Kosakonia sp. SMBL-WEM22: HF650_04205
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Entry
HF650_04205 CDS
T08549
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kob
Kosakonia sp. SMBL-WEM22
Pathway
kob00300
Lysine biosynthesis
kob00550
Peptidoglycan biosynthesis
kob01100
Metabolic pathways
kob01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kob00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HF650_04205 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HF650_04205 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HF650_04205 (murF)
Enzymes [BR:
kob01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HF650_04205 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
YAcAr
Motif
Other DBs
NCBI-ProteinID:
QNQ19011
UniProt:
A0A7H0M9Q0
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Position
874909..876267
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AA seq
452 aa
AA seq
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MISVTLNQLAGTLHGELLGQDVTIDAVTSDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRKLNTDLPQLVVSDTRQAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSECGNTLYTAGNLNNDIGVPMTLLRLTREHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPANGIAILNADNNDWLNWQSIIGDRKVWRFS
PNAANSDFTATNVHITSHGTEFTLQTPTGNADVILPLPGRHNIANALAATALAMAVGASL
DAVKKGLAKLKAVPGRLFPVRLGENQLLLDDTYNANVGSMTAAAHVLAEMPGYRVMVVGD
MAELGDESEACHVQVGEAAKSVGIDKVLSVGTLSQALSDASGVGEHFNDKAAATARLKAL
IAEHPIITILVKGSRSSAMEEVVRELQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcaaccagcttgccggcacgctgcacggtgaacttttgggtcag
gacgtcacaattgacgccgtgaccagcgatacccgcaaattgacgccgggctgcttgttt
gtggcgctgaaaggcgaacgtttcgacgcccacgattttgccgaccaggctaaagcgggc
ggtgcgggcgcgctgctggtgagccgcaaactgaataccgatctgccgcagctggtggtg
agtgatacccgccaggccttcggcgaactggcggcgtgggtgcgtcagcaggtgccgacg
cgcgtcgtcgcgctgaccggctcctccggcaaaacctcggtgaaagagatgaccgctgcc
attcttagcgagtgcggcaacaccctctacactgcgggcaacctcaacaatgacatcggc
gtgccgatgaccctgctgcgtctgaccagagaacatcagtacgcggtgattgagctgggc
gctaatcaccagggtgagatcgcctggaccgttagcttaacccgcccggaagcggcgctg
gttaacaacctggccgctgcgcatctggaagggttcggatcgctggctggcgtggcgaag
gcgaaaggtgaaatttacaccggcctgccggccaacggcatcgccatcctcaatgccgat
aacaatgactggctgaactggcagagcattattggcgatcgcaaagtgtggcgcttctcg
cccaacgcggcgaacagcgattttaccgccaccaatgtgcatatcacctcgcacggtacc
gagttcacgctgcaaacgccgaccggcaatgccgacgtgattttacccctgccgggacgt
cacaacattgctaacgcgctggcggcgaccgcgctggcgatggcggtaggcgcatccctc
gatgcggtgaaaaagggtctggcgaagctgaaagcggtgccgggccgtctcttcccggtg
cgcctcggcgaaaaccagctgctgctggatgatacctataacgccaacgtcgggtcgatg
accgccgctgcgcacgtgctggcagagatgcccggctaccgcgtaatggtggtgggcgat
atggcggagttgggcgacgaaagcgaagcctgccatgttcaggtcggcgaagcggcaaaa
tccgtcggtatcgacaaggtgctgagcgtcggcacattaagtcaagcgctcagcgacgcc
agcggcgtcggcgagcatttcaacgataaagctgcggctacggcgcgtttaaaagcgctg
attgccgagcacccaatcattaccattttagtgaaaggttcacgtagctccgccatggaa
gaggtggtacgcgaattacaggagaacgggacatgttag
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