760443 110764511 110771460

PDUL:

117617679 117622201 117626443 117629887

MDM:	103403208 103411279 103412602 103417176 103434267 103434463 103451148

MSYL:

126582408(LOC126582408) 126584842(LOC126584842) 126593597(LOC126593597) 126609582(LOC126609582) 126619116(LOC126619116) 126623981(LOC126623981)

PXB:	103930399 103946642 103948239 103954991

PCOX:

137707836 137722593 137725970 137726530 137730269 137731212 137740974 137745985

ZJU:	107414648 107417147

MNT:	21388309 21397286 21398239

CSAV:

115701326 115721353

HLP:	133790513 133794850 133817495

CSV:	101209768 101211082 101222170

CMO:	103487232 103491358 103496354

BHJ:	120071469 120078115 120088402

MCHA:

111016668 111018115 111020451

CMAX:

111468382 111469661 111483891 111485819 111485922 111498659

CMOS:

111437030 111441090 111448944 111451380 111454884 111461651

CPEP:

111777677 111780322 111784063 111793640 111795554 111811868

RCU:	8260998 8274297

MEAN:

126654464 126657417 126682852

JCU:	105640864 105644871 105649279

HBR:	110639105 110642548 110650985 110654473 110656682 110659898

MESC:

110627274 110627875 110629330 110630269

POP:	18097292 18104237 7458283 7468529 7485409

PEU:	105108146 105114158 105114924 105118648 105141479

PALZ:

118032000 118036343 118040617 118049389 118058406

PNZ:	133669372 133681794 133691713 133703525

JRE:	108981553 108981909 108982966 108995853 108996427 109006072

CILL:

122277004 122278840 122303751 122306626 122315318 122318092

CAVE:

132170485 132171884 132182501

AGLU:

133851655 133861259 133869601

QSU:	112008997 112018947 112025447

QLO:	115957874 115980111 115988387 115991452

CSAA:

142606668 142633791 142640917

TWL:	119989093 119991994 119999468 120007273 120008100

VVI:	100247948 100251662 100256357

VRI:	117912307 117923291 117923414 117927274

SLY:	101249420 101256867 101261120 101264534

SPEN:

107005089 107015936 107020960 107023980

SOT:	102582305 102584322 102595747 102605767 107062157

SSTN:

125844159 125856532 125866810 125868232 125877118

SDUL:

129887486 129893120 129896289

SVER:

125817874 125819558 125833021 125839812

CANN:

107850671 107851382 107855270 107871422 107872032

LBB:	132612578 132615123 132617629 132636459 132639159 132640060

NTA:	107759579 107759911 107761062 107770751 107772736 107783739 107791585 107810124 107821281 107824965 107830889

NSY:	104210711 104219015 104220543 104223077 104235489 104248044

NTO:	104091861 104095892 104099767 104103326 104117583 104119829

NAU:	109212568 109216359 109225417 109226249 109228676 109244925

INI:	109149705 109157390 109157396 109164547 109164608 109188223

ITR:	115996732 116004997 116022374 116027707 116031339

SIND:

105175308 105178572

OEU:	111370650 111387272 111387273 111390808 111395492

EGT:	105961728 105968517

SSPL:

121742465 121744430 121754185 121758411 121777630

SMIL:

130985827 131009417

SHIS:

125191119 125192664 125205384

APAN:

127247704 127249557 127266083

PHUA:

140985103

PEBU:

140813193 140814468

PTAB:

142518569 142527974

CARB:

113689881 113708589 113708760 113709434 113710399 113743676

HAN:	110910492 110914959 110915803 110938134 118490640

BHW:	143533330 143586412 143597622 143601017 143602757 143604468 143605217 143613013 143616891 143618122 143625869 143635459

ECAD:

122589723 122593530 122602114 122604051 122605324

LSV:	111877742(LOC111877742) 111880008(LOC111880008) 111890982(LOC111890982) 111902803(LOC111902803) 111904964(LOC111904964)

CCAV:

112500813(LOC112500813) 112507204(LOC112507204) 112508852(LOC112508852) 112509587(LOC112509587) 112518518(LOC112518518)

DCR:	108223210 108223431 108224869

AGRV:

141706666 141707017 141711098

CSIN:

