KEGG   ORTHOLOGY: K21618
Entry
K21618                      KO                                     
Symbol
DLD3
Name
(R)-2-hydroxyglutarate---pyruvate transhydrogenase [EC:1.1.99.40]
Pathway
map00620  Pyruvate metabolism
map01100  Metabolic pathways
Reaction
R11593  (R)-2-hydroxyglutarate:pyruvate oxidoreductase [(R)-lactate-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K21618  DLD3; (R)-2-hydroxyglutarate---pyruvate transhydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.99  With unknown physiological acceptors
    1.1.99.40  (R)-2-hydroxyglutarate---pyruvate transhydrogenase
     K21618  DLD3; (R)-2-hydroxyglutarate---pyruvate transhydrogenase
Other DBs
COG: COG0277
Genes
AJC: 117101910
SCE: YDL178W(DLD2) YEL071W(DLD3)
SEUB: DI49_0901 DI49_5679
SPAO: SPAR_D00650 SPAR_E00030
AGO: AGOS_ACL021C
ERC: Ecym_8034
KLA: KLLA0_F05753g
KMX: KLMA_60482(DLD2)
LTH: KLTH0A05280g
ZRO: ZYRO0C09218g
CGR: 2889585(GVI51_J06149)
NCS: NCAS_0E03520(NCAS0E03520) NCAS_0H00160(NCAS0H00160)
NDI: NDAI_0A03060(NDAI0A03060) NDAI_0H04030(NDAI0H04030)
TPF: TPHA_0A03280(TPHA0A03280)
TBL: TBLA_0F01970(TBLA0F01970)
TGB: HG536_0C05350 HG536_0G04870
TDL: TDEL_0A08020(TDEL0A08020) TDEL_0E05730(TDEL0E05730) TDEL_0H01580(TDEL0H01580)
KAF: KAFR_0L01170(KAFR0L01170)
KNG: KNAG_0B02950(KNAG0B02950)
ZMK: HG535_0C06490 HG535_0G01630
SLUD: SCDLUD_000314
DHA: DEHA2B10142g
PIC: PICST_89565(DLD2)
PGU: PGUG_01680
SPAA: SPAPADRAFT_51529
LEL: PVL30_002082(DLD2)
LBG: 92207494(LODBEIA_P22980)
CAL: CAALFM_C303040WA(AIP2)
CTP: CTRG_02583
COT: CORT_0B03720
CDU: CD36_83020
CTEN: 18245646(DLD2)
CLU: CLUG_05807
CLUS: A9F13_05g01430
CAUR: CJI96_0000621
ASAU: 88173052(PUMCH_001987)
PPA: PAS_chr3_0674
PKZ: C5L36_0A01180
BNN: FOA43_004635(DLD2)
BBRX: BRETT_001775
OPA: HPODL_02835
YLI: 2909313(YALI2_C00112g)
SLB: AWJ20_5329(DLD2)
NCR: NCU06441
NTE: NEUTE1DRAFT146088(NEUTE1DRAFT_146088)
SMP: 90947621(SMAC4_02202)
PAN: PODANSg5397
PBEL: QC761_709950(DLD2)
PPSD: QC762_709950(DLD2)
PPSP: QC763_709950(DLD2)
PPSA: QC764_709950(DLD2)
TTT: THITE_2119881
MTM: MYCTH_2303826
CTHR: CTHT_0069840
RTHE: 98121935(VTJ83DRAFT_1162)
MGR: MGG_12830
PPEI: PpBr36_06064
PGRI: PgNI_00884
TMN: UCRPA7_2227
SSCK: SPSK_03231
FGR: FGSG_13110
FPU: FPSE_01095
FPOA: FPOAC1_011061
FVN: FVRRES_12081
FVR: FVEG_05295
FOX: FOXG_02132
NHE: NECHADRAFT_68595
FKR: NCS57_00622200
FMU: J7337_002466
TRE: TRIREDRAFT_76013
TRR: M419DRAFT_23753
TATV: 90959529(TrAtP1_004570)
TASP: 90966426(TrAFT101_003987)
MAJ: MAA_05955
MBRN: 26238479(G6M90_00g014890)
PCHM: VFPPC_02734
CMT: CCM_01480
AMUS: LMH87_004156
PLJ: 28887755(PLICBS_002988)
PTKZ: JDV02_000856(DLD2_2)
VAL: VDBG_02828
VDA: VDAG_03746
CFJ: CFIO01_10052
CLUP: CLUP02_03998
CHIG: CH63R_02967
