Kosakonia sp. SMBL-WEM22: HF650_03890
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Entry
HF650_03890 CDS
T08549
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
kob
Kosakonia sp. SMBL-WEM22
Pathway
kob00260
Glycine, serine and threonine metabolism
kob00261
Monobactam biosynthesis
kob00270
Cysteine and methionine metabolism
kob00300
Lysine biosynthesis
kob01100
Metabolic pathways
kob01110
Biosynthesis of secondary metabolites
kob01120
Microbial metabolism in diverse environments
kob01230
Biosynthesis of amino acids
Module
kob_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kob_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
kob_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
kob00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HF650_03890 (thrA)
00270 Cysteine and methionine metabolism
HF650_03890 (thrA)
00300 Lysine biosynthesis
HF650_03890 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HF650_03890 (thrA)
Enzymes [BR:
kob01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HF650_03890 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HF650_03890 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
ChAPs
Sacchrp_dh_NADP
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QNQ18954
UniProt:
A0A7H0M9J3
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All DBs
Position
798142..800604
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
IPNISDAERIFSELLQGLSDAQPGFLLAQLKTVVDAEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGLLEARGHKVTVIDPVEKLLAVGHYLESTVDIAESTRRIEASRIP
QDHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGATSD
DDALPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFATMSRNGISVVLITQSSSEYSISF
CVPQSDCARAQRAMNEEFYLELKEGLLEPLAVMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKSKHIDLRVCGVANSRALLTNVHGLNLDNWQAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRRAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATKVA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELTDIVIEPVLPASFDDSGEVDSFMA
RLPSLDDEFASRVAKARDAGNVLRYVGNIEEDGTCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagttcggcggtacatcagtggcaaatgcggagcgttttctgcgtgtt
gccgatattctggaaagtaatgccaggcagggacaagtcgcaaccgtactctctgcaccc
gccaaaattactaaccatcttgtcgcgatgattgaaaagaccatctccggacaggatgcg
attcccaacattagcgatgcagagcgtattttctccgagctgctgcaggggctttcagat
gcgcagcctggttttctgctcgcacaacttaaaaccgtggttgatgctgaatttgcgcag
atcaaacatgtcctgcacggcatcagtctgctgggtcagtgtccggacagcatcaatgct
gcgctcatctgccggggtgaaaaactctctatcgcgattatggccgggctgctggaagca
cgtggtcacaaagtgacggttatcgatccggtcgaaaaattactcgctgtcgggcactat
ctcgaatcaacggtcgatatcgctgaatccacacgtcgtatcgaagccagccgcattccg
caggatcatatggtgctgatggccggtttcaccgcgggcaatgagaagggcgaactggta
gtgctcgggcgtaacggctccgattactctgccgccgtgctggctgcatgtttacgcgct
gactgttgtgaaatctggactgatgtcgacggcgtatatacctgtgacccgcgccaggtg
ccggacgccaggctgctgaagtcaatgtcctatcaggaagccatggagctctcctacttc
ggcgctaaagttcttcacccccgcaccattacccccatcgcccaatttcagatcccctgc
ctgattaaaaataccggcaacccgcaagcaccgggtacgctgattggcgctacttcggat
gatgacgcattgccggttaaggggatctccaatctcaacaatatggcgatgttcagcgtt
tccggcccggggatgaaagggatggtcggcatggccgcccgcgtcttcgccaccatgtcg
cgcaacggcatttccgtcgtgctgatcacccaatcctcatccgagtacagcatcagcttc
tgtgtgccgcagtccgactgcgcccgtgcgcagcgtgcgatgaatgaagagttctatctt
gaactgaaagagggtctgctggagccgctcgccgtgatggagcgtctggcgatcatctcc
gttgttggcgacggcatgcgcaccttacgcggcatctcggcgaaattctttgccgctctg
gcgcgcgccaatatcaatatcgtggcgattgcccagggctcttctgagcgctcgatctcc
gttgtggtcagcaatgacgatgcaacgaccggcgtgcgcgtcactcatcagatgttgttc
aacaccgatcaggtgattgaagtctttgttatcggtgttggcggcgtcggcggcgcacta
ctggaacagctgaagcgccagcaaacgtggctgaagagtaagcatatcgatctgcgcgtc
tgcggcgttgctaactcgagagcgctgctgaccaatgtgcatggcctgaacctggataac
tggcaggcagagctcgcggaagcgaaggagccgttcaacctcggccgactgattcgcctg
gtgaaggagtaccatctgctgaacccggtgatcgtcgattgcacctccaaccaggcagtc
gccgatcagtatgccgacttcctgcgcgaaggtttccacgtcgttacgccgaacaaaaaa
gcgaacacctcgtcgatggattactaccatcagctgcgccgcgccgcagagaaatcgcgc
cgcaaattcctctatgacaccaacgttggcgcaggcctgccggtaattgaaaacctgcaa
aacctgcttaatgccggcgatgagctgcaacgcttctcgggcattctctccggttctctc
tcctttattttcggtaagctcgacgaagggatgagtctgtcggaagcgacaaaagtcgcg
cgcgagatgggctacaccgagccggacccgcgtgacgatctctccggtatggacgtcgca
cgcaaattattgattctggcccgtgaaaccgggcgcgagctggaactgacggatatcgtg
atcgagccggtactgccagcaagcttcgatgattccggcgaggtcgacagctttatggcg
cgtctgccgtcgctggatgatgagtttgccagccgcgtggcgaaggcccgtgacgccggc
aatgtgctgcgttatgttggcaacattgaagaggatggcacctgccgggtgaagatcgcc
gaagtcgacggcaacgatccgttgtataaggtgaaaaacggcgagaacgcgctggcgttt
tacagccactattaccagccgttgccgctggtgctgcgcggttacggcgcgggtaatgat
gttacggcggcgggcgtgtttgccgacctgctgcgtacgctttcgtggaagttaggggtc
tga
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