114267501 114304615 114306546 114317274 114322989

RVL:	131301086 131323004 131330731

AEW:	130751163 130789056 130790866

DLT:	127792129 127793813 127794220

CFLO:

132307411 132308005

BVG:	104890226(LOC104890226) 104898073(LOC104898073) 104900469(LOC104900469) 104900927(LOC104900927) 104902722(LOC104902722)

SOE:	110777272 110791434 110803802

CQI:	110687421 110691903 110701095 110701956 110731283 110736424

CALB:

145558259(LOC145558259) 145574280(LOC145574280) 145577569(LOC145577569) 145587385(LOC145587385) 145606151(LOC145606151) 145611616(LOC145611616) 145620364(LOC145620364) 145628575(LOC145628575) 145635419(LOC145635419)

ATRI:

130797000 130802852 130815332 130817885

SLAF:

141596750 141619225 141642524 141646671 141657726

MOF:	131149116 131153221

NNU:	104594114 104605297 104606507

MING:

122069668 122070132 122083976

TSS:	122638891 122644041 122658065 122669897

PSOM:

113283993 113288049 113303762 113307806 113311100 113315574 113317195 113323351 113332172 113332174 113334330 113348537 113361155

MSIN:

131239568

ACAK:

137939350 137962360 137962975 137966231

NCOL:

116247268 116257791

ATR:	18424859 18448284 18995747

CJF:	131033332 131059982

SMO:	SELMODRAFT_107045 SELMODRAFT_231635 SELMODRAFT_267170 SELMODRAFT_412771 SELMODRAFT_6827 SELMODRAFT_6925

PPP:	112285768 112290047

CME:	CYME_CMS432C

SCE:	YNL032W(SIW14)

SEUB:

DI49_4705

SPAO:

SPAR_N02740

AGO:	AGOS_ADL204W

ERC:

Ecym_3336

KLA:	KLLA0_E08581g

KMX:	KLMA_80121(SIW14)

LTH:	KLTH0G10626g

VPO:	Kpol_1003p45

ZRO:	ZYRO0A02134g

CGR:	2891690(GVI51_M06721)

NCS:	NCAS_0G03690(NCAS0G03690)

NDI:	NDAI_0G00770(NDAI0G00770)

TPF:	TPHA_0C03470(TPHA0C03470)

TBL:	TBLA_0B07200(TBLA0B07200)

TGB:	HG536_0A02220

TDL:	TDEL_0G02260(TDEL0G02260)

KAF:	KAFR_0H03210(KAFR0H03210)

KNG:	KNAG_0H01880(KNAG0H01880)

ZMK:	HG535_0D01940

SLUD:

SCDLUD_002743

DHA:	DEHA2A10582g

PIC:	PICST_61269(SIW14)

PGU:	PGUG_01974

SPAA:

SPAPADRAFT_59413

LEL:	PVL30_002935(SIW14_1)

LBG:	92206670(LODBEIA_P14740)

COT:	CORT_0D03330

CAL:	CAALFM_CR06830CA(SIW14)

CTP:	CTRG_00678

CDU:	CD36_32370

CTEN:

18249288(SIW14)

CLU:	CLUG_04787

CLUS:

A9F13_27g00077

CAUR:

CJI96_0002744

ASAU:

88174700(PUMCH_003637)

PPA:	PAS_chr2-2_0197

PKZ:	C5L36_0C02180

BNN:	FOA43_002815(SIW14)

BBRX:

BRETT_002656

OPA:	HPODL_01322

YLI:	2910893(YALI2_D00969g)

SLB:	AWJ20_1368(SIW14)

NCR:

NCU03333

NTE:	NEUTE1DRAFT117516(NEUTE1DRAFT_117516)

SMP:	10804059(SMAC4_12110)

PAN:	PODANSg6460

PBEL:

QC761_306210(SIW14)

PPSD:

87908821(SIW14)

PPSP:

QC763_306210(SIW14)

PPSA:

QC764_306210(SIW14)

TTT:	THITE_2123435

MTM:	MYCTH_2311715

CTHR:

CTHT_0001650

RTHE:

98127756(VTJ83DRAFT_6404)

MGR:

MGG_12093

PGRI:

PgNI_07024

TMN:	UCRPA7_877

SSCK:

SPSK_00286

FGR:	FGSG_01671

FPU:	FPSE_11489

FPOA:

FPOAC1_001793

FVN:	FVRRES_02006

FVR:	FVEG_09761

FOX:	FOXG_11036

NHE:	NECHADRAFT_30066

FFC:	NCS54_00020200

FKR:	NCS57_00018000

FMU:	J7337_000206

TRE:	TRIREDRAFT_41428

TRR:	M419DRAFT_123313

TATV:

25777319(TrAtP1_009377)

TASP:

36615119(TrAFT101_004798)

MAW:	19247077(SIW14_1)

MAJ:

MAA_08575

MBRN:

26243916(DSP1)

PCHM:

VFPPC_17604

UVI:	66066377(UV8b_05600)

CMT:

CCM_02160

AMUS:

LMH87_003251

PLJ:	28889466(PLICBS_008099)

PTKZ:

JDV02_010365(SIW14)

DCON:

63720799(DCS_08156)

VAL:	VDBG_05814

VDA:	VDAG_07748

CFJ:	CFIO01_07957

CHIG:

CH63R_10701

CDET:

87943775(CDEST_07272)

SAPO:

SAPIO_CDS0924

ELA:	UCREL1_8273

SSL:	SS1G_03937

BFU:	BCIN_04g02120

MBE:

MBM_08023

PSCO:

LY89DRAFT_221848

ANI:	ANIA_04426

AFM:	AFUA_4G07000

ACT:	ACLA_046300

NFI:	NFIA_109230

AOR:	AO090023000886

ANG:	An04g01410

AFV:	AFLA_007239

ALUC:

AKAW2_51172A

ACHE:

ACHE_20599A

APUU:

APUU_70595A

CIM:	CIMG_04137

CPW:	9693736(D8B26_003560)

URE:	UREG_05573

ABE:

ARB_01614

TVE:

TRV_03540

PBL:	PAAG_12430

PBN:	PADG_08286

AJE:	HCAG_05600

BGH:	BDBG_02644

PNO:	SNOG_04979

PTE:

PTT_19698

PTRR:

6342358(PtrM4_091380)

BZE:	COCCADRAFT_95609

BSC:	COCSADRAFT_223626

BOR:	COCMIDRAFT_25151

AALT:

CC77DRAFT_232295

ADAC:

96084427(ACET3X_004105)

ARAB:

EKO05_0007540

ZTR:	MYCGRDRAFT_27411(MgPTP7)

PFJ:	MYCFIDRAFT_163273

FFU:	CLAFUR5_13872

CBET:

CB0940_04916

BCOM:

BAUCODRAFT_53222

NPA:	UCRNP2_5759

TML:	GSTUM_00004951001

SPO:	2540134(siw14)

SOM:	SOMG_00943

CNE:	CND03710 CNF04310 CNG02810

CNB:	CNBD2610 CNBF0570 CNBG1960

CNG:	CNAG_01254 CNAG_03296 CNAG_06587

CGI:	CGB_D6420C CGB_F0520C CGB_G2620W

CDEU:

CNBG_0819 CNBG_1972 CNBG_2303

CDEC:

89987057(IAS62_000281) 89989629(IAS62_002856) 89990927(IAS62_004155)

CTEG:

91987425(I308_100567) 91990434(I308_103578) 91991063(I308_104207)

CBAS:

91980333(I312_100285) 91984153(I312_104108) 91985031(I312_104986)

CDEP:

91084497(L203_100281) 91088235(L203_104025) 91089375(L203_105166)

KMG:	30163077(I203_102069) 30166432(I203_102503) 30168007(I203_107725)

KNE:	92180168(IAR55_002910) 92182222(IAR55_004964) 92182916(IAR55_005658)

KDJ:	28966034(I303_101533) 28968946(I303_105306) 28970967(I303_108405)

KBI:	30208724(I302_100948) 30210292(I302_106842) 30212572(I302_109030)

KPIN:

30170738(I206_104830) 30174417(I206_107714) 30175014(I206_101385)

KSH:	87954293(IL334_002162) 87957003(IL334_004872) 87958771(IL334_006641)

KER:	91101425(V865_002621) 91101867(V865_003063) 91105058(V865_006257)

KSN:	43585516(CI109_103027) 43591208(CI109_106376)