CDET: 87937722(CDEST_01219)
SAPO: SAPIO_CDS5745
ELA: UCREL1_1651
PFY: PFICI_11909
SSL: SS1G_07702
BFU: BCIN_15g02730
MBE: MBM_06930
PSCO: LY89DRAFT_60738
GLZ: GLAREA_06857
ANI: ANIA_11045
AFM: AFUA_5G02230
ACT: ACLA_003010
NFI: NFIA_039880
AOR: AO090102000291
ANG: An02g10670
AFV: AFLA_011734
ALUC: AKAW2_10900S
ACHE: ACHE_51025S
APUU: APUU_41540A
PCS: N7525_008041
PDP: PDIP_48140
POU: POX_a00075
TMF: EYB26_004184
TRG: TRUGW13939_08504
CIM: CIMG_06424
CPW: 9695228(D8B26_006327)
URE: UREG_03983
ABE: ARB_00809
TVE: TRV_00678
PBL: PAAG_07804
PBN: PADG_02733
AJE: HCAG_00349
BGH: BDBG_01546
PNO: SNOG_11128
PTE: PTT_18111
PTRR: 6347812(PtrM4_127580)
BZE: COCCADRAFT_5082
BSC: COCSADRAFT_82172
BOR: COCMIDRAFT_93512
AALT: CC77DRAFT_741863
ADAC: 96083637(ACET3X_003315)
ARAB: EKO05_0009888
ZTR: MYCGRDRAFT_74344
PFJ: MYCFIDRAFT_215437
FFU: CLAFUR5_06940
CBET: CB0940_09722
BCOM: BAUCODRAFT_150031
NPA: UCRNP2_192
TML: GSTUM_00011704001
SPO: 2541151(dld2)
SOM: SOMG_01473(dld2)
CNE: CNB01750 CNK01540
CNB: CNBB3980 CNBK2000
CNG: CNAG_02664 CNAG_03676
CGI: CGB_B5760W CGB_K2470C
CDEU: CNBG_0079 CNBG_3125
CDEC: 89990003(IAS62_003230) 89991654(IAS62_004883)
CTEG: 91989324(I308_102467) 91992008(I308_105152)
CBAS: 91982939(I312_102893) 91985432(I312_105387)
CDEP: 91090398(L203_106190)
KMG: 30167388(I203_103053)
KNE: 92177724(IAR55_000464) 92181969(IAR55_004711)
KDJ: 28971234(I303_108139)
KBI: 30212129(I302_108592)
KPIN: 30174042(I206_107346)
KSH: 87958474(IL334_006344)
KER: 91100881(V865_002077)
KSN: 43592117(CI109_104473)
TMS: TREMEDRAFT_44101
TASA: A1Q1_08226
CCAC: CcaHIS019_0209500(DLD2)
TVS: TRAVEDRAFT_159410 TRAVEDRAFT_16748
DSQ: DICSQDRAFT_75448
PCO: PHACADRAFT_180107
SHS: STEHIDRAFT_117557
HIR: HETIRDRAFT_307493
PSQ: PUNSTDRAFT_58716
ADL: AURDEDRAFT_111902
FME: FOMMEDRAFT_121754
GTR: GLOTRDRAFT_31335
RSX: RhiXN_00802
LBC: LACBIDRAFT_175753
CCI: CC1G_03657
ABP: AGABI1DRAFT110375(AGABI1DRAFT_110375)
ABV: AGABI2DRAFT60921(AGABI2DRAFT_60921)
PCUB: JR316_0000843
MRR: Moror_99
MORE: E1B28_001223
SCM: SCHCO_02609927(SCHCODRAFT_02609927)
CPUT: CONPUDRAFT_115042
SLA: SERLADRAFT_358276 SERLADRAFT_456132
WSE: WALSEDRAFT_58973
WIC: J056_004400
UMA: UMAG_01314
PFP: PFL1_04079
SGRA: EX895_001713
MGL: MGL_2442
MRT: MRET_3321
MSYM: MSY001_1771
PGR: PGTG_05096
PTRC: PtA15_3A252
PSTR: Pst134EA_007528
MLR: MELLADRAFT_49675
RIE: OCT59_020620
 » show all
Reference
PMID:26774271
  Authors
Becker-Kettern J, Paczia N, Conrotte JF, Kay DP, Guignard C, Jung PP, Linster CL
  Title
Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
  Journal
J Biol Chem 291:6036-58 (2016)
DOI:10.1074/jbc.M115.704494
  Sequence
[sce:YEL071W YDL178W]
LinkDB

DBGET integrated database retrieval system