KBO:	90014823(L199_003839) 90017973(L199_006989)

KEP:	91092926(L201_002254) 91094076(L201_003406) 91098393(L201_007725)

TMS:	TREMEDRAFT_26965 TREMEDRAFT_44410

TASA:

A1Q1_01573 A1Q1_07689

CCAC:

CcaHIS019_0109840(CcaverHIS019_0109840) CcaHIS019_0111800(SIW14) CcaHIS019_0112540(CcaverHIS019_0112540)

UMA:	UMAG_03985

PFP:	PFL1_00973 PFL1_02434

MGL:	MGL_2007 MGL_2636

MRT:	MRET_0450 MRET_2783

MSYM:

MSY001_0204 MSY001_3172

MJP:	85224529(MJAP1_000880) 85224618(SIW14)

MVES:

80900171(MVES1_000664) 80901236(SIW14) 80903002(MVES1_003491)

PGR:	PGTG_03141 PGTG_07166

PTRC:

PtA15_11A45 PtA15_1A876

PSTR:

Pst134EA_000216 Pst134EA_017903

MLR:	MELLADRAFT_30357 MELLADRAFT_77769

RIE:	OCT59_004369 OCT59_027015

DDI:	DDB_G0285909

DFA:

DFA_07185

ACAN:

ACA1_031870 ACA1_121530

PIF:	PITG_00573 PITG_06814

PSOJ:

PHYSODRAFT_478748 PHYSODRAFT_483936

BLAC:

94347574(CCR75_003810)

SPAR:

SPRG_12971 SPRG_13162 SPRG_13695 SPRG_15372

TBR:	Tb09.v1.0350

TBG:	TbgDal_IX4240

TCR:	504033.170 510339.14

LMA:	LMJF_04_0560

LIF:	LINJ_04_0550

LDO:	LDBPK_040550

LMI:	LMXM_04_0560

LMAT:

92517327(LSCM1_07445)

LBZ:	LBRM_04_0610

LPAN:

LPMP_040520

LOI:	92363333(LSCM4_07513)

LEIS:

94182909(GH5_07679)

LENR:

94175098(CUR178_07953)

LEIN:

94190775(JIQ42_07182)

PHET:

94293265(JKF63_07248)

NGR:	NAEGRDRAFT_31755 NAEGRDRAFT_75564

TVA:	4748246(TVAGG3_0076520)

EHX:	EMIHUDRAFT_47311 EMIHUDRAFT_57384 EMIHUDRAFT_60319 EMIHUDRAFT_62039 EMIHUDRAFT_78296

GTT:	GUITHDRAFT_156243 GUITHDRAFT_45910 GUITHDRAFT_82431

PVG:	CRN77_09835

PHAU:

PH4a_00830

PCIB:

F9282_12740

PFQ:	QQ39_01440

PFS:

PFLU_0050

PAZO:

AYR47_07325

PSK:	U771_00465

PYM:	AK972_5881

ORB:	IPMB12_02905

SALV:

SALWKB2_0217

LLU:	AKJ09_03828

LUO:	HHL09_10505

GMS:	SOIL9_24490

HBS:	IPV69_26480

SUS:

Acid_4894

NIA:	A8C56_18055

EAO:

BD94_2644

EEN:	BBD30_13595

ELB:	VO54_00070

EGM:	AYC65_04785

ELZ:	FCS00_17920

CHRY:

CEY12_07895

» show all

Reference

PMID:15020461

Authors

Care A, Vousden KA, Binley KM, Radcliffe P, Trevethick J, Mannazzu I, Sudbery PE

Title

A synthetic lethal screen identifies a role for the cortical actin patch/endocytosis complex in the response to nutrient deprivation in Saccharomyces cerevisiae.

Journal

Genetics 166:707-19 (2004)
DOI:10.1534/genetics.166.2.707

Sequence

[sce:YNL032W]

Reference

PMID:21409566

Authors

Roma-Mateo C, Sacristan-Reviriego A, Beresford NJ, Caparros-Martin JA, Culianez-Macia FA, Martin H, Molina M, Tabernero L, Pulido R

Title

Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms.

Journal

Mol Genet Genomics 285:341-54 (2011)
DOI:10.1007/s00438-011-0611-6

Sequence

[sce:YNL032W]

LinkDB

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